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Browsing by Author "Gomis-Tena Dolz, Julio"

RiuNet: Institutional repository of the Polithecnic University of Valencia

Browsing by Author "Gomis-Tena Dolz, Julio"

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    Dispositivo para la determinación de la tasa metabólica humana 
    Belloch Ramos, María Amparo (Universitat Politècnica de València, 2014-02-14)
    Consulta en la Biblioteca ETSI Industriales (7501)
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    Electrónica industrial: problemas resueltos 
    Gomis-Tena Dolz, Julio; Figueres Amorós, Emilio; Garcerá Sanfeliú, Gabriel (Editorial Universitat Politècnica de València, 2019-06-11)
    La Electrónica Industrial, o al menos así se entiende desde titulaciones como la de Ingeniero Industrial (I.I.) o la de Ingeniero en Automática y Electrónica Industrial (I.A.E.I.), versa sobre el estudio de las topologías ...
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    In silico assessment of drug safety in human heart applied to late sodium current blockers 
    Trénor Gomis, Beatriz Ana; Gomis-Tena Dolz, Julio; Cardona Urrego, Karen Eliana; Romero Pérez, Lucia; Rajamani, Sridharan; Belardinelli, Luiz; Giles, Wayne R.; Saiz Rodríguez, Francisco Javier (Landes Bioscience, 2013-07-01)
    Drug-induced action potential (AP) prolongation leading to Torsade de Pointes is a major concern for the development of anti-arrhythmic drugs. Nevertheless the development of improved anti-arrhythmic agents, some of which ...
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    In Silico QT and APD Prolongation Assay for Early Screening of Drug-Induced Proarrhythmic Risk 
    Romero Pérez, Lucia; Cano-García, Jordi; Gomis-Tena Dolz, Julio; Trenor Gomis, Beatriz Ana; Sanz, Ferran; Pastor, Manuel; Saiz Rodríguez, Francisco Javier (American Chemical Society, 2018)
    [EN] Drug-induced proarrhythmicity is a major concern for regulators and pharmaceutical companies. For novel drug candidates, the standard assessment involves the evaluation of the potassium hERG channels block and the in ...
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    InSilico Classifiers for the Assessment of Drug Proarrhythmicity 
    Llopis-Lorente, Jordi; Gomis-Tena Dolz, Julio; Cano, Jordi; Romero Pérez, Lucia; Saiz Rodríguez, Francisco Javier; Trenor Gomis, Beatriz Ana (American Chemical Society, 2020-10-26)
    [EN] Drug-induced torsade de pointes (TdP) is a life-threatening ventricular arrhythmia responsible for the withdrawal of many drugs from the market. Although currently used TdP risk-assessment methods are effective, they ...
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    Nuevo sistema de amplificación de señal ECG para ser utilizado en textiles inteligentes 
    Lladró Folgado, José (Universitat Politècnica de València, 2015-01-30)
    El proyecto realizado es un dispositivo inalámbrico capaz de captar las señales electrocardiográficas (ECG) y enviarlas a un ordenador donde podrán ser visualizadas, empleando como pieza fundamental el front – end ADS1296 ...
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    Tx, TqNet and Ttriang Values 
    Llopis Lorente, Jordi; Gomis-Tena Dolz, Julio; Cano García, Jordi; Romero Pérez, Lucia; Saiz Rodríguez, Francisco Javier; Trénor Gomis, Beatriz Ana (Universitat Politècnica de València, 2020-02-14)
    This repository contains the Matlab functions used in [1] and six Excel files named “Tx matrix KrKsCaL.xlsx”, “Tx matix KrNaLCaL.xlsx”, “TqNet matrix KrKsCaL.xlsx”, “TqNet matrix KrNaLCaL.xlsx”, "Ttirang matrix KrKsCaL.xlsx" ...
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    When Does the IC50 Accurately Assess the Blocking Potency of a Drug? 
    Gomis-Tena Dolz, Julio; Brown, Brandon M.; Cano, Jordi; Trenor Gomis, Beatriz Ana; Yang, Pei-Chi; Saiz Rodríguez, Francisco Javier; Clancy, Colleen E.; Romero Pérez, Lucia (American Chemical Society, 2020-03-23)
    [EN] Preclinical assessment of drug-induced proarrhythmicity is typically evaluated by the potency of the drug to block the potassium human ether-a-go-go-related gene (hERG) channels, which is currently quantified by the ...