Apel, Pavel Yu; Ramirez Hoyos, Patricio; Blonskaya, Irina V.; Orelovitch, Oleg L.; Sartowska, Bozena A.(Royal Society of Chemistry, 2014)
Single track-etched conical nanopores in polymer foils have attracted considerable attention in recent years due to their potential applications in biosensing, nanofluidics, information processing, and other fields. The ...
Single-track, asymmetric nanopores can currently be functionalised with a spatially inhomogeneous distribution of fixed charges and a variety of pore tip shapes. Optimising the asymmetric nanopore characteristics is crucial ...
Mubarak, Ali; Ramirez Hoyos, Patricio; Tahir, Muhammad Nawaz; Mafé, Salvador; Siwy, Zuzanna S.; Neumann, Reinhard; Tremel, W.; Ensinger, Wolfgang J.(Royal Society of Chemistry, 2011-03-18)
We demonstrate the supramolecular bioconjugation of concanavalin A (Con A) protein with glycoenzyme horseradish peroxidase (HRP) inside single nanopores, fabricated in heavy ion tracked polymer membranes. Firstly, the ...
Calcium binding to fixed charge groups confined over nanoscale regions is relevant to ion equilibrium and transport in the ionic channels of the cell membranes and artificial nanopores. We present an experimental and ...
Nanochannel-based biosensing devices have been proposed for selective detection of protein analyte molecules. However, the design and miniaturization of reusable channel-based biosensors is still a challenge in nanoscience ...
[EN] We demonstrate experimentally and theoretically a nanofluidic
device for the selective recognition of the cesium ion by exploiting
host¿guest interactions inside confined geometry. For this purpose, a host
molecule, ...
We explore the electrical rectification of large amplitude fluctuating signals by an asymmetric nanostructure
operating in aqueous solution. We show experimentally and theoretically that a load capacitor can be
charged ...
[EN] Nanopore-based logical schemes in ionic solutions typically involve single gates and chemical inputs. The design of computer-like functions requires the consecutive concatenation of several gates and the use of ...
The possibility of taking advantage of a fluctuating environment for energy and information transduction is a significant challenge in biological and artificial nanostructures. We demonstrate here directional electrical ...
Ali, Mubarak; Ramirez Hoyos, Patricio; Nasir, Saima; Nguyen, Quoc-Hung; Ensinger, Wolfgang; Mafé, Salvador(Royal Society of Chemistry, 2014-07-09)
Blocking of a charged pore by an oppositely charged nanoparticle can support rectifying properties in a cylindrical nanopore, as opposed to the usual case of a fixed asymmetry in the pore geometry and charge distribution. ...
Ramirez Hoyos, Patricio; Gómez Lozano, Vicente; Verdia-Baguena, C.; Nasir, Saima; Ali, M.; Ensinger, W.; Mafe, S.(The Royal Society of Chemistry, 2016)
[EN] Membranes with nanofluidic diodes allow the selective control of molecules in physiological salt solutions at ambient temperature. The electrical coupling of the membranes with conventional electronic elements such ...
Apel, Pavel Yu; Blonskaya, Irina V.; Orelovitch, Oleg L.; Ramirez Hoyos, Patricio; Sartowska, Bozena A.(IOP Publishing: Hybrid Open Access, 2011-03-16)
We present the results of systematic studies of ion current rectification performed on artificial asymmetric nanopores with different geometries and dimensions. The nanopores are fabricated by the ion track etching method ...
Queralt-Martín, María; García Giménez, Elena; Aguilella, Vicente-Manuel; Ramirez Hoyos, Patricio; Mafé, Salvador; Alcaraz González, Antonio(American Institute of Physics (AIP), 2013-07)
We show experimentally and theoretically that significant currents can be obtained with a biological ion channel, the OmpF porin of Escherichia coli, using zero-average potentials as driving forces. The channel rectifying ...
Electrical transduction from fluctuating external signals is central to energy conversion based
on nanoscale electrochemical devices and bioelectronics interfaces. We demonstrate theoretically
and experimentally a ...
Verdia-Baguena, Carmina; Gómez Lozano, Vicente; Cervera, J.; Ramirez Hoyos, Patricio; Mafe, S.(The Royal Society of Chemistry, 2017)
[EN] We demonstrate the electrical rectification and signal averaging of fluctuating signals using a biological nanostructure in aqueous solution: a single protein ion channel inserted in the lipid bilayer characteristic ...
We have designed and characterized a cylindrical nanopore that exhibits high electrochemical
current rectification ratios at low and intermediate electrolyte concentrations. For this
purpose, the track-etched single ...
[EN] The chemical and physical input signals characteristic of micro- and nanofluidic devices operating in
ionic solutions should eventually be translated into output electric currents and potentials that are
monitored ...
Ramirez Hoyos, Patricio; Ali, Mubarak; Ensinger, Wolfgang; Mafe, Salvador(American Institute of Physics, 2012)
[EN] We show that a multifunctional nanofluidic diode, based on a single pH-sensitive polymeric pore, can be used for different information processing tasks. This fact should permit a significant simplification of the logic ...
Ali, Mubarak; Ahmed, Ishtiaq; Nasir, Saima; Ramirez Hoyos, Patricio; Niemeyer, Christof M; Mafe, Salvador; Ensinger, Wolfgang(American Chemical Society, 2015-09)
We describe the fabrication of a chemical-sensitive nanofluidic device based on asymmetric nanopores whose transport characteristics can be modulated upon exposure to hydrogen peroxide (H2O2). We show experimentally and ...
[EN] We design and characterize a nanofluidic device for the label-free specific detection of histamine neurotransmitter based on a metal ion displacement mechanism. The sensor consists of an asymmetric polymer nanopore ...