Miró, Paula; Gomez-Mendoza, Miguel; SASTRE NAVARRO, GERMAN IGNACIO; Cuquerella Alabort, Maria Consuelo; Miranda Alonso, Miguel Ángel; Marín García, Mª Luisa(John Wiley & Sons, 2019-05-17)
[EN] Benzophenone (BP) and drugs containing the BP chromophore, such as the non-steroidal anti-inflammatory drug ketoprofen, have been widely reported as DNA photo-sensitizers through triplet-triplet energy transfer (TTET). ...
Vayá Pérez, Ignacio; Andreu Ros, María Inmaculada; Monje-López, Vicente Tomás; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel(American Chemical Society, 2016-01)
[EN] The photoreactivity of fenofibric acid (FA) in the presence of human and bovine serum albumins (HSA and BSA, respectively) has been investigated by steady-state irradiation, fluorescence, and laser flash photolysis ...
Dhakshinamoorthy, Amarajoth; Navalón Oltra, Sergio; Alvaro Rodríguez, Maria Mercedes; García Gómez, Hermenegildo(Wiley-VCH Verlag, 2012-01-09)
[EN] The Fenton reaction (the generation of hydroxyl radicals from hydrogen peroxide) is the most useful method for degradation of organic pollutants in aqueous solution at moderate concentrations. In this Review we summarize ...
Pavanello, Alice(Universitat Politècnica de València, 2022-12-30)
[ES] La demanda de agua y la contaminación del agua son dos problemas ligados no solo de los últimos años sino también para el futuro. Mucho se ha hecho en el pasado para eliminar los contaminantes emergentes (CEC) de los ...
Aparici Espert, María Isabel(Universitat Politècnica de València, 2018-07-13)
El objetivo principal de esta tesis es contrastar el papel de dichos compuestos 1,3-dicarbonilicos como agentes que dañan el ADN con respecto a su potencial fotoprotector.
Primero, 5,6-dihidropirimidinas han sido ...
Alvaro Rodríguez, Maria Mercedes; Ferrer Ribera, Rosa Belén; García Gómez, Hermenegildo; Hashimoto, Shuichi; Hiratsuka, Masahiro; Asahi, Tsuyoshi; Masuhara, Hiroshi(Wiley-VCH Verlag, 2014-07)
Persistent radical cations can be generated in V∝PMO, a periodic mesoporous organosilica incorporating a viologen in its silicate framework. Photoexcitation of V∝PMO forms a geminate viologen–halide ion pair that can undergo ...
Pérez Ruiz, Raul; Molins-Molina, Oscar; Lence, Emilio; González-Bello, Concepción; Miranda Alonso, Miguel Ángel; Jiménez Molero, María Consuelo(American Chemical Society, 2018-11-02)
[EN] Latent electrophiles are nowadays very attractive chemical entities for drug discovery, as they are unreactive unless activated upon binding with the specific target. In this work, the utility of 4-trifluoromethyl ...
Ferrer Ribera, Rosa Belén; Rogez, Guillaume; Credi, Alberto; Ballardini, Roberto; Gandolfi, Maria Teresa; Balzani, Vincenzo; Liu, Yi; Tseng, Hsian-Rong; Stoddart, J. Fraser(National Academy of Sciences, 2006-07-28)
We report the design, bottom-up construction, characterization, and operation of a supramolecular system capable of mimicking the function played by a macroscopic electrical extension cable. The system is made up of a ...
Lizondo Aranda, Paloma(Universitat Politècnica de València, 2022-11-14)
[ES] Los estudios sobre los daños en el ADN se han incrementado en las últimas décadas con el fin de profundizar en su implicación en la aparición del cáncer. Entre el gran número de lesiones del ADN, los aductos de tipo ...
Vendrell Criado, Victoria; Rodríguez Muñiz, Gemma María; Cuquerella Alabort, Maria Consuelo; Lhiaubet, Virginie Lyria; Miranda Alonso, Miguel Ángel(Wiley-VCH Verlag, 2013-06-17)
A (photo)sensitive subject: Combined agarose gel electrophoresis and photochemical studies show that 5-methyl-2-pyrimidone (see picture), the main chromophore of (6-4) photoproducts, behaves as a DNA photosensitizer. These ...
Andreu Ros, María Inmaculada; Neshchadin, Dmytro; Rico Inglada, Enrique; Griesser, Markus; Samadi, Abdelouahid; Morera Bertomeu, Isabel María; Gescheidt, Georg; Miranda Alonso, Miguel Ángel(Wiley-VCH Verlag, 2011-07-26)
A thorough mechanistic study has been performed on the reaction between benzophenone (BZP) and a series of 1,4-dienes, including 1,4-cyclohexadiene (CHD), 1,4-dihydro-2-methylbenzoic acid (MBA), 1,4-dihydro-1,2-dimethylbenzoic ...
Rodríguez Muñiz, Gemma María; Marín García, Mª Luisa; Lhiaubet, Virginie Lyria; Miranda Alonso, Miguel Ángel(Wiley-VCH Verlag, 2012-06-25)
DNA damage: The reactivity of HO. with silylated 2¿-deoxyribonucleosides was investigated in acetonitrile by means of a time-resolved technique. The obtained rate constants were in general slightly lower than those reported ...
Martínez-Haya, Rebeca; Marzo, L.; König, B.(The Royal Society of Chemistry, 2018-10-21)
[EN] A visible light mediated De Mayo reaction between 1,3-diketones and styrenes following a [2+2] cycloaddition pathway via a photosensitization mechanism gives access to 1,5-diketones. The reaction has been applied to ...
The mechanism responsible for the remarkable photomutagenicity of fluoroquinolone (FQ) antibiotics remains unknown. For this reason, it was considered worthwhile to study in detail the interactions between DNA and a ...
Gotor Candel, Raul Jesús; Costero Nieto, Ana María; Gil Grau, Salvador; Parra Álvarez, Margarita; Martínez Mañez, Ramón; Sancenón Galarza, Félix; Gaviña Costero, Pablo(Royal Society of Chemistry, 2013-06-25)
Two triphenylmethane based chemodosimeters for selective and chromogenic sensing of cyanide anions in aqueous environments and of hydrogen cyanide in gas phase were prepared and studied.
Nardi, Giacomo; Lineros-Rosa, Mauricio; Palumbo, Fabrizio; Miranda Alonso, Miguel Ángel; Lhiaubet, Virginie Lyria(Elsevier, 2021-01-15)
[EN] Dipicolinic acid (DPA), present in large amount in bacterial spores, has been proposed to act as an endogenous photosensitizer in spore photoproduct formation. The proposed mechanism involves a triplet-triplet energy ...
Photoinduced intramolecular electron transfer in linked systems, (R,S)-
and (S,S)-naproxen-N-methylpyrrolidine dyads, has been studied by means of spin
chemistry methods [magnetic field effect and chemically induced ...
Aparici-Espert, Maria Isabel; Miranda Alonso, Miguel Ángel; Lhiaubet, Virginie Lyria(MDPI AG, 2018-03)
[EN] Photosensitization by drugs is a problem of increasing importance in modern life. This phenomenon occurs when a chemical substance in the skin is exposed to sunlight. Photosensitizing drugs are reported to cause severe ...
Vendrell Criado, Victoria; Rodríguez Muñiz, Gemma María; Lhiaubet ., Virginie Lyria; Cuquerella Alabort, Maria Consuelo; Miranda Alonso, Miguel Ángel(John Wiley & Sons, 2016)
[EN] Based on our previous investigations into the photophysical properties of the 5-methyl-2-pyrimidone (Pyo) chromophore, we now extend our studies to the photobehavior of the dimeric (6-4) thymine photoproducts (6-4 PP) ...
Navarrete-Miguel, Miriam; Francés-Monerris, Antonio; Miranda Alonso, Miguel Ángel; Lhiaubet, Virginie Lyria; Roca-Sanjuan, Daniel(MDPI AG, 2021-05)
[EN] Photocycloreversion plays a central role in the study of the repair of DNA lesions, reverting them into the original pyrimidine nucleobases. Particularly, among the proposed mechanisms for the repair of DNA (6-4) ...