This README.txt file was generated on 25-11-2021 by Juan Carlos Marín Payá ------------------- GENERAL INFORMATION ------------------- Title of Dataset: Biomimetic 3D Environment Based on Microgels as a Model for the Generation of Drug Resistance in Multiple Myeloma Principal Investigator: Juan Carlos Marín Payá; juancarlosmarinpaya@gmail.com (J.C.M.-P.) Associate or Co-investigator: Blanca Díaz-Benito; bldiaz03@ucm.es (B.D.-B.) Luis Amaro Martins; luisamaromartins@gmail.com (L.A.M.) Sandra Clara Trujillo; sanclatr@gmail.com (S.C.T.) Lourdes Cordón; lou.cordon@gmail.com (L.C.) Senentxu Lanceros-Méndez; senentxu.lanceros@bcmaterials.net (S.L.-M.) Gloria Gallego Ferrer; ggallego@ter.upv.es (G.G.F.) Amparo Sempere; sempere_amp@gva.es (A.S.) José Luis Gómez Ribelles; jlgomez@ter.upv.es (J.L.G.R.) Conceptualization, J.C.M.-P. and J.L.G.R.; investigation, resources, and formal analysis, J.C.M.-P., L.A.M., B.D.-B., A.S. and J.L.G.R.; writing—original draft preparation, J.C.M.-P., J.L.G.R. and A.S.; writing—review and editing, S.C.T., L.C., S.L.-M. and G.G.F.; funding acquisition, J.L.G.R., A.S. and S.L.-M. Date of data collection: 24-11-2020 Geographic location of data collection: Centre for Biomaterials and Tissue Engineering, CBIT, Universitat Politècnica de València, 46022 Valencia and Haematology Department, Hospital Universitari i Politècnic La Fe, 46026 Valencia, Spain Information about funding sources or sponsorship that supported the collection of the data: Funding by the Generalitat Valenciana PROMETEO/2016/063 General description: Data obtained during the project to demonstrate CAM-DR effect of hyaluronic acid or collagen by the development of 3D culture based on microgel Keywords: biopolymers; biocomposites; multiple myeloma; microgel; hyaluronic acid; collagen. -------------------------- SHARING/ACCESS INFORMATION -------------------------- Open Access to data: Open Citation for and links to publications that cite or use the data: https://doi.org/10.3390/ma14237121 -------------------- DATA & FILE OVERVIEW -------------------- File list: GraphPad CAM-DR assay Dexamethasone: Results of data obtained by flow cytometry on cell mortality Cell cycle 2-5-7 Days: Results of data obtained by flow cytometry on cell cycle Cell viability 2-5-7 days: Results of data obtained by flow cytometry on cell viability Dexamethasone assay: Results of data obtained by flow cytometry on cell mortality using different concentration of dexamethasone FTIR 900-1500: Results of data by FTIR of different peaks at 900 to 1500 FTIR 2840-2941: Results of data by FTIR of different peaks at 2840 to 2941 Histogram of alginate microspheres: Results of data of the size of alginate microspheres PicoGreen 2-5-7 Days: Results of data obtained by Picogreen assay of the cell number of cells in each condition Type of version of the dataset: Data and processed data Total size: 269 KB -------------------------- METHODOLOGICAL INFORMATION -------------------------- Description of methods used for collection/generation of data: https://doi.org/10.3390/ma14237121 Methods for processing the data: The ANOVA one-way analysis (Bonferroni test) was used to determine statistically significant differences between groups by the IBM SPSS Statistics software version 20.0 considering p ? 0.05 significant, and data were presented as mean ± SD Software- or Instrument-specific information needed to interpret the data, including software and hardware version numbers: Flow cytometry: Kaluza 2.1 software PicoGreen and Micro-BCA: Victor3 Plate Reader Microsphere’s visualization: FESEM, ULTRA 55 model, ZEISS