Sarrion-Perdigones, Alejandro; Vázquez Vilar, Marta; Palací Bataller, Jorge; Castelijns, Bas; Forment Millet, José Javier; Ziarsolo Areitioaurtena, Pello; Blanca Postigo, José Miguel; Granell Richart, Antonio; Orzáez Calatayud, Diego Vicente(American Society of Plant Biologists, 2013-07)
[EN] Plant synthetic biology aims to apply engineering principles to plant genetic design. One strategic requirement of plant synthetic biology is the adoption of common standardized technologies that facilitate the ...
Sarrión Perdigones, Manuel Alejandro; Juárez Ortega, Paloma; Fernández Del Carmen, María Asunción; Granell Richart, Antonio; Orzáez Calatayud, Diego Vicente(Public Library of Science, 2011)
Synthetic Biology requires efficient and versatile DNA assembly systems to facilitate the building of new genetic modules/pathways from basic DNA parts in a standardized way. Here we present GoldenBraid (GB), a standardized ...
Casas Rodrigo, Iván(Universitat Politècnica de València, 2017-09-06)
[ES] El reciente desarrollo y expansión de la Biología Sintética ha abierto un horizonte
de nuevas posibilidades tecnológicas mediante el diseño de organismos vivos con funciones
biológicas mejoradas o con nuevas funciones ...
Climent Catalá, Alicia(Universitat Politècnica de València, 2018-09-19)
[EN] Synthetic Biology is a novel interdisciplinary field that aims to re-design existing natural
biological systems or even to create new ones from an engineering perspective. Modularity,
standardization, abstraction, ...
Cocaliadis-Caisson, María Florencia; Fernandez-Munoz, Rafael; Pons Puig, Clara; Orzáez Calatayud, Diego Vicente; Granell Richart, Antonio(Oxford University Press (OUP), 2014-08)
[EN] Fruits are generally regarded as photosynthate sinks as they rely on energy provided by sugars transported from leaves to carry out the highly demanding processes of development and ripening; eventually these imported ...
[EN] Many synthetic biologists have adopted methods based on Type IIS restriction enzymes and Golden Gate technology in their cloning procedures, as these enable the combinatorial assembly of modular elements in a very ...
Pasin, Fabio; Bedoya, Leonor C.; Bernabé-Orts, Joan Miquel; Gallo, Araíz; Simón-Mateo, Carmen; Orzáez Calatayud, Diego Vicente; García, Juan Antonio(American Chemical Society, 2017-10)
[EN] Improved plants are necessary to meet human needs. Agrobacterium-mediated transformation is the most common method used to rewire plant capabilities. For plant gene delivery, DNA constructs are assembled into binary ...
Juárez Ortega, Paloma(Universitat Politècnica de València, 2011-11-28)
Edible fruits are inexpensive biofactories of recombinant molecules for oral intake, which can be
then delivered as crude extracts or partially purified formulations. Our group aims at the
production of human antibodies ...
[EN] Edible fruits are inexpensive biofactories for human health-promoting molecules that can be ingested as crude extracts or partially purified formulations. We show here the production of a model human antibody for ...
Rubio-Moraga, Angela; Rambla Nebot, Jose Luis; Fernández Del Carmen, María Asunción; Trapero Mozos, Almudena; Ahrazem, Oussama; Orzáez Calatayud, Diego Vicente; Granell Richart, Antonio; Gómez Gómez, Lourdes(Springer Verlag (Germany), 2014-11)
[EN] Apocarotenoid compounds play diverse communication functions in plants, some of them being as hormones, pigments and volatiles. Apocarotenoids are the result of enzymatic cleavage of carotenoids catalyzed by carotenoid ...
Huet Trujillo, Estefanía(Universitat Politècnica de València, 2017-11-06)
Genetic engineering has allowed the design and production of recombinant antibodies (rmAbs) in plants. Nowadays, rmAbs are used in the treatment of a wide range of pathologies such as infectious diseases, inflammatory ...
Valero Martínez, María Cristina(Universitat Politècnica de València, 2016-02-15)
[ES] Las plantas son consideradas un buen sistema para la expresión lo que permite usarlas como biofactorías. El uso de plantas como biofactorías tiene importantes ventajas en comparación con otras técnicas utilizadas, ...
Corbalán Acedo, Antonio(Universitat Politècnica de València, 2022-03-31)
[EN] Plant synthetic biology is a young and constantly growing field of science that
offers to society a wide variety of genetic tools to modify and to harness plant
metabolic complexity for human benefit. To date, several ...
Albaladejo Carrasco, Irene(Universitat Politècnica de València, 2014-02-04)
[ES] Los venenos contienen mezclas complejas de toxinas cuyo tratamiento efectivo requiere la administración de anticuerpos policlonales. En este trabajo se han producido colecciones de anticuerpos VHH fusionados a HSA y ...
Sacristán Tarrazó, Raquel(Universitat Politècnica de València, 2012-01-20)
Este proyecto se encuentra enmarcado en el campo del molecular farming, en el que las plantas se convierten en biofactorias de moléculas específicas, en este caso de mini-anticuerpos de llama (nanobodies o VHHs). Este ...
Juárez Ortega, Paloma(Universitat Politècnica de València, 2014-04-14)
Mucosal passive immunization is the transfer of active antibodies from one organism
to the mucosal surfaces of another organism for preventing or treating infectious diseases.
Mucosal passive immunization has a ...
[EN] To face the challenges of climate change and sustainable food production, it is essential to develop crop genome editing techniques to pinpoint key genes involved in abiotic stress signaling. The identification of ...
Fernández Del Carmen, María Asunción; Juárez Ortega, Paloma; Presa Castro, Silvia; Granell Richart, Antonio; Orzáez Calatayud, Diego Vicente(Elsevier, 2013-02-20)
The plant kingdom is an underexplored source of valuable proteins which, like plant lectins, display unique interacting specificities. Furthermore, plant protein diversity remains under-exploited due to the low availability ...
Ferrandis Martínez, Laura(Universitat Politècnica de València, 2014-09-19)
[ES] El desarrollo de las plantas es en su mayoría post-embrionario. Tras la
germinación, los nuevos órganos se originan en dos zonas localizadas en los polos opuestos de
la planta y que se denominan meristemos apicales, ...
Maioli, Alex; Gianoglio, Silvia; Moglia, Andrea; Acquadro, Alberto; Valentino, Danila; Milani, Anna Maria; Prohens Tomás, Jaime; Orzáez Calatayud, Diego Vicente; GRANELL RICHART, ANTONIO; Lanteri, Sergio; Comino, Cinzia(Frontiers Media SA, 2020-12-03)
[EN] Polyphenol oxidases (PPOs) catalyze the oxidization of polyphenols, which in turn causes the browning of the eggplant berry flesh after cutting. This has a negative impact on fruit quality for both industrial ...