Lucío, María Isabel; Hernández-Montoto, Andy; Fernández-Sánchez, María Estrella; Alamri, Sabri; Kunze, Tim; Bañuls Polo, María-José; Maquieira Catala, Ángel(Elsevier, 2021-12-01)
[EN] Responsive hydrogel-based surface relief gratings have demonstrated great performances as transducers in optical sensing. However, novel and smart designs of hydrogels are needed for the appropriate detection of ...
[EN] A label-free biosensor based on silicon-on-insulator (SOI) photonic bandgap (PBG) structures is performed for specific protein detection. First, the SOI sensing surface is functionalized using triethoxyvinylsilane ...
García García, Raquel(Universitat Politècnica de València, 2020-10-06)
[ES] La retinosis pigmentaria (RP) comprende un conjunto de enfermedades de origen genético que provocan la muerte progresiva de las células fotorreceptoras de la retina. Primero tiene lugar la muerte celular de los ...
[EN] A novel approach that may potentially be used to study biomolecular interactions including the simultaneous determination of structural and kinetic binding parameters is described in this Article for the first time. ...
[EN] Modulation of support wettability used for microarray format biosensing has led to an improvement of results. Hydrophobicity of glass chips was set by derivatizing with single vinyl organosilanes of different chain ...
Carbonell Ballesteros, Eduardo(Universitat Politècnica de València, 2022-07-08)
[ES] El reposicionamiento farmacéutico es una estrategia comercial muy común en la industria farmacéutica que consiste en el descubrimiento en fármacos ya aprobados de indicaciones alternativas a aquellas para las que estos ...
[EN] Despite the rising advances in the field of metal halide perovskite nanocrystals (NCs), the exploitation of such nanoparticles as luminescent labels for ex vivo imaging and biosensing is still unclear and in the early ...
[EN] Polyvinylidene fluoride (PVDF) membranes have become essential because of their huge applicability to the industry; however, they still present some limitations. This study focuses on the modification of PVDF membrane ...
[EN] We have recently demonstrated a biosensor based on a lattice of SU8 pillars on a 1 ¿m SiO 2/Si wafer by measuring vertically reflectivity as a function of wavelength. The biodetection has been proven with the combination ...
Stoks, Mara(Universitat Politècnica de València, 2022-07-08)
[ES] La Patología Digital está adquiriendo gran importancia al ser una alternativa robusta para el diagnóstico, estratificación, evaluación de tratamiento y estudio automatizado de distintos tipos de tumores sólidos. El ...
[EN] An approach is presented for covalent immobilization of biomolecules on an acrylate phosphorylcholine hydrogel. The immobilization and the hydrogel formation take place simultaneously by a thiol-acrylate coupling ...
[EN] In the literature, there are reports of the utilization of various hydrogels to create generic platforms for protein microarray applications. Here, a novel strategy was developed to obtain high-performance microarrays. ...
Peris Chanzá, Ernesto José; Bañuls Polo, María-José; Puchades, Rosa; Maquieira Catala, Ángel(Royal Society of Chemistry, 2013)
[EN] A methodology to modify Blu-ray disk (BD) surfaces by spin-coating an SU-8 epoxy photoresist is evaluated, to create a hybrid material with new functionalities. The optical performance of the new film surface disk is ...
[EN] This work addresses the main topics related to the photopolymerization process to develop and to monitor the analytical signal derived from biorecognition assays. We review basic aspects of photopolymerization, together ...
[EN] The storage of time-stable holographic gratings in hydrogel matrices when the material is immersed in aqueous media is a real challenge at present. The optimization of the storage stages of the holograms must be ...
Blanch García, Rebeca(Universitat Politècnica de València, 2016-10-17)
[ES] La proteína klotho es una β-glucuronidasa cuya sobrexpresión está relacionada con la prolongación de la vida. A pesar de que su mecanismo de acción todavía no se conoce con exactitud, estudios recientes sugieren ...
Vargas Valderrama, Alejandra(Universitat Politècnica de València, 2015-01-16)
[ES] Según la OMS (Organización Mundial de la Salud), cerca de 17 millones de personas murieron en 2008 debido a enfermedades cardiovasculares (CVD) convirtiéndose en un problema serio para la salud pública. Debido a esto, ...
[EN] A protocol for the covalent biofunctionalization of silicon-based biosensors using a UV light-induced thiol-ene coupling (TEC) reaction has been developed. This biofunctionalization approach has been used to immobilize ...
García Castelló, Javier; Toccafondo, Veronica; Escorihuela Fuentes, Jorge; Bañuls Polo, Mª José; Maquieira Catala, Ángel; García-Rupérez, Jaime(Optical Society of America, 2012)
[EN] In this letter, we present experimental results of antibody detection using a biosensor based on photonic bandgap structures, which are interrogated using a power-based readout technique. This interrogation method ...
[EN] We report a facile methodology to restore photoluminescence (PL) of CsPbBr3 nanocrystals (NCs) based on their postsynthetic modification with 3-aminopropyltriethoxysilane (APTES). By this methodology, a stark PL ...