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Browsing by Author "Gago Zachert, Selma Persida"

Now showing items 1-7 of 7

Different rates of spontaneous mutation of chloroplastic and nuclear viroids as determined by high-fidelity ultra-deep sequencing

López-Carrasco, María Amparo; Ballesteros Martínez, Cristina; Sentandreu, V.; Delgado Villar, Sonia Guadalupe; Gago Zachert, Selma Persida; FLORES PEDAUYE, RICARDO; Sanjuan Verdeguer, Rafael (Public Library of Science, 2017-09-14)

[EN] Mutation rates vary by orders of magnitude across biological systems, being higher for simpler genomes. The simplest known genomes correspond to viroids, subviral plant replicons constituted by circular non-coding ...
ICTV Virus Taxonomy Profile: Ophioviridae

Garcia, M.L; Dal Bo, Elena; da Graca, John V.; Gago Zachert, Selma Persida; Hammond, J; Moreno, Pedro; Natsuaki, T; Pallás Benet, Vicente; Navarro Bohigues, José Antonio; Reyes, Carina; Luna, Gabriel Robles; Sasaya, Takahide; Tzanetakis, Loannis E.; Vaira, Anna Maria; Verbeek, Martin (Microbiology Society, 2017)

[EN] The Ophioviridae is a family of filamentous plant viruses, with single-stranded negative, and possibly ambisense, RNA genomes of 11.3-12.5 kb divided into 3-4 segments, each encapsidated separately. Virions are naked ...
Resistencia a viroides inducida por ribozimas de cabeza de martillo y RNAs interferentes

Carbonell Olivares, Alberto (Universitat Politècnica de València, 2008-05-07)

Los viroides, los agentes infecciosos conocidos más simples, están constituidos por una molécula circular de RNA monocatenario. A pesar de su pequeño tamaño (246-401 nt) y de no codificar proteínas, son capaces de replicarse ...
Rolling-circle replication of viroids, viroid-like satellite RNAs and hepatitis delta virus: variations on a theme

Flores Pedauye, Ricardo; Grubb, Clayton Douglas; Elleuch, Amine; Nohales Zafra, Maria Angeles; Delgado, Sonia; Gago Zachert, Selma Persida (Taylor & Francis, 2011-04)

[EN] Viroids and viroid-like satellite RNAs from plants, and the human hepatitis delta virus (HDV) RNA share some properties that include small size, circularity and replication through a rolling-circle mechanism. Replication ...
The transcription initiation sites of eggplant latent viroid strands map within distinct motifs in their in vivo RNA conformations

López-Carrasco, María Amparo; Gago Zachert, Selma Persida; Mileti, Giuseppe; Minoia, Sofia; Flores Pedauye, Ricardo; Delgado Villar, Sonia Guadalupe (Taylor & Francis, 2016-01-02)

[EN] Eggplant latent viroid (ELVd), like other members of family Avsunviroidae, replicates in plastids through a symmetric rolling-circle mechanism in which elongation of RNA strands is most likely catalyzed by a nuclear-encoded ...
Trans-cleaving hammerhead ribozymes with tertiary stabilizing motifs: in vitro and in vivo activity against a structured viroid RNA

Carbonell, Alberto; Flores Pedauye, Ricardo; Gago Zachert, Selma Persida (Oxford University Press (OUP): Policy C - Option B, 2011)

[EN] Trans-cleaving hammerheads with discontinuous or extended stem I and with tertiary stabilizing motifs (TSMs) have been tested previously against short RNA substrates in vitro at low Mg2+ concentration. However, the ...
Viroids: survivors from the RNA world?

FLORES PEDAUYE, RICARDO; Gago Zachert, Selma Persida; SERRA ALFONSO, PEDRO; Sanjuan Verdeguer, Rafael; ELENA FITO, SANTIAGO FCO (Annual Reviews, 2014)

[EN] Because RNA can be a carrier of genetic information and a biocatalyst, there is a consensus that it emerged before DNA and proteins, which eventually assumed these roles and relegated RNA to intermediate functions. ...