Ballester Beltrán, José(Universitat Politècnica de València, 2011-11-11)
Se ha demostrado ampliamente que la adsorción de proteínas y la adhesión celular dependen de las características físico-químicas de los materiales. Sin embargo, pocas veces se ha estudiado la respuesta celular en materiales ...
[EN] Definitive hematopoietic stem cells (HSCs) derive from specialized regions of the endothelium known as the hemogenic endothelium (HE) during embryonic developmental processes. This knowledge opens up new possibilities ...
Genetically modified Lactococcus lactis, non-pathogenic bacteria expressing the FNIII7-10 fibronectin
fragment as a protein membrane have been used to create a living biointerface between synthetic materials
and mammalian ...
Costa Martínez, Elisa; González García, Cristina; Gómez Ribelles, José Luís; Salmerón Sánchez, Manuel(SAGE Publications, 2018-08-06)
[EN] Articular chondrocytes are difficult to grow, as they lose their characteristic phenotype following expansion on standard tissue culture plates. Here, we show that culturing them on surfaces of poly(L-lactic acid) of ...
Llopis Hernández, Virginia(Universitat Politècnica de València, 2017-11-03)
This thesis ventures with the extracellular matrix protein (ECM) fibronectin (FN) as an interface protein in the interaction between cells and materials to design microenvironment for future use in tissue engineering. It ...
García Cruz, Dunia Mercedes(Universitat Politècnica de València, 2009-04-02)
La ingeniería tisular es una ciencia que aplica los principios de la ingeniería y las ciencias de la vida para desarrollar sustitutos biológicos que reparen o mejoren la función biológica de un tejido u órgano (según la ...
Anisotropy is one of the most meaningful determinants of biomechanical behaviour. This study employs micro-computed tomography (mu CT) and image techniques for analysing the anisotropy of regenerative medicine polymer ...
Sabater i Serra, Roser; Kyritsis, A.; Escobar Ivirico, J.L.; Gómez Ribelles, José Luís; Pissis, P.; Salmerón Sánchez, Manuel(SPRINGER, 2011)
[EN] Poly( ε -caprolactone)/poly(hydroxyethyl acrylate) networks have been investigated by thermally stimulated depolarization currents (TSDC) and differential scanning calorimetry (DSC). The introduction of hydrophilic ...
Cardona Marsal, Ramón; Salmerón Sánchez, Manuel; Vallés Lluch, Ana; Moratal Pérez, David(Institute of Electrical and Electronics Engineers (IEEE), 2011-06)
This work presents the software implementation of a tissue engineering image analysis tool through the study of several biomaterials by means of different microscopy techniques (optical, scanning electron, and atomic force ...
[EN] Adsorption phenomena are characterized by models that include free parameters trying to reproduce experimental results. In order to understand the relationship between the model parameters and the material properties, ...
Salmerón Sánchez, Manuel; Molina Mateo, José; Romero Colomer, Francisco Jose; Gómez Ribelles, José Luís(Elsevier, 2006-06)
[EN] According to our previous results the free radical copolymerization of ethyl acrylate and hydroxyethyl methacrylate gives rise to a system having chain composition and morphology different from that of the random ...
Cantini, Marco; Sousa, Maria; Moratal Pérez, David; Mano, Joao F.; Salmerón Sánchez, Manuel(Royal Society of Chemistry, 2013-02)
[EN] In this study, we propose a methodology to obtain a family of biomimetic substrates with a hierarchical rough topography at the micro and nanoscale that span the entire range of wettability, from the superhydrophobic ...
Morata Martínez, Miranda(Universitat Politècnica de València, 2018-09-18)
[EN] The cellular response to biomaterials is mediated not only by the innate material properties but also
by different parameters of the interface protein layer on the surface of materials, such as their
conformation ...
[EN] The wettability of PLLA substrates was modified by plasma copolymerising on its surface thin films based on EA and HEA. The composition of the reactive gas inside the plasma chamber was that of the corresponding liquid ...
Currently, cell culture systems that include nanoscale topography are widely used in order to provide cells additional cues closer to the in vivo environment, seeking to mimic the natural extracellular matrix. Electrospinning ...
Poly(ethyl acrylate) (PEA) induces the formation of biomimetic fibronectin (FN) (nano)networks uponsimple adsorption from solutions, a process referred to as material-driven FN fibrillogenesis. The ability ofPEA to organize ...
Mukhatyar, Vivek J.; Salmerón Sánchez, Manuel; Rudra, Soumon; Mukhopadaya, Shoumit; Barker, Thomas H.; Garcia, Andres J.; Bellamkonda, Ravi V.(Elsevier, 2011)
Bridging of long peripheral nerve gaps remains a significant clinical challenge. Electrospun nanofibers have been used to direct and enhance neurite extension in vitro and in vivo. While it is well established that oriented ...
Mnatsakanyan Movsesyan, Hayk(Universitat Politècnica de València, 2019-07-03)
[ES] Los procesos de comunicación celular permiten a las células desarrollar una acción coordinada durante la embriogénesis y asimilar de forma coherente las señales recibidas a través del entorno. Algunas de las moléculas ...