Elena Fito, Santiago Fco; Lalic, Jasna(Wiley, 2013-12)
[EN] Forecasting plant virus emergence depends on identifying the factors that determine the distribution of genetic variants within the primary host as well as across potential new hosts. It is crucial to determine: (i) ...
González, Rubén; Butkovic, Anamarija; Escaray, Francisco J.; Martínez-Latorre, Javier; Melero, Izan; Pérez-Parets, Enric; Gómez-Cadenas, Aurelio; Carrasco, Pedro; Elena, Santiago F.(Proceedings of the National Academy of Sciences, 2021-02-09)
[EN] Environmental conditions are an important factor driving pathogens' evolution. Here, we explore the effects of drought stress in plant virus evolution. We evolved turnip mosaic potyvirus in well-watered and drought ...
Willemsen, Anouk; Zwart, Mark Peter; Higueras, Pablo; Sardanyes Cayuela, Jose; Elena Fito, Santiago Fco(Oxford University Press (OUP), 2016-09)
One of the striking features of many eukaryotes is the apparent amount of redundancy in coding and non-coding elements of their genomes. Despite the possible evolutionary advantages, there are fewer examples of redundant ...
González, Rubén; Butkovic, Anamarija; ELENA FITO, SANTIAGO FCO(Oxford University Press, 2019-07)
[EN] Predicting viral emergence is difficult due to the stochastic nature of the underlying processes and the many factors that govern pathogen evolution. Environmental factors affecting the host, the pathogen and the ...
Tromas, Nicolas; Zwart, Mark Peter; Forment Millet, José Javier; Elena Fito, Santiago Fco(Oxford University Press, 2014)
[EN] Nonretroviral integrated RNA viruses (NIRVs) are genes of nonretroviral RNA viruses found in the genomes of many eukaryotic organisms. NIRVs are thought to sometimes confer virus resistance, meaning that they could ...
Minicka, J; Elena Fito, Santiago F.; Borodynko-Filas, N.; Rubis, B.; Hasiów-Jaroszewska, B.(Springer (Biomed Central Ltd.), 2017)
[EN] Pepino mosaic virus (PepMV) is an emerging plant pathogen that infects tomatoes worldwide.
Understanding the factors that influence its evolutionary success is essential for developing new control strategies that
may ...
Hillung, Julia; Cuevas Torrijos, Jose Manuel; Elena Fito, Santiago Fco(Frontiers Media, 2012-06)
The use of high-throughput transcript profiling techniques has opened the possibility of
identifying, in a single experiment, multiple host mRNAs whose levels of accumulation are
altered in response to virus infection. ...
Hasiow-Jaroszewska, B; Czerwoniec, A; Pospieszny, H; Elena Fito, Santiago Fco(BioMed Central, 2011-06-24)
[EN] Background: Pepino mosaic virus (PepMV) is considered one of the most dangerous pathogens infecting tomatoes worldwide. The virus is highly diverse and four distinct genotypes, as well as inter-strain recombinants, ...
Martinez Garcia, Fernando; Lafforgue, Guillaume; Morelli, M.; González-Candelas, F.; CHUA, N.H.; Daros Arnau, Jose Antonio; Elena Fito, Santiago Fco(Oxford University Press (OUP), 2012-11)
[EN] Plant artificial micro-RNAs (amiRs) have been engineered to target viral genomes and induce their degradation. However, the exceptional evolutionary plasticity of RNA viruses threatens the durability of the resistance ...
Cervera-Benet, Héctor; Ambros Palaguerri, Silvia; Bernet, Guillermo P.; Rodrigo Tarrega, Guillermo; Elena Fito, Santiago Fco(Oxford University Press, 2018-07)
[EN] Determining the fitness of viral genotypes has become a standard practice in virology as it is essential to evaluate their evolutionary potential. Darwinian fitness, defined as the advantage of a given genotype with ...