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Browsing by Author "Aznar Gimeno, Elena"

Now showing items 1-20 of 76

A fluorogenic capped mesoporous aptasensor for gluten detection

Pla, Luis; Martínez-Bisbal, M.Carmen; Aznar, Elena; Sancenón Galarza, Félix; Martínez-Máñez, Ramón; Santiago Felipe, Sara (Elsevier, 2021-02-22)

[EN] Celiac disease is a complex and autoimmune disorder caused by the ingestion of gluten affecting almost 1% of global population. Nowadays an effective treatment does not exist, and the only way to manage the disease ...
A gated material as immunosensor for in-tissue detection of IDH1-R132H mutation in gliomas

Pla, Luis; Sancenón Galarza, Félix; Martínez-Bisbal, M.Carmen; Prat-Acín, Ricardo; Galeano-Senabre, Inmaculada; Botello-Marabotto, Marina Dolores; Palanca-Suela, Sarai; Aznar, Elena; Santiago Felipe, Sara; Martínez-Máñez, Ramón (Elsevier, 2021-10-15)

[EN] A nanodevice consisted on nanoporous anodic alumina (NAA) supports functionalized with specific and selective antibody-based gatekeepers for the detection of IDH1-R132H mutant enzyme is here reported. Molecular profile ...
A Mycoplasma Genomic DNA Probe using Gated Nanoporous Anodic Alumina

Pla, Luis; Xifre Perez, Elisabet; Ribes, Àngela; Aznar, Elena; Marcos Martínez, María Dolores; Marsal, L.F.; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (John Wiley & Sons, 2017)

[EN] A nanoporous anodic alumina (NAA)-based sensor system for the detection of Mycoplasma was developed through the implementation of "molecular gates" selective to the presence of this bacterium. The capped support showed ...
Amidase-responsive controlled release of antitumoral drug into intracellular media using gluconamide-capped mesoporous silica nanoparticles

Candel Busquets, Inmaculada; Aznar Gimeno, Elena; Mondragón Martínez, Laura; De la Torre Paredes, Cristina; Martínez Mañez, Ramón; Sancenón Galarza, Félix; Marcos Martínez, María Dolores; Amoros del Toro, Pedro Jose; Guillem, Carmen; Pérez Payá, Enrique; Costero Nieto, Ana María; Gil Grau, Salvador; Parra Álvarez, Margarita (Royal Society of Chemistry, 2012-10-02)

MCM-41 silica nanoparticles were used as inorganic scaffolding to prepare a nanoscopic-capped hybrid material S1, which was able to release an entrapped cargo in the presence of certain enzymes, whereas in the absence of ...
An Interactive Model of Communication between Abiotic Nanodevices and Microorganisms

de Luis-Fernández, Beatriz; Llopis-Lorente, Antoni; Rincón, Paola; Gadea Vacas, José; Sancenón Galarza, Félix; Aznar, Elena; Villalonga, Reynaldo; Murguía, Jose R.; Martínez-Máñez, Ramón (John Wiley & Sons, 2019-10-14)

[EN] The construction of communication models at the micro¿/nanoscale involving abiotic nanodevices and living organisms has the potential to open a wide range of applications in biomedical and communication technologies. ...
Andamios de CaP funcionalizados con compuestos antimicrobianos para favorecer la reparación ósea in vivo

Melitón Barbancho, Sandra (Universitat Politècnica de València, 2020-07-02)

[ES] El creciente número de prótesis utilizadas en la medicina moderna ha mejorado la calidad de vida de muchos pacientes, sin embargo, han surgido nuevos problemas como consecuencia de su uso. Las tasas de infecciones ...
Antibacterial Activity of Linezolid against Gram-Negative Bacteria: Utilization of E-Poly-l-Lysine Capped Silica Xerogel as an Activating Carrier

Guzel Kaya, Gulcihan; Medaglia, Serena; Candela-Noguera, Vicente; Tormo-Mas, María Ángeles; Marcos Martínez, María Dolores; Aznar, Elena; Deveci, Huseyin; Martínez-Máñez, Ramón (MDPI AG, 2020-11)

[EN] In recent times, many approaches have been developed against drug resistant Gram-negative bacteria. However, low-cost high effective materials which could broaden the spectrum of antibiotics are still needed. In this ...
Antimicrobial activity of commercial calcium phosphate based materials functionalized with vanillin

Polo, Lorena; Díaz de Greñu-Puertas, Borja; Della Bella, Elena; Pagani, Stefania; Torricelli, Paola; Vivancos, José-Luis; Ruiz Rico, María; Barat Baviera, José Manuel; Aznar, Elena; Martínez-Máñez, Ramón; Fini, Milena; Sancenón Galarza, Félix (Elsevier, 2018-11)

[EN] Infections represent one of the most frequent causes of arthroplasty revision. Thus, design of new antimi-crobial scaffolds to reduce implant rejections, bone infections and associated medical costs is highlydesired. ...
Aptamer-Capped nanoporous anodic alumina for Staphylococcus aureus detection

Pla, Luis; Santiago Felipe, Sara; Tormo-Mas, María Ángeles; Pemán, Javier; Sancenón Galarza, Félix; Aznar, Elena; Martínez-Máñez, Ramón (Elsevier, 2020-10-01)

[EN] The development of new detection systems for an accurate and rapid identification of pathogens has become an essential challenge in the biomedical field. Herein a highly selective platform based on aptamer-gated nano ...
Delivery modulation in silica mesoporous supports via alkyl chain pore outlet decoration

Aznar Gimeno, Elena; Sancenón Galarza, Félix; Marcos Martínez, María Dolores; Martínez Mañez, Ramón; STROEVE, PIETER; Cano, Joan; AMOROS DEL TORO, PEDRO (American Chemical Society, 2012-12-19)

This article focuses on the study of the release rate in a family of modified silica mesoporous supports. A collection of solids containing ethyl, butyl, hexyl, octyl, decyl, octadecyl, docosyl, and triacontyl groups ...
Desarrollo de nanopartículas dirigidas para el trasporte de ADN de interés en terapia génica

Navarro Plaza, María del Carmen (Universitat Politècnica de València, 2014-06-09)

[ES] La terapia génica es una terapia avanzada que tiene como objetivo la utilización de los ácidos nucleicos como medicamentos. Su potencial terapéutico es muy amplio y abarca prácticamente todas las patologías. Sin ...
Desarrollo de scaffolds inteligentes para la prevención y tratamiento de la infección ósea

Polo Aguado, Lorena (Universitat Politècnica de València, 2016-11-02)

[EN] Bone infection is one of the most common problems that usually appear after a prosthesis surgery. In this work, we propose the development and characterisation of a mesoporous material, which can be 3D-printed in the ...
Design of enzyme-mediated controlled release systems based on silica mesoporous supports capped with ester-glycol groups

Agostini, Alessandro; Mondragón Martínez, Laura; Pascual Vidal, Lluís; Aznar Gimeno, Elena; Coll Merino, Mª Carmen; Martínez Mañez, Ramón; Sancenón Galarza, Félix; Soto Camino, Juan; Marcos Martínez, María Dolores; Amoros del Toro, Pedro; Costero, Ana M.; Parra, Margarita; Gil, Salvador (American Chemical Society, 2012-09-21)

[EN] An ethylene glycol-capped hybrid material for the controlled release of molecules in the presence of esterase enzyme has been prepared. The final organic-inorganic hybrid solid S1 was synthesized by a two-step procedure. ...
Design of enzyme-mediated controlled release systems based on silica mesoporous supports capped with ester-glycol groups

Pascual Vidal, Lluís (Universitat Politècnica de València, 2016-02-01)

An ethylene glycol capped hybrid material for the controlled release of molecules in the presence of esterase enzyme has been prepared. The final organic-inorganic hybrid solid S1 was synthesized by a two step procedure. ...
DESIGN OF NEW NANOSTRUCTURES SYSTEMS WITH APPLICATIONS IN THE FIELD OF RECOGNITION AND DIAGNOSIS

Ribes Momparler, Ángela (Universitat Politècnica de València, 2018-09-10)

La presente tesis doctoral titulada "Design of new nanostructured systems with applications in the field of recognition and diagnosis" está enfocada en el diseño y síntesis de nuevos materiales híbridos con función de ...
Design of oligonucleotide-capped mesoporous silica nanoparticles for the detection of miRNA-145 by duplex and triplex formation

Ribes, Àngela; Santiago Felipe, Sara; Aviñó, Anna; Candela-Noguera, Vicente; Eritja, Ramón; Sancenón Galarza, Félix; Martínez-Máñez, Ramón; Aznar, Elena (Elsevier, 2018-12)

[EN] The development of new strategies to detect microRNAs (miRNAS) has become an important challenge in thebiomedical ¿eld. We report herein the use of oligonucleotide-gated silica nanoparticles for the detection ofmiRNA-145. ...
Design of smart scaffolds for the treatment and prevention of bone infection

Polo Aguado, Lorena (Universitat Politècnica de València, 2018-10-30)

La presente tesis doctoral, titulada "Diseño de scaffolds inteligentes para la prevención y tratamiento de la infección ósea", se centra en el desarrollo de materiales híbridos orgánico-inorgánicos capaces de realizar una ...
Development and Testing of a New Instrument for Researching on Cancer Treatment Technologies Based on Magnetic Hyperthermia

García, O.; Moreno-Arrones, N.; Cuesta, A.B.; Gutierrez, A.; Alou, P.; Oliver, J.A.; Cobos, J.A.; Uceda, J.; Aznar, Elena; Martínez-Máñez, Ramón; Sánchez, C.; Casanova, O.E.; Serrano, J.J.; FRANCISCO DEL POZO (Institute of Electrical and Electronics Engineers (IEEE), 2016-03)

A power electronics circuit allows the generation of high-frequency magnetic field that can be used to increase the temperature of cancer cells previously invaded with the magnetic nanoparticles. The circuit designed for ...
Diseño de materiales híbridos orgánico-inorgánicos para el reconocimiento de miRNA145

Candela Noguera, Vicente (Universitat Politècnica de València, 2016-06-06)

[ES] Este trabajo final de máster surge de la necesidad de desarrollar un sistema de detección sencillo y rápido para la detección de miRNAs como una estrategia general que podría ser muy útil en aplicaciones biomédicas. ...
Diseño de sistemas de comunicación química nanopartícula-levadura empleando materiales con puertas moleculares

Rincón Martínez, Paola (Universitat Politècnica de València, 2018-10-17)

[ES] La nanotecnología está resultando ser una herramienta útil para el diseño de sistemas avanzados que permiten el desarrollo de nuevas funciones antes difícilmente imaginables. Sin embargo, aún existen áreas por explorar, ...