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Genome wide association study of growth and feed efficiency traits in rabbits

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Genome wide association study of growth and feed efficiency traits in rabbits

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dc.contributor.author Garreau, Hervé es_ES
dc.contributor.author Labrune, Yann es_ES
dc.contributor.author Chapuis, Hervé es_ES
dc.contributor.author Ruesche, Julien es_ES
dc.contributor.author Riquet, Juliette es_ES
dc.contributor.author Demars, Julie es_ES
dc.contributor.author Benitez, Florence es_ES
dc.contributor.author Richard, François es_ES
dc.contributor.author Drouilhet, Laurence es_ES
dc.contributor.author Zemb, Olivier es_ES
dc.contributor.author Gilbert, Hélène es_ES
dc.date.accessioned 2023-11-03T09:23:33Z
dc.date.available 2023-11-03T09:23:33Z
dc.date.issued 2023-09-28
dc.identifier.issn 1257-5011
dc.identifier.uri http://hdl.handle.net/10251/199168
dc.description.abstract [EN] Feed efficiency is a major production trait in animal genetic breeding schemes. To further investigate the genetic control of feed efficiency in rabbits, we performed a genome-wide association study (GWAS) for growth and feed efficiency on 679 rabbits genotyped with the Affimetrix Axiom Rabbit 200K Genotyping Array. After quality control, 127 847 single-nucleotide polymorphisms (SNP) were retained for association analyses. The GWAS were performed using GEMMA software, applying a mixed univariate animal model with a linear regression on each SNP allele. The traits analysed were weight at weaning and at 63 days of age, average daily gain, total individual feed intake, feed conversion ratio and residual feed intake. No significant SNP was found for growth traits or feed intake. Fifteen genome-wide significant SNPs were detected for feed conversion ratio on OCU7, spanning from 124.8 Mbp to 126.3 Mbp, plus two isolated SNP on OCU2 (77.3 Mbp) and OCU8 (16.5 Mbp). For residual feed intake, a region on OCU18 (46.1-53.0 Mbp) was detected, which contained a putative functional candidate gene, GOT1. es_ES
dc.description.sponsorship This study is part of the Feed-a-Gene Project, funded from the European Union’s H2020 Programme under grant agreement nº 633 531. es_ES
dc.language Inglés es_ES
dc.publisher Universitat Politècnica de València es_ES
dc.relation.ispartof World Rabbit Science es_ES
dc.rights Reconocimiento - No comercial - Compartir igual (by-nc-sa) es_ES
dc.subject Feed efficiency es_ES
dc.subject SNP es_ES
dc.subject GWAS es_ES
dc.subject Genetics es_ES
dc.subject Candidate genes es_ES
dc.subject Rabbits es_ES
dc.title Genome wide association study of growth and feed efficiency traits in rabbits es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.4995/wrs.2023.18215
dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/633531 es_ES
dc.rights.accessRights Abierto es_ES
dc.description.bibliographicCitation Garreau, H.; Labrune, Y.; Chapuis, H.; Ruesche, J.; Riquet, J.; Demars, J.; Benitez, F.... (2023). Genome wide association study of growth and feed efficiency traits in rabbits. World Rabbit Science. 31(3):163-169. https://doi.org/10.4995/wrs.2023.18215 es_ES
dc.description.accrualMethod OJS es_ES
dc.relation.publisherversion https://doi.org/10.4995/wrs.2023.18215 es_ES
dc.description.upvformatpinicio 163 es_ES
dc.description.upvformatpfin 169 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 31 es_ES
dc.description.issue 3 es_ES
dc.identifier.eissn 1989-8886
dc.relation.pasarela OJS\18215 es_ES
dc.contributor.funder European Commission es_ES
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