[ES] Los avances en tecnologías de secuenciación masiva han dado lugar al desarrollo de la transcriptómica por secuenciación, que permite analizar la expresión de genes e isoformas. El laboratorio de Genómica de la Expresión ...

[EN] As the use of RNA-seq has popularized, there is an increasing consciousness of the importance of experimental design, bias removal, accurate quantification and control of false positives for proper data analysis. We ...

[EN] Purpose Locally advanced non-small cell lung cancer (LA-NSCLC) is frequently treated with chemoradiotherapy (CRT). Despite the efforts, long-term outcomes are poor, and novel therapies have been introduced to improve ...

[EN] Pneumocystis species are ascomycete fungi adapted to live inside the lungs of mammals. These ascomycetes show extensive stenoxenism, meaning that each species of Pneumocystis infects a single species of host. Here, ...

[EN] Multi-omic studies combine measurements at different molecular levels to build comprehensive models of cellular systems. The success of a multi-omic data analysis strategy depends largely on the adoption of adequate ...

[ES] Los avances en tecnologías de secuenciación masiva permiten obtener datos de expresión génica y también de sus elementos reguladores y productos. Integrar estas medidas multiómicas en un modelo estadístico que explique ...

[EN] In recent years the omics disciplines have made their way across a wider spectrum of research groups, thus leading to the generation of multi-omics data sets in a great number of studies. While traditional omics ...

[EN] Motivation: The widespread adoption of RNA-seq to quantitatively measure gene expression has increased the scope of sequencing experimental designs to include time-course experiments. maSigPro is an R package ...

[EN] Background: The development of high-throughput omics technologies enabled genome-wide measurements of the activity of cellular elements and provides the analytical resources for the progress of the Systems ...

[EN] Background: The integrative analysis of multiple genomics data often requires that genome coordinates-based signals have to be associated with proximal genes. The relative location of a genomic region with respect ...