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Browsing by Author "Gonzalez Álvarez, Isabel"

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Browsing by Author "Gonzalez Álvarez, Isabel"

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    A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability 
    Rodríguez Berna, Guillermo; Mangas Sanjuan, Victor; Gonzalez Alvarez, Marta; Gonzalez Álvarez, Isabel; Garcia Gimenez, Jose Luis; Díaz Cabañas, Mª José; Bermejo, Marival; Corma Canós, Avelino (Elsevier, 2014-08-18)
    Oral administration of camptothecin (Cm) derivatives and other antitumoral agents is being actively developed in order to improve the quality of life of patients with cancer. Though several lipophilic derivatives of CPT ...
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    Semisynthesis, Cytotoxic Activity, and Oral Availability of New Lipophilic 9-Substituted Camptothecim Derivatives 
    Rodríguez Berna, Guillermo; Díaz Cabañas, Mª José; Mangas Sanjuan, Víctor; Gonzalez Alvarez, Marta; Gonzalez Álvarez, Isabel; Abasolo, Ibane; Simo Schwartz, Jr.; Bermejo, Marival; Corma Canós, Avelino (American Chemical Society, 2013-05-28)
    Despite that 9-substituted camptothecins are promising candidates in cancer therapy, the limited accessibility to this position has reduced the studies of these derivatives to a few standard modifications. We report herein ...