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Browsing by Author "Jiménez Molero, María Consuelo"

Now showing items 21-40 of 69

Estudio fotofísico y fotoquímico del 4-Trifluorometil-1-Naftol

Molins Molina, Óscar (Universitat Politècnica de València, 2015-07-17)
Estudio fotoquímico y fotofísico del ansiolítico clordiazepóxido y su metabolito demoxepam

Moreno Roig, Gema (Universitat Politècnica de València, 2021-10-21)

[ES] El clordiazepóxido es un fármaco que pertenece al grupo de las benzodiazepinas y se utiliza para tratar problemas asociados a la ansiedad. En relación a la biotransformación de fármacos, esta se asocia a una mayor ...
Estudio fotoquímico y fotofísico del antiinflamatorio flurbiprofeno y sus derivados de interés fotobiológico

Gil Flores, Lorena (Universitat Politècnica de València, 2015-06-12)

Consulta en la Biblioteca ETSI Industriales (Riunet)
Estudio fotoquímico y fotofísico del fármaco sulfasalazina en medios biomiméticos

García Gimeno, Belén (Universitat Politècnica de València, 2021-10-06)

[ES] La sulfasalazina (SSZ) es un fármaco empleado para el tratamiento de la artritis reumatoide, la colitis ulcerosa y la enfermedad de Crohn. Entre otras reacciones adversas asociadas a este fármaco se han descrito los ...
Estudio fotoquímico y fotofísico del fármaco Sulindaco y sus metabolitos en medios biológicos

Calero Pons, Elena (Universitat Politècnica de València, 2019-09-04)

[ES] En este trabajo se ha estudiado la fotorreactividad del fármaco sulindaco (SLD), que es un antiinflamatorio no esteroideo (AINE), en disolución y en presencia de proteínas. También se ha investigado la fotorreactividad ...
Excited state interactions between flurbiprofen and tryptophan in drug-protein complexes and in model dyads. Fluorescence studies from the femtosecond to the nanosecond time domains

Vayá Pérez, Ignacio; Bonancía Roca, Paula; Jiménez Molero, María Consuelo; Markovitsi, Dimitra; Gustavsson, Thomas; Miranda Alonso, Miguel Ángel (Royal Society of Chemistry, 2013)

We report here on the interaction dynamics between flurbiprofen (FBP) and tryptophan (Trp) covalently linked in model dyads and in a complex of FBP with human serum albumin (HSA) probed by time-resolved fluorescence ...
Excited State Interactions in Flurbiprofen-Tryptophan dyads

Vayá Pérez, Ignacio; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel (American Chemical Society, 2007)

[EN] Fluorescence and laser-flash photolysis measurements have been performed on two pairs of diastereomeric dyads that contain the nonsteroidal anti-inflammatory drug (S)- or (R)-flurbiprofen (FBP) and (S)-tryptophan ...
Excited-state interactions in diastereomeric flurbiprofen-thymine dyads

Bonancía Roca, Paula; Vayá Pérez, Ignacio; Climent Olmedo, María José; Gustavsson, Thomas; Markovitsi, Dimitra; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel (American Chemical Society, 2012-09-06)

Excited-state interactions between (S)- or (R) fluorescence (S)- or (R)-FBP) and thymidine (dThd) covalently linked in dyads 1 or 2 have been investigated. In both dyads, the only emitting species is (FBP)-F-1*, but with ...
Experimental and Theoretical Studies on the Radical-Cation-Mediated Imino-Diels_Alder Reaction

Pérez Ruiz, Raul; Domingo, Luis R; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel (American Chemical Society, 2011)

[EN] The feasibility of an electron transfer imino-Diels Alder reaction betweenN-benzylideneaniline and arylalkenes in the presence of a pyrylium salt as a photosensitizer has been demonstrated by a combination of product ...
Fluorescent-Labeled Octasilsesquioxane Nanohybrids as Potential Materials for Latent Fingerprinting Detection

Dare, Enock O.; Vendrell-Criado, Victoria; Jiménez Molero, María Consuelo; Pérez-Ruiz, Raúl; Díaz Díaz, David (John Wiley & Sons, 2020-10-15)

[EN] The recent demand for fluorescent-labeled materials (FLMs) in forensic security concepts such as latent fingerprints (LFs) that encode information for anti-counterfeiting and encryption of confidential data makes ...
Fotoquímica de compuestos heteroaromáticos tricíclicos en medios biomiméticos

Limones Herrero, Daniel (Universitat Politècnica de València, 2016-01-07)

[EN] The use of biomimetic media such as serum albumins (SAs), a1-acid glycloproteins (AAGs), cyclodextrins (CDs) and sodium dodecyl sulfate (SDS) micelles is combined with photophysical techniques (fluorescence (F) and ...
Hetero-cycloreversions Mediated by Photoinduced Electron Transfer

Pérez Ruiz, Raul; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel (American Chemical Society, 2014-04)

[EN] Discovered more than eight decades ago, the Diels-Alder (DA) cycloaddition (CA) remains one of the most versatile tools in synthetic organic chemistry. Hetero-DA processes are powerful methods for the synthesis of ...
Identification of a common recognition center for a photoactive non-steroidal antiinflammatory drug in serum albumins of different species

Molins-Molina, Oscar; Lence, Emilio; Limones-Herrero, Daniel; González-Bello, Concepción; Miranda Alonso, Miguel Ángel; Jiménez Molero, María Consuelo (Royal Society of Chemistry, 2019-01-07)

[EN] The non-steroidal anti-inflammatory drug (S)-carprofen (CPF) has been used as a photoactive probe to investigate the possible existence of a common recognition center in serum albumins (SAs) of different species. The ...
Influence of the spacer on the photoreactivity of flurbiprofen-tyrosine dyads

Vayá Pérez, Ignacio; Gustavsson, Thomas; Markovitsi, Dimitra; Miranda Alonso, Miguel Ángel; Jiménez Molero, María Consuelo (Elsevier, 2016-05-15)

[EN] The photoreactivity of diastereomeric dyads containing (S)- or (R)-flurbiprofen (FBP) and (S)-Tyr, either directly linked (1) or separated by a cyclic spacer (3) has been investigated. The main feature is a remarkable ...
Interacciones fármaco-proteína en estados excitados

Bueno Alejo, Carlos Javier (Universitat Politècnica de València, 2009-12-04)

Recientemente se ha usado la técnica de fotólisis de destello láser para el estudio de las interacciones fármaco/proteína, demostrando que el estado excitado triplete es muy sensible al medio que le rodea y que, por tanto, ...
Intraprotein formation of a long wavelength absorbing complex and inhibition of excited state deprotonation in a chiral hydroxybiphenyl

Bonancía Roca, Paula; Vayá Pérez, Ignacio; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel (American Chemical Society, 2012-12-27)

The two enantiomers of 2-(2-hydroxybiphenyl-4-yl)propanoic acid ((S)- and (R)-BPOH) have been selected as probes for human serum albumin (HSA). Photophysical characterization in the absence of protein led to emission maxima, ...
Investigation of metabolite-protein interactions by transient absorption spectroscopy and in silico methods

Limones Herrero, Daniel; Palumbo, Fabrizio; Vendrell Criado, Victoria; Andreu Ros, María Inmaculada; Lence, Emilio; González-Bello, Concepción; Miranda Alonso, Miguel Ángel; Jiménez Molero, María Consuelo (Elsevier, 2020-02-05)

[EN] Transient absorption spectroscopy in combination with in silico methods has been employed to study the interactions between human serum albumin (HSA) and the anti-psychotic agent chlorpromazine (CPZ) as well as its ...
Magnetic light and forbidden photochemistry: the case of singlet oxygen

Manjavacas, Alejandro; Fenollosa Esteve, Roberto; Rodriguez, Isabelle; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel; Meseguer Rico, Francisco Javier (The Royal Society of Chemistry, 2017)

[EN] Most optical processes occurring in nature are based on the well-known selection rules for opticaltransitions between electronic levels of atoms, molecules, and solids. Since in most situations themagnetic component ...
Mapping a protein recognition centre with chiral photoactive ligands. An integrated approach combining photophysics, reactivity, proteomics and molecular dynamics simulation studies

Limones-Herrero, Daniel; Pérez Ruiz, Raul; Lence, Emilio; Gonzalez-Bello, Concepcion; Miranda Alonso, Miguel Ángel; Jiménez Molero, María Consuelo (The Royal Society of Chemistry, 2017-04-01)

[EN] A multidisciplinary strategy to obtain structural information on the intraprotein region is described here. As probe ligands, (S)- and (R)-CPFMe (the methyl esters of the chiral drug carprofen) have been selected, ...
Mechanistic Studies on the Photoallergy Mediated by Fenofibric Acid: Photoreactivity with Serum Albumins

Vayá Pérez, Ignacio; Andreu Ros, María Inmaculada; Monje-López, Vicente Tomás; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel (American Chemical Society, 2016-01)

[EN] The photoreactivity of fenofibric acid (FA) in the presence of human and bovine serum albumins (HSA and BSA, respectively) has been investigated by steady-state irradiation, fluorescence, and laser flash photolysis ...