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Browsing by Author "Marin Paya, Juan Carlos"

Now showing items 1-6 of 6

3D Culture o Multiple Myeloma Cell Line Using Microgel Environments

Marin Paya, Juan Carlos (Universitat Politècnica de València, 2021-06-03)

[ES] El mieloma múltiple es una neoplasia hematológica caracterizada por una expansión descontrolada de células plasmáticas monoclonales (mPCs) en medula ósea que producen, en la mayoría de los casos, un componente monoclonal ...
Biomimetic 3D environment based on microgels as a model for the generation of drug resistance in multiple myeloma

Marín-Payá, Juan Carlos; Díaz-Benito, Blanca; Amaro Martins, Luis; Clara Trujillo, Sandra; Cordón, Lourdes; Lanceros-Méndez, Senentxu; Gallego Ferrer, Gloria; Sempere, Amparo; Gómez Ribelles, José Luís (MDPI AG, 2021-12)

[EN] The development of three-dimensional environments to mimic the in vivo cellular response is a problem in the building of disease models. This study aimed to synthesize and validate three-dimensional support for culturing ...
Biomimetic 3D Environment Based on Microgels as a Model for the Generation of Drug Resistance in Multiple Myeloma

Marin Paya, Juan Carlos; Díaz Benito, Blanca; Amaro Martins, Luis; Clara Trujillo, Sandra; Cordón, Lourdes; Lanceros-Mendez, Senentxu; Gallego Ferrer, Gloria; Sempere, Amparo; Gómez Ribelles, José Luís (Universitat Politècnica de València, 2021-12-14)

The development of three-dimensional environments to mimic the in vivo cellular response is a problem in the building of disease models. This study aimed to synthesize and validate three-dimensional support for culturing ...
Biomimetic microspheres for 3D mesenchymal stem cell culture and characterization

Clara-Trujillo, Sandra; Marin-Paya, Juan Carlos; Cordón, Lourdes; Sempere, Amparo; Gallego Ferrer, Gloria; Gómez Ribelles, José Luís (Elsevier, 2019-05-01)

[EN] Stem cells reside in niches, specialized microenvironments that sustain and regulate their fate. Extracellular matrix (ECM), paracrine factors or other cells are key niche regulating elements. As the conventional 2D ...
Producción y caracterización de microesferas de alginato funcionalizadas con colágeno y ácido hialurónico como soporte tridimensional para el cultivo de células de mieloma múltiple

Díaz Benito, Blanca (Universitat Politècnica de València, 2019-09-02)

[ES] El mieloma múltiple (MM) es una neoplasia hematológica caracterizada por una expansión clonal de las células plasmáticas (CPs). Los cultivos 2D convencionales se ha visto que no consiguen reproducir el desarrollo ...
Protein-Functionalized Microgel for Multiple Myeloma Cells' 3D Culture

Marin-Paya, Juan Carlos; Clara-Trujillo, Sandra; Cordón, Lourdes; Gallego Ferrer, Gloria; Sempere, Amparo; Gómez Ribelles, José Luís (MDPI AG, 2022-11)

[EN] Multiple myeloma is a hematologic neoplasm caused by an uncontrolled clonal proliferation of neoplastic plasma cells (nPCs) in the bone marrow. The development and survival of this disease is tightly related to the ...