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Estimating the Relative Stiffness between a Hepatic Lesion and the Liver Parenchyma through Biomechanical Simulations of the Breathing Process

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Estimating the Relative Stiffness between a Hepatic Lesion and the Liver Parenchyma through Biomechanical Simulations of the Breathing Process

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dc.contributor.author Martinez-Sanchis, Sandra es_ES
dc.contributor.author Rupérez Moreno, María José es_ES
dc.contributor.author Nadal, Enrique es_ES
dc.contributor.author Pareja, E. es_ES
dc.contributor.author Brugger, Sara es_ES
dc.contributor.author Borzacchiello, D. es_ES
dc.contributor.author López, R. es_ES
dc.contributor.author Monserrat, C. es_ES
dc.date.accessioned 2020-06-09T03:32:10Z
dc.date.available 2020-06-09T03:32:10Z
dc.date.issued 2018-10-25 es_ES
dc.identifier.issn 1024-123X es_ES
dc.identifier.uri http://hdl.handle.net/10251/145747
dc.description.abstract [EN] In this paper, a method to in vivo estimate the relative stifness between a hepatic lesion and the liver parenchyma is presented. Tis method is based on the fnite element simulation of the deformation that the liver undergoes during the breathing process. Boundary conditions are obtained through a registration algorithm known as Coherent Point Drif (CPD), which compares the liver form in two phases of the breathing process. Finally, the relative stifness of the tumour with respect to the liver parenchyma is calculated by means of a Genetic Algorithm, which does a blind search of this parameter. Te relative stifness together with the clinical information of the patient can be used to establish the type of hepatic lesion. Te developed methodology was frst applied to a test case, i.e., to a control case where the parameters were known, in order to verify its validity. Afer that, the method was applied to two real cases and low errors were obtained. es_ES
dc.description.sponsorship This work has been funded by the Spanish Ministry of Economy and Competitiveness (MINECO) through research projects DPI2013-40859-R and TIN2014-52033-R, both also supported by European FEDER funds. es_ES
dc.language Inglés es_ES
dc.publisher Hindawi Limited es_ES
dc.relation.ispartof Mathematical Problems in Engineering es_ES
dc.rights Reconocimiento (by) es_ES
dc.subject.classification INGENIERIA MECANICA es_ES
dc.subject.classification LENGUAJES Y SISTEMAS INFORMATICOS es_ES
dc.title Estimating the Relative Stiffness between a Hepatic Lesion and the Liver Parenchyma through Biomechanical Simulations of the Breathing Process es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1155/2018/5317324 es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MINECO//TIN2014-52033-R/ES/SIMULACION DEL COMPORTAMIENTO BIOMECANICO DEL TEJIDO BLANDO EN TIEMPO REAL MEDIANTE INTELIGENCIA COMPUTACIONAL/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MINECO//DPI2013-40859-R/ES/SISTEMA DE SEGUIMIENTO DE LESIONES TUMORALES HEPATICAS MEDIANTE APROXIMACIONES BIOMECANICAS PARA DIAGNOSIS TEMPRANA Y PLANIFICACION DE TRATAMIENTO./ es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Sistemas Informáticos y Computación - Departament de Sistemes Informàtics i Computació es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Ingeniería Mecánica y de Materiales - Departament d'Enginyeria Mecànica i de Materials es_ES
dc.description.bibliographicCitation Martinez-Sanchis, S.; Rupérez Moreno, MJ.; Nadal, E.; Pareja, E.; Brugger, S.; Borzacchiello, D.; López, R.... (2018). Estimating the Relative Stiffness between a Hepatic Lesion and the Liver Parenchyma through Biomechanical Simulations of the Breathing Process. Mathematical Problems in Engineering. 1-10. https://doi.org/10.1155/2018/5317324 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.1155/2018/5317324 es_ES
dc.description.upvformatpinicio 1 es_ES
dc.description.upvformatpfin 10 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.relation.pasarela S\371189 es_ES
dc.contributor.funder Ministerio de Economía y Competitividad es_ES
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