[EN] The recent demand for fluorescent-labeled materials (FLMs) in forensic security concepts such as latent fingerprints (LFs) that encode information for anti-counterfeiting and encryption of confidential data makes ...
Limones Herrero, Daniel(Universitat Politècnica de València, 2016-01-07)
[EN] The use of biomimetic media such as serum albumins (SAs), a1-acid glycloproteins (AAGs), cyclodextrins (CDs) and sodium dodecyl sulfate (SDS) micelles is combined with photophysical techniques (fluorescence (F) and ...
Pérez Ruiz, Raul; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel(American Chemical Society, 2014-04)
[EN] Discovered more than eight decades ago, the Diels-Alder (DA) cycloaddition (CA) remains one of the most versatile tools in synthetic organic chemistry. Hetero-DA processes are powerful methods for the synthesis of ...
[EN] The largely demand in continued security issues makes necessary the development of novel materials with outstanding properties to improve the current detection techniques. In this context, latent fingerprint (LF) by ...
Herrera-Luna, Jorge Carlos; Díaz Díaz, David; Jiménez Molero, María Consuelo; Pérez-Ruiz, Raúl(American Chemical Society, 2021-10-07)
[EN] A new strategy to achieve efficient aerobic phosphorylation of five-membered heteraroenes with excellent yields using dichromatic photoredox catalysis in a gel-based nanoreactor is described here. The procedure involves ...
Molins-Molina, Oscar; Lence, Emilio; Limones-Herrero, Daniel; González-Bello, Concepción; Miranda Alonso, Miguel Ángel; Jiménez Molero, María Consuelo(Royal Society of Chemistry, 2019-01-07)
[EN] The non-steroidal anti-inflammatory drug (S)-carprofen (CPF) has been used as a photoactive probe to investigate the possible existence of a common recognition center in serum albumins (SAs) of different species. The ...
Vayá Pérez, Ignacio; Gustavsson, Thomas; Markovitsi, Dimitra; Miranda Alonso, Miguel Ángel; Jiménez Molero, María Consuelo(Elsevier, 2016-05-15)
[EN] The photoreactivity of diastereomeric dyads containing (S)- or (R)-flurbiprofen (FBP) and (S)-Tyr, either directly linked (1) or separated by a cyclic spacer (3) has been investigated. The main feature is a remarkable ...
Bueno Alejo, Carlos Javier(Universitat Politècnica de València, 2009-12-04)
Recientemente se ha usado la técnica de fotólisis de destello láser para el estudio de las interacciones fármaco/proteína, demostrando que el estado excitado triplete es muy sensible al medio que le rodea y que, por tanto, ...
Bonancía Roca, Paula; Vayá Pérez, Ignacio; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel(American Chemical Society, 2012-12-27)
The two enantiomers of 2-(2-hydroxybiphenyl-4-yl)propanoic acid ((S)- and (R)-BPOH) have been selected as probes for human serum albumin (HSA). Photophysical characterization in the absence of protein led to emission maxima, ...
Limones Herrero, Daniel; Palumbo, Fabrizio; Vendrell Criado, Victoria; Andreu Ros, María Inmaculada; Lence, Emilio; González-Bello, Concepción; Miranda Alonso, Miguel Ángel; Jiménez Molero, María Consuelo(Elsevier, 2020-02-05)
[EN] Transient absorption spectroscopy in combination with in silico methods has been employed to study the interactions between human serum albumin (HSA) and the anti-psychotic agent chlorpromazine (CPZ) as well as its ...
Echavarren Pardo, Leire(Universitat Politècnica de València, 2022-07-26)
[ES] Se trata de construir y desarrollar una nueva batería hecha a partir de un cátodo de hierro, no de litio que es el material más usado para este propósito, y que funcione al mismo rendimiento que las baterías de este ...
Manjavacas, Alejandro; Fenollosa Esteve, Roberto; Rodriguez, Isabelle; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel; Meseguer Rico, Francisco Javier(The Royal Society of Chemistry, 2017)
[EN] Most optical processes occurring in nature are based on the well-known selection rules for opticaltransitions between electronic levels of atoms, molecules, and solids. Since in most situations themagnetic component ...
Limones-Herrero, Daniel; Pérez Ruiz, Raul; Lence, Emilio; Gonzalez-Bello, Concepcion; Miranda Alonso, Miguel Ángel; Jiménez Molero, María Consuelo(The Royal Society of Chemistry, 2017-04-01)
[EN] A multidisciplinary strategy to obtain structural information on the intraprotein region is described here. As probe ligands, (S)- and (R)-CPFMe (the methyl esters of the chiral drug carprofen) have been selected, ...
Vayá Pérez, Ignacio; Andreu Ros, María Inmaculada; Monje-López, Vicente Tomás; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel(American Chemical Society, 2016-01)
[EN] The photoreactivity of fenofibric acid (FA) in the presence of human and bovine serum albumins (HSA and BSA, respectively) has been investigated by steady-state irradiation, fluorescence, and laser flash photolysis ...
Pérez Ruiz, Raúl; Alonso Ruiz, Rafael; Nuin Plá, Neus Edurne; Andreu Ros, María Inmaculada; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel(American Chemical Society, 2011-04-21)
[EN] Three drugs containing the naphthalene (NP) chromophore, namely, naproxen (NPX), propranolol (PPN), and cinacalcet (CIN), but with different affinities toward serum albumins (SAs) and alpha-1-acid glycoproteins (AAGs) ...
Pérez Ruiz, Raul; Sáez Cases, José Antonio; Domingo, Luis R.; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel(American Chemical Society, 2012)
Oxidative electron transfer cycloreversion of trans,trans-2-cyclopropyl-4-methyl-3-phenyloxetane, using triphenylthiapyrylium perchlorate as a photosensitizer, leads to distonic 1,4-radical cations; subsequent cleavage ...
García -Laínez, Guillermo; Ana M Marínez-Reig; Limones Herrero, Daniel; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel; Andreu Ros, María Inmaculada(Elsevier, 2018)
[EN] Diclofenac (DCF) can cause adverse reactions such as gastrointestinal, renal and cardiovascular disorders;
therefore, topical administration may be an attractive alternative to the management of local pain in order ...
Vayá Pérez, Ignacio; Lhiaubet-Vallet, Virginie Lyria; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel(Royal Society of Chemistry, 2014-03-18)
[EN] The properties of singlet and triplet excited states are strongly medium-dependent.
Hence, these species constitute valuable tools as reporters to probe compartmentalised
microenvironments, including drug@protein ...
Vendrell-Criado, Victoria; Angulo-Pachón, César A.; Miravet, Juan F.; Galindo, Francisco; Miranda Alonso, Miguel Ángel; Jiménez Molero, María Consuelo(Elsevier, 2020-01)
[EN] In this work, a molecular hydrogel made of gelator (S)-4-((3-methyl-1-(nonylamino)-1-oxobutan-2-yl)amino)-4-oxobutanoic acid (SVN) has been employed as soft container to modify the photochemical and photophysical ...
Molins-Molina, Oscar; Pérez Ruiz, Raúl; Lence, Emilio; González-Bello, Concepción; Miranda Alonso, Miguel Ángel; Jiménez Molero, María Consuelo(Frontiers Media SA, 2019-09-20)
[EN] Triflusal is a platelet antiaggregant employed for the treatment and prevention of thromboembolic diseases. After administration, it is biotransformed into its active metabolite, the 2-hydroxy-4-trifluoromethylbenzoic ...