ABSTRACT The goal of this Thesis is to propose a theoretical formalization of the high cycle fatigue process in ductile metals. That is a very complex interdisciplinary field, with many branches in various technological fields and with a very large and historically extensive experimentation, especially focused on metals and simple stress states. It is therefore considered that this thesis would include primarily the references and theoretical elements necessary for a suited subsequent exposure of the phenomenology, the associated modeling and the essential contributions of the research in this field. This objective is developed in the first chapter. The first two sections of Chapter 2 are intended for the description of the current state of empirical modeling of high cycle fatigue in uniaxial processes and their damage accumulation. The third section of this chapter is a description of the current state of research on fatigue in general, and, specially, on the generation and evolution of damage, with particular reference on his thermodynamic background. The fourth section of this chapter presents a theoretical proposition appropriate to formalize such previous results and to develop research that is intended. Therefore, this proposed theoretical modeling is considered as a contribution, but not an essential contribution of this thesis, since it is an established ad hoc proposal to meet its research objectives. Chapter 3 provides the first substantial contribution of this thesis. This chapter proposes a new theoretical modeling of damage that does not include an internal variable independent of damage. Indeed, it exposes the weakness of the models founded on the assumption of that hypothesis. Therefore, in this Thesis it is considered that the associated variable of the damage evolution cannot be other than the real tension in every moment and it is exposed a new damage formalization based on this concept. It has been found that the proposed model is a generalization of the classical damage model when it is applied to uniaxial processes and that it further solves the intrinsic difficulty that the classical damage model presents in anisotropic stress states resulted from any external action, checking its suitability with previous results obtained from the models with internal independent variables of damage. Chapter 4 is intended to present a second essential contribution of this work, the proposal of new energy multiaxial hybrid criterion for initiation of fatigue, or damage. Then, it is defined a new boundary surface damage growth and its temporal evolution under equations formally equivalent to the plastic deformation evolution equations. This general approach has a great alignment with previous diverse experimental results multiaxial hybrid. The new model proposed in Chapters 3 and 4 shows an absolute formal parallelism with the theoretical model of plastic deformation process, thus allowing the development of simpler models of coupling damage with elastic or plastic deformations. Chapter 5 introduces the concept of stress concentration, inherent in the evolution of damage by crack advance, and a theoretical description of accumulation of damage in high cycle fatigue is proposed and the phenomenology described by Wöhler curves is reproduced. Moreover, the stress concentration approach proposed here can be extended to aspects relating to rigidity and an application is developed in the case of a straight structural bar element. A final contribution is proposed in this thesis, with the proposal of a structural estimation model that includes joint stiffness due to high cycle fatigue. Chapter 6 presents the analysis of the partial conclusions established in the development of this work and the formulation of possible further research.