Gregorio Collazo, Manuel(Universitat Politècnica de València, 2022-09-05)
[ES] El proceso de regeneración de tractos neurales formados por axones puede ser asistido mediante biomateriales (scaffolds) que sirvan de soporte de crecimiento y guía estructural. En el trabajo se realizará un estudio ...
Lecca Villacorta, Leandro(Universitat Politècnica de València, 2018-09-19)
[ES] Las lesiones del sistema nervioso provocan desórdenes neurológicos de naturaleza cognitiva, motora
y psíquica que afectan a millones de personas de todo el mundo. Las lesiones del sistema
nervioso periférico (SNP) ...
Glass transition and water dynamics in hydrated hyaluronic acid (HA) hydrogels crosslinked by divinyl sulfone (DVS) were studied by differential scanning calorimetry (DSC), dielectric relaxation spectroscopy (DRS) and water ...
Vallés Lluch, Ana; Arnal Pastor, María Pilar; Martínez-Ramos, Cristina; Vilariño, Guillermo; Vikingsson, Line; Monleón Pradas, Manuel(Institute of Electrical and Electronics Engineers, 2013)
[EN] Scaffolds of poly(ethyl acrylate) (PEA) with interconnected cylindrical orthogonal pores filled with a self-assembling peptide (SAP) gel are here proposed as patches for infarcted tissue regeneration. These combined ...
Baiget Orts, María Amparo(Universitat Politècnica de València, 2012-01-27)
The aim of this Thesis is to investigate the use of hyaluronic acid as a material for the design of scaffolds aimed at CNS regeneration. The motivation comes from the need of searching for new strategies that allow ...
Vallés Lluch, Ana; Poveda-Reyes, S.; Amoros del Toro, Pedro Jose; Beltran, D.; Monleón Pradas, Manuel(American Chemical Society, 2013-12)
Excessive water sorption and low mechanical properties are a severe drawback in some biomedical applications of hyaluronic acid (HA). A way to improve these properties is here explored through the novel concept of nanohybrid ...
[EN] Acrylic polymers have proved to be excellent with regard to cell adhesion, colonization and survival, in vitro and in vivo. Highly ordered and regular pore structures thereof can be produced with the help of polyamide ...
[EN] Myocardial tissue lacks the ability to regenerate itself significantly following a myocardial infarction. Thus, new strategies that could compensate this lack are of high interest. Cardiac tissue engineering (CTE) ...
Martinez-Diaz, Santos; Garcia-Giralt, Natalia; Lebourg, Myriam Madeleine; Gómez-Tejedor, José Antonio; Vila, Gemma; Caceres, Enric; Benito, Pere; Monleón Pradas, Manuel; Nogues, Xavier; Gómez Ribelles, José Luís; Monllau, Joan Carles(SAGE Publications (UK and US), 2010-03)
Background: Cartilage tissue engineering using synthetic scaffolds allows maintaining mechanical integrity and withstanding
stress loads in the body, as well as providing a temporary substrate to which transplanted cells ...
[EN] The interior of tissue engineering scaffolds must be vascularizable and allow adequate nutrients perfusion in order to ensure the viability of the cells colonizing them. The promotion of rapid vascularization of ...
[EN] Hydrogels have widely been proposed lately as strategies for neural tissue regeneration, but there are still some issues to be solved before their efficient use in tissue engineering of trauma, stroke or the idiopathic ...
[EN] Self-assembling peptides (SAP) are widely used as scaffolds themselves, and recently as fillers of microporous scaffolds, where the former provides a cell-friendly nanoenvironment and the latter improves its mechanical ...
Rodríguez Doblado, Laura(Universitat Politècnica de València, 2015-03-03)
[EN] Diseases of the central and peripheral nervous system have a large impact on the population
(consequences of stroke, neurodegenerative diseases as Parkinson disease, trauma, tumors)
and await new concepts for its ...
Vázquez Molina, Joan(Universitat Politècnica de València, 2017-06-19)
This PhD thesis is submitted as a \emph{compendium} of the articles \cite{NS, holographic, topological}. The following has been adapted from their abstracts.
Quantum mechanics has been argued to be a coarse--graining of ...
Valdes, Teresa; Rodríguez Jimenez, F. J.; García Cruz, Dunia Mercedes; Escobar Ivirico, Jorge Luis; Alastrue, Ana; Erceg, Slaven; Monleón Pradas, Manuel; Moreno-Manzano, Victoria(John Wiley & Sons, 2015-06)
[EN] Spinal cord injury (SCI) is a cause of paralysis. Although some strategies have been proposed to palliate the severity of this condition, so far no effective therapies have been found to reverse it. Recently, we have ...
[EN] Adsorption phenomena are characterized by models that include free parameters trying to reproduce experimental results. In order to understand the relationship between the model parameters and the material properties, ...
Martínez Ramos, Cristina; Gomez Pinedo, Ulises Alfonso; Garcia Esparza, Mª Ángeles; Soria Lopez, Jose Miguel; Barcia Albacar, Juan Antonio; Monleón Pradas, Manuel(Elsevier, 2015-06-26)
The objective of the present study was to evaluate the biocompatibility and cell hosting ability of a copolymer scaffold based on ethyl acrylate (EA) and hydroxyl ethyl acrylate (HEA) in vivo after an experimental brain ...
Araque Monrós, María Carmen; Gil-Santos, Luis; Monleón Pradas, Manuel; Más Estellés, Jorge(Taylor & Francis, 2020-10-02)
[EN] Objective: Although several different types of bioreactors are currently available with mechanical stimulation of constructs or prostheses for tendon regeneration, they are in many cases expensive and difficult to ...