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Browsing by Author "Kiefer, Falk"

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Browsing by Author "Kiefer, Falk"

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    Chronic alcohol consumption alters extracellular space geometry and transmitter diffusion in the brain 
    De Santis, Silvia; Cosa-Liñán, Alejandro; Garcia-Hernandez, Raquel; Dmytrenko, Lesia; Vargova, Lydia; Vorisek, Ivan; Stopponi, Serena; Bach, Patrick; Kirsch, Peter; Kiefer, Falk; Ciccocioppo, Roberto; Sykova, Eva; Moratal, David; Sommer, Wolfgang H.; Canals, Santiago (American Association for the Advancement of Science, 2020-06)
    [EN] Already moderate alcohol consumption has detrimental long-term effects on brain function. However, how alcohol produces its potent addictive effects despite being a weak reinforcer is a poorly understood conundrum ...
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    Increased network centrality of the anterior insula in early abstinence from alcohol 
    Bordier, C; Weil, Georg; Bach, Patrick; Scuppa, G; Nicolini , C; Forcellini, G; Pérez-Ramírez, María Úrsula; Moratal, David; Canals-Gamoneda, Santiago; Hoffmann, Sabine; Hermann, Derik; Vollstädt-Klein, Sabine; Kiefer, Falk; Kirsch, Peter; Sommer, W (Blackwell Publishing, 2022-01)
    [EN] Abnormal resting-state functional connectivity, as measured by functional magnetic resonance imaging (MRI), has been reported in alcohol use disorders (AUD), but findings are so far inconsistent. Here, we exploited ...
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    Incubation of neural alcohol cue reactivity after withdrawal and its blockade by naltrexone 
    Bach, Patrick; Weil, Georg; Pompili, Enrico; Hoffmann, Sabine; Hermann, Derik; Vollstädt-Klein, Sabine; Mann, Karl; Pérez-Ramírez, Úrsula; Moratal, David; Canals, Santiago; Dursun, Serdar M.; Greenshaw, Andrew J.; Kirsch, Peter; Kiefer, Falk; Sommer, Wolfgang H. (Blackwell Publishing, 2020-01)
    [EN] During the first weeks of abstinence, alcohol craving in patients may increase or "incubate." We hypothesize that Naltrexone (NTX) blocks this incubation effect. Here, we compared NTX effects on neural alcohol cue ...