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Browsing by Author "Bosca Mayans, Francisco"

Now showing items 1-20 of 41

A continuous-flow catalytic process with natural hematite-alginate beads for effective water decontamination and disinfection: Peroxymonosulfate activation leading to dominant sulfate radical and minor non-radical pathways

Mohammadi, Samira; Moussavi, Gholamreza; Shekoohiyan, Sakine; Marín García, Mª Luisa; Bosca Mayans, Francisco; Giannakis, Stefanos (Elsevier, 2021-05-01)

[EN] A natural, ferruginous material, Hormuz Red Soil (HRS), was used as a catalyst for decontamination and disinfection via PMS activation. The HRS was fully characterized (morphological, structural, chemical properties) ...
A highly efficient supported TiO2 photocatalyst for wastewater remediation in continuous flow

Cabezuelo, Oscar; Ponce-Gonzalez, Luis Nicolas; Marín García, Mª Luisa; Bosca Mayans, Francisco (Elsevier BV, 2023-12)

[EN] Although TiO2 materials have been extensively studied as photocatalysts, there is not any commercial TiO2- supported photocatalyst used for wastewater remediation. This fact set the goal to synthesize a new supported ...
Analysis of mebendazole binding to its target biomolecule by laser flash photolysis

Jornet Olivé, Mª Dolors; Bosca Mayans, Francisco; Andreu, Jose Maria; Domingo, L.R.; Tormos Faus, Rosa Esperanza; Miranda Alonso, Miguel Ángel (Elsevier, 2016-02)

[EN] Mebendazole (MBZ) and related anticancer benzimidazoles act binding the beta-subunit of Tubulin (TU) before dimerization with alpha-TU with subsequent blocking microtubule formation. Laser flash photolysis (LFP) is a ...
Antineoplastic tropolone derivatives as useful biomarkers: fluorescence enhancement upon binding to biological targets

Tormos Faus, Rosa Esperanza; Bosca Mayans, Francisco (Royal Society of Chemistry, 2013)

It has been observed for the first time that the binding of tropolone derivatives to human serum albumin (HSA) produce a high fluorescence promotion. Important evidence of the immobilization of these drugs into the protein ...
Assessing physical properties of amphoteric fluoroquinolones using phosphorescence spectroscopy

Soldevila Serrano, Sonia; Bosca Mayans, Francisco (Elsevier, 2020-02-15)

[EN] The self-association of fluoroquinolones (FQ) in water would play a relevant role in their translocations across lipid membranes. Triplet excited states of these drugs have been shown as reporters of FQ self-association ...
Behavior of Drug Excited States within Macromolecules: Binding of Colchicine and Derivatives to Albumin

Bosca Mayans, Francisco; Tormos Faus, Rosa Esperanza (American Chemical Society, 2013-06-27)

The aqueous solutions of colchicine (COL) and analogues such as colchiceine (CEI), and N-deacetylcolchiceine (DCEI) have been studied by laser flash photolysis (LFP) with and without the presence of human serum albumin ...
Biradical vs singlet oxygen photogeneration in suprofen cholesterol systems

Palumbo, Fabrizio; Bosca Mayans, Francisco; Morera Bertomeu, Isabel María; Andreu Ros, María Inmaculada; Miranda Alonso, Miguel Ángel (Beilstein-Institut, 2016-06-14)

Cholesterol (Ch) is an important lipidic building block and a target for oxidative degradation, which can be induced via free radicals or singlet oxygen (1O2). Suprofen (SP) is a nonsteroidal anti-inflammatory drug that ...
Chemical tuning for potential antitumor fluoroquinolones

Anaya-González, Cristina; Soldevila Serrano, Sonia; García-Laínez, Guillermo; Bosca Mayans, Francisco; Andreu Ros, María Inmaculada (Elsevier, 2019-09)

[EN] Phototoxic effects of 6,8 dihalogenated quinolones confers to this type of molecules a potential property as photochemotherapeutic agents. Two photodehalogenation processes seem to be involved in the remarkable ...
Desarrollo de nuevos fotocatalizadores de dióxido de titanio para la fotodegradación de contaminantes en aguas utilizadas para el tratamiento post-cosecha de frutas

Valero Muñoz, María del Carmen (Universitat Politècnica de València, 2018-01-09)

[ES] En este proyecto se han sintetizado tres nuevos fotocatalizadores todos ellos formados por dióxido de titanio sobre microesferas de sílice, y a dos de estos fotocatalizadores se les han depositado nanopartículas de ...
Desarrollo de nuevos fotocatalizadores heterogéneos basados en colorantes orgánicos para la fotodegradación de contaminantes fenólicos

Bañón Juares, Héctor (Universitat Politècnica de València, 2019-01-23)

El objetivo de este proyecto es sintetizar nuevos fotocatalizadores heterogéneos basados en colorantes orgánicos, y estudiar su potencial en la fotodegradación de contaminantes fenólicos como el propio fenol, el 2-fenilfenol, ...
Desarrollo de nuevos fotocatalizadores heterogéneos basados en WO3 para la descontaminación de aguas residuales

Diego López, Ander (Universitat Politècnica de València, 2021-09-24)

[ES] Los procesos de oxidación avanzada, caracterizados por su capacidad de generar especies con gran poder oxidante, son una de las soluciones para la eliminación de compuestos orgánicos no biodegradables en aguas ...
Design of New Up-conversion Systems for Anticancer Therapies

Anaya González, Cristina (Universitat Politècnica de València, 2021-07-19)

[ES] El cáncer es una de las principales causas de muerte a nivel mundial. Los tratamientos anticancerígenos generalmente usados tienen diversos efectos secundarios producidos por su baja especificidad. Esta es una de las ...
Diseño y síntesis de nuevos fotocatalizadores para el tratamiento de aguas residuales

Cabezuelo Gandía, Oscar (Universitat Politècnica de València, 2024-09-02)

[ES] Las tecnologías convencionales para el tratamiento de aguas contaminadas no logran abordar la eliminación de contaminantes de preocupación emergente (CECs), lo que subraya la necesidad de implementar nuevas estrategias ...
Drug-DNA complexation as the key factor in photosensitized thymine dimerization

Cuquerella Alabort, Maria Consuelo; Lhiaubet, Virginie Lyria; Miranda Alonso, Miguel Ángel; Bosca Mayans, Francisco (The Royal Society of Chemistry, 2017)

[EN] The crucial role of photosensitizer@DNA complexation in the formation of cyclobutane pyrimidine dimers (CPDs) has been demonstrated using femtosecond and nanosecond transient absorption and emission measurements in ...
Drug-tubulin interactions interrogated by transient absorption spectroscopy

Bosca Mayans, Francisco; Sastre Navarro, German Ignacio; Andreu, José María; Jornet, David; Tormos Faus, Rosa Esperanza; Miranda Alonso, Miguel Ángel (Royal Society of Chemistry, 2015)

[EN] Colchicine (COL) is a bioactive molecule with antitumor properties. When COL binds to tubulin (TU), it inhibits microtubule assembly dynamics. We have investigated COL-TU interactions using laser flash photolysis (LFP) ...
Electronic and Functional Scope of Boronic Acid Derived Salicylidenehydrazone (BASHY) Complexes as Fluorescent Dyes

Alcaide, M.M.; Santos, F.M.F.; Pais, V.F.; Carvalho, J.I.; Collado, Daniel; Pérez-Inestrosa, E.; Arteaga, Jesus F.; Bosca Mayans, Francisco; Gois, P.M P.; Pischel, Uwe (American Chemical Society, 2017-07-21)

[EN] A series of boronic acid derived salicylidenehydrazone (BASHY) complexes was prepared and photophysically characterized. The dye platform can be modified by (a) electronic tuning along the cyanine-type axis via ...
ESTUDIO DE LA FOTOREACTIVIDAD DE LAS FLUOROQUINOLONAS CON SUS BIOMOLÉCULAS DIANA

Soldevila Serrano, Sonia (Universitat Politècnica de València, 2016-01-07)

[EN] Fluoroquinolones (FQ) are the antibiotics most used nowadays. Some of its derivatives have anti-tumor activity. Both in vitro and in vivo studies have shown anti-cancer property of these compounds. Its mechanism of ...
Heterogeneous riboflavin-based photocatalyst for pollutant oxidation through electron transfer processes

Cabezuelo-Gandia, Oscar; Martínez-Haya, Rebeca; Montes, Noelia; Bosca Mayans, Francisco; Marín García, Mª Luisa (Elsevier, 2021-12-05)

[EN] Organic photocatalysts could employ visible light to produce photodegradation of pollutants; however, their low photostability prevents their reuse even when they are supported on solid materials. Herein, to obtain a ...
Optimizing the use of light in supported TiO2 photocatalysts: Relevance of the shell thickness

Cabezuelo-Gandia, Oscar; Diego-López, Ander; Atienzar Corvillo, Pedro Enrique; Marín García, Mª Luisa; Bosca Mayans, Francisco (Elsevier, 2023-10-01)

[EN] Heterogeneous photocatalysts have attracted significant interest over the last few years. In this sense, improved photocatalytic properties for SiO2@TiO2 materials have been correlated with higher semiconductor's ...
Photoreactivity of fluoroquinolones: nature of aryl cations generated in water

Soldevila Serrano, Sonia; Bosca Mayans, Francisco (American Chemical Society, 2012)

The nature of stabilized aryl cations generated from photodehalogenations of fluoroquinolones in aqueous media has been studied by comparing the photophysical and photochemical behavior of lomefloxacin (LFX) and its ...