Caffrey, Brian E.; Williams, Tom A.; Jiang, Xiaowei; Toft, Christina; Hokamp, Karsten; Fares Riaño, Mario Ali(Public Library of Science, 2012-04)
Functional divergence is the process by which new genes and functions originate through the modification of existing ones.
Both genetic and environmental factors influence the evolution of new functions, including gene ...
Luisi, P; Alvarez-Ponce, D; Pybus, M; Fares Riaño, Mario Ali; Bertranpetit, J; Laayouni, H(Oxford University Press (OUP), 2015-04)
Genes vary in their likelihood to undergo adaptive evolution. The genomic factors that determine adaptability, however, remain poorly understood. Genes function in the context of molecular networks, with some occupying ...
[EN] Biological systems are resistant to perturbations caused by the environment and by the intrinsic noise of the system. Robustness to mutations is a particular aspect of robustness in which the phenotype is resistant ...
Mattenberger, Florian; Sabater-Muñoz, B.; Toft, C.; Fares Riaño, Mario Ali(The Genetics Society of America, 2017-01)
[EN] Gene and genome duplication are the major sources of biological innovations in plants and animals. Functional and transcriptional divergence between the copies after gene duplication has been considered the main driver ...
[EN] The cell central metabolism has been shaped throughout evolutionary times when facing challenges from the availability of resources. In the budding yeast, Saccharomyces cerevisiae, a set of duplicated genes originating ...
Sabater-Muñoz, Beatriz; Mattenberger, Florian; Fares Riaño, Mario Ali; Toft, Christina(American Society for Microbiology, 2020-08)
[EN] Ethanol is the main by-product of yeast sugar fermentation that affects
microbial growth parameters, being considered a dual molecule, a nutrient and a
stressor. Previous works demonstrated that the budding yeast arose ...