[EN] Mutation rates vary by orders of magnitude across biological systems, being higher for simpler genomes. The simplest known genomes correspond to viroids, subviral plant replicons constituted by circular non-coding ...
Garcia, M.L; Dal Bo, Elena; da Graca, John V.; Gago Zachert, Selma Persida; Hammond, J; Moreno, Pedro; Natsuaki, T; Pallás Benet, Vicente; Navarro Bohigues, José Antonio; Reyes, Carina; Luna, Gabriel Robles; Sasaya, Takahide; Tzanetakis, Loannis E.; Vaira, Anna Maria; Verbeek, Martin(Microbiology Society, 2017)
[EN] The Ophioviridae is a family of filamentous plant viruses, with single-stranded negative, and possibly ambisense, RNA genomes of 11.3-12.5 kb divided into 3-4 segments, each encapsidated separately. Virions are naked ...
Carbonell Olivares, Alberto(Universitat Politècnica de València, 2008-05-07)
Los viroides, los agentes infecciosos conocidos más simples, están constituidos por una molécula circular de RNA monocatenario. A pesar de su pequeño tamaño (246-401 nt) y de no codificar proteínas, son capaces de replicarse ...
[EN] Viroids and viroid-like satellite RNAs from plants, and the human hepatitis delta virus (HDV) RNA share some properties that include small size, circularity and replication through a rolling-circle mechanism. Replication ...
[EN] Eggplant latent viroid (ELVd), like other members of family Avsunviroidae, replicates in plastids through a symmetric rolling-circle mechanism in which elongation of RNA strands is most likely catalyzed by a nuclear-encoded ...
Carbonell, Alberto; Flores Pedauye, Ricardo; Gago Zachert, Selma Persida(Oxford University Press (OUP): Policy C - Option B, 2011)
[EN] Trans-cleaving hammerheads with discontinuous or extended stem I and with tertiary stabilizing motifs (TSMs) have been tested previously against short RNA substrates in vitro at low Mg2+ concentration. However, the ...
FLORES PEDAUYE, RICARDO; Gago Zachert, Selma Persida; SERRA ALFONSO, PEDRO; Sanjuan Verdeguer, Rafael; ELENA FITO, SANTIAGO FCO(Annual Reviews, 2014)
[EN] Because RNA can be a carrier of genetic information and a biocatalyst, there
is a consensus that it emerged before DNA and proteins, which eventually
assumed these roles and relegated RNA to intermediate functions. ...