Lozano-Torres, Beatriz; Galiana, Irene; Rovira, M.; Garrido-García, Eva María; Chaib, Selim; Bernardos Bau, Andrea; Muñoz-Espín, Daniel; Serrano, M.; Martínez-Máñez, Ramón; Sancenón Galarza, Félix(American Chemical Society, 2017)
[EN] A naphthalimide-based two-photon probe (AHGa) for the detection of cell senescence is designed. The probe contains a naphthalimide core, an L-histidine methyl ester linker, and an acetylated galactose bonded to one ...
Lozano-Torres, Beatriz; Marcos Martínez, María Dolores; Pardo Vicente, María Teresa; Sancenón Galarza, Félix; Martínez-Máñez, Ramón; Rurack, K.(Taylor & Francis, 2018)
[EN] Probe 1, which contains an anilinopyridine chromophore and an aza-oxa macrocyclic subunit, presented an absorption band centered at 340 nm in acetonitrile. Addition of Fe(III), Cr(III) and Hg(II) induced the growth ...
Three different mesoporous silica nano-sized materials (SC1, SC2, and SC3), loaded with [Ru(bipy)(3)](2+) dye (bipy= bipyridine) and functionalized on the external surface with three macrocyclic copper(II) complexes (C1, ...
Climent Terol, Estela; Martínez Mañez, Ramón; Maquieira Catala, Ángel; Sancenón Galarza, Félix; Marcos Martínez, María Dolores; Brun Sánchez, Eva María; Soto Camino, Juan; Amoros del Toro, Pedro(Wiley Open Access, 2012)
[EN] The synthesis of capped mesoporous silica nanoparticles (MSN)
conjugated with an antibody (AB) as a gatekeeper has been
carried out in order to obtain a delivery system able to release
an entrapped cargo (dye) in ...
Polo, Lorena; Díaz de Greñu-Puertas, Borja; Della Bella, Elena; Pagani, Stefania; Torricelli, Paola; Vivancos, José-Luis; Ruiz Rico, María; Barat Baviera, José Manuel; Aznar, Elena; Martínez-Máñez, Ramón; Fini, Milena; Sancenón Galarza, Félix(Elsevier, 2018-11)
[EN] Infections represent one of the most frequent causes of arthroplasty revision. Thus, design of new antimi-crobial scaffolds to reduce implant rejections, bone infections and associated medical costs is highlydesired. ...
Pla, Luis; Santiago Felipe, Sara; Tormo-Mas, María Ángeles; Pemán, Javier; Sancenón Galarza, Félix; Aznar, Elena; Martínez-Máñez, Ramón(Elsevier, 2020-10-01)
[EN] The development of new detection systems for an accurate and rapid identification of pathogens has become an essential challenge in the biomedical field. Herein a highly selective platform based on aptamer-gated nano ...
Royo Calvo, Santiago; Gotor Candel, Raul Jesús; Costero Nieto, Ana María; Parra Álvarez, Margarita; Gil Grau, Salvador; Martínez Mañez, Ramón; Sancenón Galarza, Félix(Royal Society of Chemistry, 2012-04-13)
Two new aryl carbinols (1 and 3) have been synthesised and characterised and their ability as OFF-ON probes for the chromogenic detection of the nerve agent simulant in acetonitrile has been tested. In addition compound 2 ...
Llopis-Lorente, Antoni; de Luis-Fernández, Beatriz; García-Fernández, Alba; Diez, Paula; Sánchez, Alfredo; Marcos Martínez, María Dolores; Villalonga, Reynaldo; Martínez-Máñez, Ramón; Sancenón Galarza, Félix(The Royal Society of Chemistry, 2017)
[EN] We report a delivery system based on Au-mesoporous silica (MS) nanoparticles functionalized with acetylcholinesterase on the Au face as a control unit and with disulfide-containing oligo(ethylene glycol) chains on the ...
Dos Santos, S.N.; Rezende Dos Reis, S.R.; Pires, L.P; Helal-Neto, E.; Sancenón Galarza, Félix; Barja-Fidalgo, T.C.; Medina De Mattos, R.; Nasciutti, L.E.; Martínez-Máñez, Ramón; Santos-Oliveira, R.(Elsevier, 2017)
[EN] The mononuclear phagocytic system is a key participant determining the half-life of nanoparticles (NPs) in the bloodstream and influencing active targeting. Several strategies to extend the circulation time of ...
El Sayed Shehata Nasr, Sameh; De la Torre Paredes, Cristina; Santos Figueroa, Luis Enrique; Marín Hernández, Cristina; Martínez Mañez, Ramón; Sancenón Galarza, Félix; Costero Nieto, Ana María; Gil, Salvador; Parra, Margarita(Elsevier, 2015-02)
[EN] Three fluorescent probes (1–3) for the selective and sensitive detection of hydrogen sulfide have been synthesized and characterized. Probe 1 is a coumarin derivative functionalized with an azide moiety whereas 2 ...
Finding fluoride: An azo dye functionalized with tert-butyldimethylsilyl ether has been synthesized and used as a selective chromogenic fluoride sensor in the acetonitrile/water mixtures. The chromogenic response arises ...
Bernardos Bau, Andrea; Mondragón Martínez, Laura; Javakhishvili, Irakli; Mas Font, Nuria; De la Torre Paredes, Cristina; Martínez Mañez, Ramón; Sancenón Galarza, Félix; Barat Baviera, José Manuel; Hvilsted, Soren; Orzaez, Mar; Pérez Payá, Enrique; Amorós, Pedro(Wiley-VCH Verlag, 2012-10-08)
The synthesis and characterisation of new capped silica mesoporous nanoparticles for on-command delivery applications is reported. Functional capped hybrid systems consist of MCM-41 nanoparticles functionalised on the ...
[EN] We report herein an evaluation of the effect of several mesoporous silica nanoparticles (MSNs) on the cellular uptake and in vitro cytotoxicity in human cells. Bare MSNs and MSNs functionalized with polyethylene glycol ...
[EN] Biocompatible ZnS-based nanocrystals capped with 4-mercaptophenylboronic acid (ZnS@B) have been size-designed as excellent pH responsive gatekeepers on mesoporous silica nanoparticles (MSNs), which encapsulate fluorophore ...
Juárez, L.A.; Costero, Ana M.; Parra, Margarita; Gil, Salvador; Ródenas, J.; Sancenón Galarza, Félix; Martínez-Máñez, Ramón(The Royal Society of Chemistry, 2016)
[EN] Four probes based in the use of a biphenyl moiety and functionalized with trimethylsilyl benzyl ether (P1 and P3) and oxime (P2 and P4) groups have been prepared and tested as optical probes for the detection of NO2. ...
[EN] The development of easy and affordable methods for the detection of cyanide is of great significance due to the high toxicity of this anion and the potential risks associated with its pollution. Herein, optical detection ...
[EN] Excessive apoptotic cell death is at the origin of several pathologies, such as degenerative disorders, stroke or ischemia-reperfusion damage. In this context, strategies to improve inhibition of apoptosis and other ...
de la torre, Cristina; Mondragón Martínez, Laura; Coll Merino, Mª Carmen; Sancenón Galarza, Félix; Marcos Martínez, María Dolores; Martínez Mañez, Ramón; Amoros del Toro, Pedro Jose; Pérez Payá, Enrique; Orzáez Calatayud, Mar(Wiley-VCH Verlag, 2014-11-17)
New capped silica mesoporous nanoparticles for intracellular controlled cargo release within cathepsin B expressing cells are described. Nanometric mesoporous MCM-41 supports loaded with safranin O (S1-P) or doxorubicin ...
Sanfeliu Cano, Cristina; Martínez-Máñez, Ramón; Sancenón Galarza, Félix; Soto Camino, Juan; Amoros del Toro, Pedro Jose; Marcos Martínez, María Dolores(Elsevier, 2015-10-15)
Due to the narrowrange between boron necessities and toxicity in the environment, there is a high interest in the design of effective boron remediation procedures. We have previously reported a promising boron adsorptionmaterial ...
Barba Bon, Andrea; Costero Nieto, Ana María; Gil Grau, Salvador; Sancenón Galarza, Félix; Martínez Mañez, Ramón(Royal Society of Chemistry, 2014-11-11)
Two new Eu3+ and Au3+ BODIPY-complexes capable of chromofluorogenically
detecting micromolar concentrations of V-type
nerve agent surrogates by a simple displacement assay are described