[EN] Senescent cells accumulate in multiple aging-associated diseases, and eliminating these cells has recently emerged as a promising therapeutic approach. Here, we take advantage of the high lysosomal beta-galactosidase ...
[EN] Here, a new bio-inspired nanoarchitectonics approach for the design of optical probes is presented. It is based on nanodevices that combine 1) an enzymatic receptor subunit, 2) a signaling subunit (consisting of a ...
Pascual, Lluís; Gras Romero, María Luisa; Vidal Brotons, Daniel José; Alcañiz Fillol, Miguel; Martínez-Máñez, Ramón; Ros-Lis, José Vicente(Elsevier, 2018)
[EN] The relevance of plant-based food alternatives to dairy products, such as vegetable milks, has been growing in recent decades, and the development of systems capable of classifying and predicting the sensorial profile ...
Campos Sánchez, Inmaculada; Alcañiz Fillol, Miguel; Aguado García, Daniel; Barat Baviera, Ramón; FERRER, J.; Gil Sánchez, Luís; Marrakchi, Mouna; Martínez Mañez, Ramón; Soto Camino, Juan; Vivancos Bono, José Luís(Elsevier, 2012-05-15)
The use of a voltammetric electronic tongue as tool for the prediction of concentration levels of certain water quality parameters from influent and effluent wastewater from a Submerged Anaerobic Membrane Bioreactor pilot ...
[EN] The use of a voltammetric electronic tongue for the quantitative analysis of quality parameters in influent wastewater from a wastewater treatment plant (WWTP) that treats domestic and industrial wastewater is proposed. ...
A humid electronic nose device based on pulse voltammetry has been applied to detect nerve agentsimulants in gas phase. The humid electronic nose consists in a polypropylene piece which containsan array of eight metallic ...
Godoy-Reyes, Tania Mariel; Llopis-Lorente, Antoni; García-Fernández, Alba; Gaviña, Pablo; Costero, Ana M.; Martínez-Máñez, Ramón; Sancenón Galarza, Félix(The Royal Society of Chemistry, 2019)
[EN] Mesoporous silica nanoparticles capped with acetylcholinesterase, through boronic ester linkages, selectively release an entrapped cargo in the presence of acetylcholine.
Pascual, Lluís; El Sayed Shehata Nasr, Sameh; Marcos Martínez, María Dolores; Martínez-Máñez, Ramón; Sancenón Galarza, Félix(John Wiley & Sons, 2017)
[EN] Two different acetylcholinesterase (AChE)-capped mesoporous silica nanoparticles (MSNs), S1-AChE and S2-AChE, were prepared and characterized. MSNs were loaded with rhodamine B and the external surface was functionalized ...
Pascual, Lluís; El Sayed Shehata Nasr, Sameh; Martínez-Máñez, Ramón; Costero Nieto, Ana María; Gil Grau, Salvador; Gaviña Costero, Pablo; Sancenón Galarza, Félix(American Chemical Society, 2016-11-04)
Mesoporous silica nanoparticles loaded with rhodamine B and capped with acetylcholinesterase are able to be selectively opened and deliver their cargo in the presence of nerve agent simulant diisopropyl fluorophosphate (DFP).
Candel Busquets, Inmaculada; Aznar Gimeno, Elena; Mondragón Martínez, Laura; De la Torre Paredes, Cristina; Martínez Mañez, Ramón; Sancenón Galarza, Félix; Marcos Martínez, María Dolores; Amoros del Toro, Pedro Jose; Guillem, Carmen; Pérez Payá, Enrique; Costero Nieto, Ana María; Gil Grau, Salvador; Parra Álvarez, Margarita(Royal Society of Chemistry, 2012-10-02)
MCM-41 silica nanoparticles were used as inorganic scaffolding to prepare a nanoscopic-capped hybrid material S1, which was able to release an entrapped cargo in the presence of certain enzymes, whereas in the absence of ...
Ammonia (NH4 N) and orthophosphate (PO4
P) quantification in wastewater treatment plants is important
due to their implication in the eutrophication process.
A voltammetric electronic tongue as a tool for the
prediction ...
Oroval Cucarella, María del Mar; Climent Terol, Estela; Coll Merino, Mª Carmen; Eritja, Ramon; Aviñó, Anna; Marcos Martínez, María Dolores; Sancenón Galarza, Félix; Martínez Mañez, Ramón; Amoros del Toro, Pedro Jose(Royal Society of Chemistry, 2013-06-18)
An aptamer-capped mesoporous material for the selective and sensitive detection of &-thrombin in human plasma and serum has been prepared and characterised.
An electronic nose system (E-nose) with metal oxide semiconductor sensors (MOS) has been designed
to discriminate and quantify different chemical warfare agents (CWA) mimics. The E-nose consists of an
array of commercial ...
An electronic tongue has been developed to monitor the presence of ammonium nitrate in water. It is based on pulse voltammetry and consists of an array of eight working electrodes (Au; Pt; Rh; Ir; Cu; Co; Ag and Ni) ...
Pérez-Calabuig, Ana M.; Diez-Sánchez, Paula; Martínez-Ruiz, Paloma; Martínez-Máñez, Ramón; Sánchez, Alfredo; Villalonga, Reynaldo(The Royal Society of Chemistry, 2020-06-14)
[EN] A novel nanomachine for dual and sequential delivery of two different compounds was developed by grafting a thiol group and a pH sensitive beta-cyclodextrin-based gate-like ensemble on acetylcholinesterase-modified ...
EL SAYED SHIHATA NASR, SAMEH; Agostini, Alessandro; Santos Figueroa, Luis E.; Martínez Mañez, Ramón; Sancenón Galarza, Félix(Wiley Open Access, 2013-04-03)
The fast and the fluoride: A pyridine derivative functionalized with tert-butyldimethylsilyl ether has been synthesized and used as a selective chromofluorogenic fluoride sensor in water/cetyltrimethylammonium bromide ...
[EN] The construction of communication models at the micro¿/nanoscale involving abiotic nanodevices and living organisms has the potential to open a wide range of applications in biomedical and communication technologies. ...
Lozano-Torres, Beatriz; Galiana, Irene; Rovira, M.; Garrido-García, Eva María; Chaib, Selim; Bernardos Bau, Andrea; Muñoz-Espín, Daniel; Serrano, M.; Martínez-Máñez, Ramón; Sancenón Galarza, Félix(American Chemical Society, 2017)
[EN] A naphthalimide-based two-photon probe (AHGa) for the detection of cell senescence is designed. The probe contains a naphthalimide core, an L-histidine methyl ester linker, and an acetylated galactose bonded to one ...
Moragues Pons, María Esperanza; Montes Robles, Roberto; Ros-Lis, José Vicente; Alcañiz Fillol, Miguel; Ibáñez Civera, Francisco Javier; Pardo Vicente, María Teresa; Martínez Mañez, Ramón(Elsevier, 2014-02)
The design, fabrication and validation of an optoelectronic sensor implemented in an easy-to-use portable device for the selective and sensitive detection of CO in air is reported herein. The system is based on the colour ...
Rodríguez García, Miguel Ramón(Universitat Politècnica de València, 2022-09-05)
[ES] Este proyecto se basa en el análisis del movimiento de nanomotores mediante técnicas de
microscopía. Los nanomotores, también conocidos como nanorobots, son sistemas basados en
micro/nanopartículas capaces de ...