[ES] Los avances en tecnologías de secuenciación masiva han dado lugar al desarrollo de la transcriptómica por secuenciación, que permite analizar la expresión de genes e isoformas. El laboratorio de Genómica de la Expresión ...

[EN] As the use of RNA-seq has popularized, there is an increasing consciousness of the importance of experimental design, bias removal, accurate quantification and control of false positives for proper data analysis. We ...

[ES] El enfoque multiómico está ganando terreno en el campo de la biología de sistemas, ya que permite estudiar aspectos complementarios del funcionamiento de un sistema biológico. Sin embargo, la integración de datos ...

[ES] Los avances en tecnologías de secuenciación masiva permiten obtener datos de expresión génica y también de sus elementos reguladores y productos. Integrar estas medidas multiómicas en un modelo estadístico que explique ...

[EN] In recent years the omics disciplines have made their way across a wider spectrum of research groups, thus leading to the generation of multi-omics data sets in a great number of studies. While traditional omics ...

[EN] Motivation: The widespread adoption of RNA-seq to quantitatively measure gene expression has increased the scope of sequencing experimental designs to include time-course experiments. maSigPro is an R package ...

[EN] Background: The development of high-throughput omics technologies enabled genome-wide measurements of the activity of cellular elements and provides the analytical resources for the progress of the Systems ...

[EN] Background: The integrative analysis of multiple genomics data often requires that genome coordinates-based signals have to be associated with proximal genes. The relative location of a genomic region with respect ...

[EN] Non-coding RNA transcripts such as microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) are important genetic regulators. However, the functions of many of these transcripts are still not clearly understood. Recently, ...

[EN] High-throughput transcriptome studies are breaking new ground to investigate the responses that organisms deploy in alternative environments. Nevertheless, much remains to be understood about the genetic basis of ...