Guillen Guille, Isabel; Martínez SanMartín, Ángel; Gabaldón Hernández, José Antonio; Núñez Delicado, Estrella; Puchades Pla, Rosa; Maquieira Catala, Ángel(Ştefan cel Mare University – Suceava, 2011)
[EN] A lateral flow immunoassay (LFIA) was developed in the competitive reaction format and applied to test residues of the antimicrobial oxyteracycline (OTC) in honey samples. To prepare the assay test, a nitrocellulose ...
Selective covalent immobilization of thiolated oligonucleotides onto an epoxy-functionalized silicon-substrate can be achieved via light radiation (365 nm). Following this approach, thiol-modified oligonucleotide probes ...
[EN] A novel label-free biosensing approach based on bioreceptor networks patterned as diffractive gratings (biogratings) has been developed. Nanogrooved structures were used as optically active scaffolds for producing ...
Tortajada-Genaro, Luis Antonio; Niñoles Rodenes, Regina; Mena-Mollá, Salvador; Maquieira Catala, Angel(The Royal Society of Chemistry, 2019)
[EN] The development of a high-performance assay readout using integrated detectors is a current challenge in the implementation of DNA tests in diagnostic laboratories, particularly for supporting pharmacogenetic tests. ...
Juárez-Rodríguez, María José; Morais, Sergi; Maquieira Catala, Angel(Elsevier, 2021-02-01)
[EN] Microanalytical systems have huge potential for prognosis and diagnosis of diseases where the quantification of biomarkers is the critical factor. Immunoglobulin E (IgE)-associated allergy is the most common immune ...
DNA binding chemistry on silicon surface has been investigated. Aminated oligonucleotide probes were immobilized on the chip surface by chemical silanization and further covalent attachment. The chemistries employed were ...
[EN] A rapid strategy for the covalent immobilization of DNA onto silicon-based materials using the UV-initiated radical thiol-ene reaction is presented in this study. Following this approach, thiol- and alkene-modified ...
Direct hapten-linked multiplexed immunoassay is developed on the polycarbonate surface of standard Digital Versatile Discs (DVDs) for six compounds of environmental concern, as proof of concept. Carboxylated haptens are ...
[EN] The idea of using disk drives to monitor molecular biorecognition events on regular optical discs has received considerable attention during the last decade. CDs, DVDs, Blu-ray discs and other new optical discs are ...
Lázaro-Zaragozá, Ana; Maquieira Catala, Angel; Tortajada-Genaro, Luis Antonio(American Chemical Society, 2022-02-21)
[EN] Massive DNA testing requires novel technologies to support a sustainable health system. In recent years, DNA superstructures have emerged as alternative probes and transducers. We, herein, report a multiplexed and ...
Quintero Campos, Pedro(Universitat Politècnica de València, 2023-01-16)
[ES] El diagnóstico de alergias a antibióticos ß-lactámicos incluye el uso de pruebas in vivo no satisfactorias ya que consumen mucho tiempo y conllevan el riesgo de provocar una nueva reacción alérgica. Por otro lado, los ...
Sancho-Fornes, Gabriel; Avella-Oliver, Miquel; Carrascosa Rubio, Javier; Fernández-Sánchez, María Estrella; Brun, Eva M.; Maquieira Catala, Ángel(Elsevier, 2019)
[EN] One-dimensional photonic crystal slabs are periodic optical nanostructures that produce guided-mode resonance. They couple part of the incident light into the waveguide generating bandgaps in the transmittance spectrum, ...
Dispersive solid-phase extraction (dSPE) using fatty acid-coated Eu2O3 nanoparticles (NPs) was developed, and a direct immunoassay was carried out employing these NPs as support. Secondary antibodies labeled with fluorophore ...
Jornet Olivé, Maria Dolors(Editorial Universitat Politècnica de València, 2010-07-30)
La determinación y control de contaminantes orgánicos ha despertado gran interés en los últimos años. Estos compuestos se acumulan en los ecosistemas terrestres y acuáticos, cosa que los hace especialmente perjudiciales ...
[EN] Analyte-sensitive DNA-based hydrogels find multiple applications in the field of biosensors due to their adaptable nature. Here, the design of DNA-based hydrogel and its application as sensing platform for the detection ...
[EN] A highly sensitive hybridization assay is developed for detection of specific sequences of genomic DNAwithout thermal or isothermal chain reaction cycling. The assays in microarray format were performedon polymeric ...
Escorihuela Fuentes, Jorge; González Martínez, Miguel Ángel; López-Paz, José Luis; Puchades, Rosa; Maquieira Catala, Ángel; Giménez Romero, David(American Chemical Society, 2015-01-14)
[EN] The challenging lecture given in 1959 by physicist and Nobel Prize awarded R. P. Feynman:
“There's plenty of room at the bottom” is considered to be the starting point for
nanotechnology. With this peculiar title, ...
[EN] The quartz crystal microbalance (QCM) technique has been applied for monitoring the biorecognition of ArtinM lectins at low horseradish peroxidase glycoprotein (HRP) concentrations, using a simple kinetic model based ...
Endocrine disruptors (EDs) interfere with the development and functioning of the endocrine system, causing reproductive disturbance in aquatic wildlife. The aim of the present work was to determine the presence of EDs in ...