ABSTRACT The field of hybrid materials is one of the most attractive and emergent matter in nanoscience. The combination of different precursors with organic and inorganic fragments by self-assembling of their original structures, during the molecular framework formation process, allows to prepare materials that show unique properties with multiple applications as advanced materials. This PhD study has been focused on the design, preparation and characterization of functional catalysts based on bridged silsesquioxanes organosiliceus precursors (disilanes) using different synthesis methods. As a result, we have obtained different families of hybrid porous materials with catalytic applications. First, from layered precursors, Magadiite and MWW-P, which were subjected to exchange, swelling, pillarization and extraction processes, stable and reusable multifunctional catalysts to carried out cascade reactions were prepared containing active functional groups incorporated in their structure, like intercalated pillars, at the same time that their original textural properties were improve. A second family of non-ordered organic-inorganic mesoporous materials has been obtained, in absence of structural directing agents, through a fluoride catalized sol-gel route, achieving to introduce organic structural fragments, which are inside the network of the materials. In all of them, the influence of the disilane precursors nature on the final properties of the obtained hybrid solids has been studied. Lastly, ordered mesoporous organic-inorganic materials based in polyhedral silsesquioxanes POSS, which act as structural nodes, linked between them through disilane molecules with arilic groups were obtained following an acid micellar route. Finally, the obtained materials were functionalized by post-synthesis treatments, for the introduction of accessible active sites in their structure. All mesoporous hybrid materials, ordered and non-ordered, with active functions integrated in their structure, have been successfully used as selective catalysts to perform different process in fine chemistry.