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Browsing by Author "Lozano Torres, Beatriz"

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Browsing by Author "Lozano Torres, Beatriz"

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    A versatile drug delivery system targeting senescent cells 
    Muñoz-Espín, Daniel; Rovira, M.; Galiana, Irene; Giménez Morales, Cristina; Lozano-Torres, Beatriz; Páez Ribes, M.; LLanos, Susana; Chaib, Selim; Muñoz-Martín, M.; Ucero, Alvaro C.; Garaulet, G.; Mulero, F.; Dann, S.G.; VanArsdale, T.; Shields, D.J.; Bernardos Bau, Andrea; Murguía, Jose R.; Martínez-Máñez, Ramón (EMBO, 2018-09)
    [EN] Senescent cells accumulate in multiple aging-associated diseases, and eliminating these cells has recently emerged as a promising therapeutic approach. Here, we take advantage of the high lysosomal beta-galactosidase ...
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    An OFF-ON Two-Photon Fluorescent Probe for Tracking Cell Senescence in Vivo 
    Lozano-Torres, Beatriz; Galiana, Irene; Rovira, M.; Garrido-García, Eva María; Chaib, Selim; Bernardos Bau, Andrea; Muñoz-Espín, Daniel; Serrano, M.; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (American Chemical Society, 2017)
    [EN] A naphthalimide-based two-photon probe (AHGa) for the detection of cell senescence is designed. The probe contains a naphthalimide core, an L-histidine methyl ester linker, and an acetylated galactose bonded to one ...
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    Anilinopyridine metal complexes for the selective chromogenic sensing of cyanide anion 
    Lozano-Torres, Beatriz; Marcos Martínez, María Dolores; Pardo Vicente, María Teresa; Sancenón Galarza, Félix; Martínez-Máñez, Ramón; Rurack, K. (Taylor & Francis, 2018)
    [EN] Probe 1, which contains an anilinopyridine chromophore and an aza-oxa macrocyclic subunit, presented an absorption band centered at 340 nm in acetonitrile. Addition of Fe(III), Cr(III) and Hg(II) induced the growth ...
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    Chromogenic and Fluorogenic Probes for the Detection of Illicit Drugs 
    Garrido-García, Eva María; Pla, Luis; Lozano-Torres, Beatriz; El Sayed Shehata Nasr, Sameh; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (John Wiley & Sons, 2018-05)
    [EN] The consumption of illicit drugs has increased exponentially in recent years and has become a problem that worries both governments and international institutions. The rapid emergence of new compounds, their easy ...
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    Mesoporous silica materials for controlled delivery based on enzymes 
    Llopis-Lorente, Antoni; Lozano-Torres, Beatriz; Bernardos Bau, Andrea; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (The Royal Society of Chemistry, 2017)
    [EN] This review summarises examples of capped mesoporous silica materials for controlled delivery that use enzymes as external triggers or functional components of the gating ensemble.
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    Nanosensor for Sensitive Detection of the New Psychedelic Drug 25I-NBOMe 
    Garrido-García, Eva María; Alfonso-Navarro, María; Díaz de Greñu-Puertas, Borja; Lozano-Torres, Beatriz; Parra Álvarez, Margarita; Gaviña, Pablo; Marcos Martínez, María Dolores; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (John Wiley & Sons, 2020-03-02)
    [EN] This work reports the synthesis, characterization, and sensing behavior of a hybrid nanodevice for the detection of the potent abuse drug 25I-NBOMe. The system is based on mesoporous silica nanoparticles, loaded with a ...
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    Overview of the Evolution of Silica-Based Chromo-Fluorogenic Nanosensors 
    Pla, Luis; Lozano-Torres, Beatriz; Martínez-Máñez, Ramón; Sancenón Galarza, Félix; Ros-Lis, José Vicente (MDPI AG, 2019-11-23)
    [EN] This review includes examples of silica-based, chromo-fluorogenic nanosensors with the aim of illustrating the evolution of the discipline in recent decades through relevant research developed in our group. Examples ...
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    Pseudorotaxane capped mesoporous silica nanoparticles for 3,4-methylenedioxymethamphetamine (MDMA) detection in water 
    Lozano-Torres, Beatriz; Pascual, Lluís; Bernardos Bau, Andrea; Marcos Martínez, María Dolores; Jeppesen, Jan Oskar; Salinas Soler, Yolanda; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (The Royal Society of Chemistry, 2017-03-28)
    [EN] Mesoporous silica nanoparticles loaded with fluorescein and capped by a pseudorotaxane, formed between a naphthalene derivative and cyclobis(paraquat-p-phenylene) (CBPQT(4+)), were used for the selective and sensitive ...
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    Selective and Sensitive Chromogenic Detection of Trivalent Metal Cations in Water 
    Lozano-Torres, Beatriz; El Sayed Shehata Nasr, Sameh; Costero, Ana M.; Gil, Salvador; Parra, Margarita; Martínez-Máñez, Ramón; Sancenón Galarza, Félix (Chemical Society of Japan, 2016-04-15)
    [EN] An azopyridine derivative for the selective and sensitive chromogenic detection of trivalent letal cations in water is described.