Serrano Requena, Sara(Universitat Politècnica de València, 2021-10-08)
[ES] Las patologías que se derivan en el sistema nervioso llevan asociadas la dificultad de regeneración del propio tejido, especialmente cuando se habla del Sistema Nervioso Central (SNC). Es debido a esta problemática ...
García Jiménez, Irene(Universitat Politècnica de València, 2020-09-08)
[ES] La problemática asociada a las patologías del sistema nervioso viene del limitado potencial de regeneración de los tejidos nerviosos, y especialmente del SNC. Las lesiones en estos tejidos suponen un importante problema ...
Villa Sánchez, Camila Alejandra(Universitat Politècnica de València, 2021-09-17)
[EN] Central and peripheral nervous system injuries such as nerve injuries and spinal cord injury are
diseases with a high incidence today due to trauma situations, the consequences of these
traumas are high in the quality ...
Lapeña Luzón, Tamara(Universitat Politècnica de València, 2017-09-05)
[ES] Las lesiones de la médula espinal son un problema que presenta múltiples consecuencias a
nivel sanitario, social y económico. Estas alteraciones provocan una pérdida de la función
motora y sensorial por debajo de ...
[EN] Objective: To assemble a biohybrid cardiac patch consisting of a large (5x5 cm) elastomer scaffold whose pores are filled with a self-assembling peptide (SAP) gel entrapping adipose stem cells, to be used as a novel ...
[EN] Ischemia produced as a result of myocardial infarction might cause moderate or severe tissue death. Studies under development propose grafting stem cells into the affected area and we hypothesize that this mechanism ...
Chachques, Juan Carlos; Lila, Nermine; Soler Botija, Carolina; Martínez-Ramos, Cristina; Vallés Lluch, Ana; Autret, Gwennhael; Perier, Marie-Cecile; Mirochnik, Nicolas; Monleón Pradas, Manuel; Bayes-Genis, Antoni; Semino, Carlos E.(Oxford University Press, 2020-03)
[EN] OBJECTIVES: Prevention of postischaemic ventricular dilatation progressing towards pathological remodelling is necessary to decrease ventricular wall deterioration. Myocardial tissue engineering may play a therapeutic ...
[EN] Nerve regeneration is a slow process that needs to be guided for distances greater than 5 mm. For this reason, different strategies are being studied to guide axonal growth and accelerate the axonal growth rate. In ...
[EN] A procedure to obtain electrospun mats of hyaluronic acid (HA) stable in aqueous media in one single step has been developed. It consists in combining an HA solution with a divinyl sulfone one as cross-linker in a ...
Bolaina-Lorenzo, Ena; Martínez-Ramos, Cristina; Monleón Pradas, Manuel; Herrera-Kao, Wilberth; Cauich-Rodríguez, Juan V; Cervantes-Uc, José M(IOP Publishing, 2017)
[EN] Electrospun polycaprolactone (PCL)/chitosan (CH) blend scaffolds with different CH weight ratios were prepared to study the effect of scaffold composition on its physicochemical and biological properties. Scanning ...
[EN] Injuries to the nervous system that involve the disruption of axonal pathways are devastating to the individual and require specific tissue engineering strategies. Here we analyse a cells-biomaterials strategy to ...
Gregorio Collazo, Manuel(Universitat Politècnica de València, 2022-09-05)
[ES] El proceso de regeneración de tractos neurales formados por axones puede ser asistido mediante biomateriales (scaffolds) que sirvan de soporte de crecimiento y guía estructural. En el trabajo se realizará un estudio ...
García Chamorro, Javier(Universitat Politècnica de València, 2022-09-05)
[ES] El proceso de regeneración de tractos axonales puede ser asistido mediante biomateriales (scaffolds) que sirvan de soporte de crecimiento y guía estructural, y puede ser estimulado mediante aplicación de corrientes ...
Cerqueira, Andreia; Araújo-Gomes, Nuno; Zhang, Yang; van den Beucken, Jeroen J. J. P.; Martínez-Ramos, Cristina; Ozturan, Seda; Izquierdo, Raúl; Muriach, Maria; Romero-Cano, Ricard; Baliño, Pablo; Romero-Gavilán, Francisco J.(John Wiley & Sons, 2021-09)
[EN] The immune system plays a crucial role in determining the implantation outcome, and macrophages are in the frontline of the inflammatory processes. Further, cellular oxidative stress resulting from the material ...
Lecca Villacorta, Leandro(Universitat Politècnica de València, 2018-09-19)
[ES] Las lesiones del sistema nervioso provocan desórdenes neurológicos de naturaleza cognitiva, motora
y psíquica que afectan a millones de personas de todo el mundo. Las lesiones del sistema
nervioso periférico (SNP) ...
Vallés Lluch, Ana; Arnal Pastor, María Pilar; Martínez-Ramos, Cristina; Vilariño, Guillermo; Vikingsson, Line; Monleón Pradas, Manuel(Institute of Electrical and Electronics Engineers, 2013)
[EN] Scaffolds of poly(ethyl acrylate) (PEA) with interconnected cylindrical orthogonal pores filled with a self-assembling peptide (SAP) gel are here proposed as patches for infarcted tissue regeneration. These combined ...
[EN] Myocardial tissue lacks the ability to regenerate itself significantly following a myocardial infarction. Thus, new strategies that could compensate this lack are of high interest. Cardiac tissue engineering (CTE) ...
[EN] Background Calcium (Ca) is a well-known element in bone metabolism and blood coagulation. Here, we investigate the link between the protein adsorption pattern and the in vivo responses of surfaces modified with calcium ...
[EN] The interior of tissue engineering scaffolds must be vascularizable and allow adequate nutrients perfusion in order to ensure the viability of the cells colonizing them. The promotion of rapid vascularization of ...
[EN] Hydrogels have widely been proposed lately as strategies for neural tissue regeneration, but there are still some issues to be solved before their efficient use in tissue engineering of trauma, stroke or the idiopathic ...