Rivero-Buceta, Eva María; VIDAURRE AGUT, CARLA MARIA; VERA DONOSO, CESAR DAVID; Benlloch Baviera, Jose María; MORENO MANZANO, VICTORIA; BOTELLA ASUNCION, PABLO(American Chemical Society, 2019-01-31)
[EN] Although docetaxel is currently broadly used in prostate cancer treatment, poor water solubility and systemic toxicity limit the dose and duration of therapy. In this context, although different nanoplatforms have ...
[EN] This work reports the applicability of reflux to the synthesis of Mo-V-Te-Nb-O metal oxide catalysts for the first time. The well-formed and defined orthorhombic M1 phase, i.e. Te2M20O57 (M = Mo, V, Nb), was found to ...
BOTELLA ASUNCION, PABLO; Rivero-Buceta, Eva María(Elsevier, 2017-02-10)
[EN] Twenty-(S)-camptothecin is a strongly cytotoxic molecule with excellent antitumor activity over a wide spectrum of human cancers. However, the direct formulation is limited by its poor water solubility, low plasmatic ...
Botella Asuncion, Pablo; Dejoz, A.; Abello, M. C.; Vazquez, M. I.; Arrua, L.; López Nieto, José Manuel(Elsevier, 2009-04-30)
[EN] Mo-V-X (X = Nb, Sb and/or Te) mixed oxides have been prepared by hydrothermal synthesis and heat-treated in N(2) at 450 degrees C or 600 degrees C for 2 h. The calcination temperature and the presence or absence of ...
Ivars Barceló, Francisco; Solsona Espriu, Benjamin Eduardo; Botella Asuncion, Pablo; Soriano Rodríguez, Mª Dolores; López Nieto, José Manuel(Elsevier, 2009-03-30)
[EN] Alkali metal-doped MoVSbO catalysts have been prepared by impregnation of a MoVSbO-mixed oxide (prepared previously by a hydrothermal synthesis) and finally activated at 500 or 600 degrees C in N-2. The catalysts have ...
De Santana Oliveira, Artur; Rivero-Buceta, Eva María; Vidaurre-Agut, Carla; Misturini, Alechania; Moreno, Victoria; Jorda Moret, Jose Luis; SASTRE NAVARRO, GERMAN IGNACIO; Castella Pergher, Sibele Berenice; BOTELLA ASUNCION, PABLO(Elsevier, 2020-12)
[EN] Post-synthetic modification of covalent organic frameworks (COFs) is strongly demanded in order to provide additional functionalities to their structures. However, the introduction of functional groups during the ...
[EN] The administration of cytotoxic drugs in classical chemotherapy is frequently limited by water solubility, low plasmatic stability, and a myriad of secondary effects associated with their diffusion to healthy tissue. ...
[EN] Here we report the design, synthesis and biological evaluation of surface-modified silica nanoparticles (SNP) for the delivery of camptothecin (CPT). Drug has been covalently linked to the nanoparticle through an ester ...
Botella Asuncion, Pablo; Corma Canós, Avelino; Quesada Vilar, Manuel(Royal Society of Chemistry, 2012)
[EN] A novel series of mesoporous silica materials has been developed by using non-ionic, biocompatible alkyl maltoside surfactants as organic structure directing agents and working under biomimetic conditions (e. g., room ...
Botella Asuncion, Pablo; Corma Canós, Avelino; CARR, ROBERT H.; MITCHELL, CHRIS J.(Elsevier, 2011)
Delaminated materials ITQ-2, ITQ-6 and ITQ-18 are very efficient catalysts of zeolitic nature for the synthesis of diamino diphenyl methane (DADPM), the polyamine precursor in the production of MDI for polyurethanes. The ...