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dc.contributor.author | Beltrán Martínez, Mª Carmen | es_ES |
dc.contributor.author | Althaus, Rafael Lisandro | es_ES |
dc.contributor.author | MOLINA CASANOVA, ANA MARIA | es_ES |
dc.contributor.author | Berruga Fernandez, Maria Isabel | es_ES |
dc.contributor.author | Molina Pons, Mª Pilar | es_ES |
dc.date.accessioned | 2016-06-03T07:59:40Z | |
dc.date.available | 2016-06-03T07:59:40Z | |
dc.date.issued | 2015-03 | |
dc.identifier.issn | 2171-9292 | |
dc.identifier.uri | http://hdl.handle.net/10251/65163 | |
dc.description | © INIA. Manuscripts published are the property of the Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria SJAR is an Open Access Journal. All articles are distributed under the terms of the Creative Commons Attribution License (CC by-nc/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | es_ES |
dc.description.abstract | [EN] The use of antibiotics to treat mastitis and other infectious diseases in dairy sheep and goats is a widespread practice nowadays that can, when not properly applied, result in the contamination of the milk supply. Spanish legislation establishes the control of the presence of antibiotic residues in sheep and goat s milk using screening methods that detect, at least, beta-lactam drugs. Microbial inhibitor tests using Geobacillus stearothermophilus var. calidolactis and specific receptor-binding assays are most widely employed for this purpose. The detection rates of screening tests routinely used in Spain have been calculated considering the frequency of use of veterinary drugs commonly applied in ovine and caprine livestock to treat and prevent mastitis as well as the test sensitivity toward these substances at safety levels. In general, the use of a single test allows detecting 62.8-82.4% of the antibiotics employed. For sheep milk, the total detection range achieved with microbial tests was significantly higher than that reached with rapid receptor tests. However, no significant differences between the two types of methods were found when goat s milk was analysed. In both types of milk, the simultaneous use of two screening tests with a different analytical basis increases the total detection range significantly,reaching values ≥ 90% in some cases (81.5-90.1% for sheep and 84.7-92.6% for goats). However, the periodical use of screening tests able to detect quinolones, macrolides or aminoglycosides would be recommended to carry out more efficient screening and ensure the safety of milk and dairy products from sheep and goats. | es_ES |
dc.description.sponsorship | This work forms part of the Project AGL2009-11524 financed by the Ministerio de Ciencia e Innovacion (Madrid, Spain). | en_EN |
dc.language | Inglés | es_ES |
dc.publisher | Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA) | es_ES |
dc.relation.ispartof | Spanish Journal of Agricultural Research | es_ES |
dc.rights | Reconocimiento - No comercial (by-nc) | es_ES |
dc.subject | Antimicrobial agents | es_ES |
dc.subject | Screening methods | es_ES |
dc.subject.classification | PRODUCCION ANIMAL | es_ES |
dc.title | Analytical strategy for the detection of antibiotic residues in sheep and goat's milk | es_ES |
dc.type | Artículo | es_ES |
dc.identifier.doi | 10.5424/sjar/2015131-6522 | |
dc.relation.projectID | info:eu-repo/grantAgreement/MICINN//AGL2009-11524/ES/Estrategia Analitica Para La Deteccion De Residuos De Antibioticos En La Leche De Oveja Y Cabra/ | es_ES |
dc.rights.accessRights | Abierto | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Departamento de Ciencia Animal - Departament de Ciència Animal | es_ES |
dc.description.bibliographicCitation | Beltrán Martínez, MC.; Althaus, RL.; Molina Casanova, AM.; Berruga Fernandez, MI.; Molina Pons, MP. (2015). Analytical strategy for the detection of antibiotic residues in sheep and goat's milk. Spanish Journal of Agricultural Research. 13(1):e05-001. https://doi.org/10.5424/sjar/2015131-6522 | es_ES |
dc.description.accrualMethod | S | es_ES |
dc.relation.publisherversion | https://dx.doi.org/10.5424/sjar/2015131-6522 | es_ES |
dc.description.upvformatpinicio | e05 | es_ES |
dc.description.upvformatpfin | 001 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |
dc.description.volume | 13 | es_ES |
dc.description.issue | 1 | es_ES |
dc.relation.senia | 302132 | es_ES |
dc.contributor.funder | Ministerio de Ciencia e Innovación | es_ES |
dc.description.references | Althaus, R. L., Torres, A., Montero, A., Balasch, S., & Molina, M. P. (2003). Detection Limits of Antimicrobials in Ewe Milk by Delvotest Photometric Measurements. Journal of Dairy Science, 86(2), 457-463. doi:10.3168/jds.s0022-0302(03)73624-8 | es_ES |
dc.description.references | Beltrán, M. C., Romero, T., Althaus, R. L., & Molina, M. P. (2013). Evaluation of the Charm maximum residue limit β-lactam and tetracycline test for the detection of antibiotics in ewe and goat milk. Journal of Dairy Science, 96(5), 2737-2745. doi:10.3168/jds.2012-6044 | es_ES |
dc.description.references | Beltrán, M. C., Althaus, R. L., Berruga, M. I., Molina, A., & Molina, M. P. (2014). Detection of antibiotics in sheep milk by receptor-binding assays. International Dairy Journal, 34(2), 184-189. doi:10.1016/j.idairyj.2013.09.006 | es_ES |
dc.description.references | BELTRÁN, M. C., BORRÀS, M., NAGEL, O., ALTHAUS, R. L., & MOLINA, M. P. (2014). Validation of Receptor-Binding Assays To Detect Antibiotics in Goat’s Milk. Journal of Food Protection, 77(2), 308-313. doi:10.4315/0362-028x.jfp-13-253 | es_ES |
dc.description.references | Beltrán, M. C., Berruga, M. I., Molina, A., Althaus, R. L., & Molina, M. P. (2015). Performance of current microbial tests for screening antibiotics in sheep and goat milk. International Dairy Journal, 41, 13-15. doi:10.1016/j.idairyj.2014.09.007 | es_ES |
dc.description.references | Berruga MI, Lozoya S, Rubio R, Castro N, Molina A, 2008. Estudio sobre las posibles causas de la presencia de residuos de antimicrobianos en la leche de ovino y caprino. Ministerio de Medio Ambiente, Medio Rural y Marino (MARM), Madrid, 102 pp. | es_ES |
dc.description.references | Berruga MI, Beltrán MC, Novés B, Molina A, Molina MP, 2011. Effect of penicillins on the acidification of yogurt made from ewe's milk during the storage. In: Science and technology against microbial pathogens - Research, development and evaluation (Mendez-Vilas A, ed.).World Sci Publ, Hackensack, NJ (USA), pp: 145-149. | es_ES |
dc.description.references | Gonzalo, C., Carriedo, J. A., García-Jimeno, M. C., Pérez-Bilbao, M., & de la Fuente, L. F. (2010). Factors influencing variation of bulk milk antibiotic residue occurrence, somatic cell count, and total bacterial count in dairy sheep flocks. Journal of Dairy Science, 93(4), 1587-1595. doi:10.3168/jds.2009-2838 | es_ES |
dc.description.references | IDF, 2013. IDF guide to prudent use of antimicrobial agents in dairy production. International Dairy Federation, Brussels, Belgium. | es_ES |
dc.description.references | Molina, M. P., Althaus, R. L., Molina, A., & Fernández, N. (2003). Antimicrobial agent detection in ewes’ milk by the microbial inhibitor test brilliant black reduction test—BRT AiM®. International Dairy Journal, 13(10), 821-826. doi:10.1016/s0958-6946(03)00107-9 | es_ES |
dc.description.references | Montero, A., Althaus, R. L., Molina, A., Berruga, I., & Molina, M. P. (2005). Detection of antimicrobial agents by a specific microbiological method (Eclipse100®) for ewe milk. Small Ruminant Research, 57(2-3), 229-237. doi:10.1016/j.smallrumres.2004.07.006 | es_ES |
dc.description.references | Nagel, O. G., Beltrán, M. C., Molina, M. P., & Althaus, R. L. (2012). Novel microbiological system for antibiotic detection in ovine milk. Small Ruminant Research, 102(1), 26-31. doi:10.1016/j.smallrumres.2011.11.018 | es_ES |
dc.description.references | Pengov, A., & Kirbis, A. (2009). Risks of antibiotic residues in milk following intramammary and intramuscular treatments in dairy sheep. Analytica Chimica Acta, 637(1-2), 13-17. doi:10.1016/j.aca.2008.09.021 | es_ES |
dc.description.references | Pirisi, A., Lauret, A., & Dubeuf, J. P. (2007). Basic and incentive payments for goat and sheep milk in relation to quality. Small Ruminant Research, 68(1-2), 167-178. doi:10.1016/j.smallrumres.2006.09.009 | es_ES |
dc.description.references | Sanders P, Bousquet-Melou A, Chauvin C, Toutain PL, 2011. Utilisation des antibiotiques en élevage et enjeux de santé publique. INRA Prod Anim 24: 199-204. | es_ES |
dc.description.references | Scintu, M. F., & Piredda, G. (2007). Typicity and biodiversity of goat and sheep milk products. Small Ruminant Research, 68(1-2), 221-231. doi:10.1016/j.smallrumres.2006.09.005 | es_ES |
dc.description.references | Sierra, D., Sánchez, A., Contreras, A., Luengo, C., Corrales, J. C., Morales, C. T., … Gonzalo, C. (2009). Detection limits of four antimicrobial residue screening tests for β-lactams in goat’s milk. Journal of Dairy Science, 92(8), 3585-3591. doi:10.3168/jds.2008-1981 | es_ES |
dc.description.references | Sierra, D., Contreras, A., Sánchez, A., Luengo, C., Corrales, J. C., Morales, C. T., … Gonzalo, C. (2009). Short communication: Detection limits of non-β-lactam antibiotics in goat’s milk by microbiological residues screening tests. Journal of Dairy Science, 92(9), 4200-4206. doi:10.3168/jds.2009-2101 | es_ES |