[EN] The purpose of this project is to develop and validate a Deep Learning (DL) FDG PET imaging algorithm able to identify patients with any neurodegenerative diseases (Alzheimer's Disease (AD), Frontotemporal Degeneration ...
Coupé, Pierrick; Mansencal, Boris; Clement, Michael; Giraud, Rémi; Denis de Senneville, Baudouin; Ta, Vinh-Thong; Lepetit, Vincent; Manjón Herrera, José Vicente(Elsevier, 2020-10-01)
[EN] Whole brain segmentation of fine-grained structures using deep learning (DL) is a very challenging task since the number of anatomical labels is very high compared to the number of available training images. To address ...
Eskildsen, Simon F.; Coupé, Pierrick; Fonov, Vladimir; Manjón Herrera, José Vicente; Leung, Kelvin K.; Guizard, Nicolas; Wassef, Shafik N.; Østergaard, Lasse Riis; Collins, D. Louis; Alzheimer's Dis Neuroimaging(Elsevier, 2012-02-01)
Brain extraction is an important step in the analysis of brain images. The variability in brain morphology and the difference in intensity characteristics due to imaging sequences make the development of a general purpose ...
Carass, Aaron; Cuzzocreo, Jennifer L.; Han, Shuo; Hernandez-Castillo, Carlos R.; Rasser, Paul E.; Ganz, Melanie; Beliveau, Vincent; Dolz, Jose; Ben Ayed, Ismail; Desrosiers, Christian; Thyreau, Benjamin; Romero Gómez, José Enrique; Coupe, Pierrick; Manjón Herrera, José Vicente; Fonov, Vladimir(Elsevier, 2018-12)
[EN] The human cerebellum plays an essential role in motor control, is involved in cognitive function (i.e., attention, working memory, and language), and helps to regulate emotional responses. Quantitative in-vivo assessment ...
[EN] Brain imaging studies have shown that slow and progressive cerebral atrophy characterized the development of Alzheimer's Disease (AD). Despite a large number of studies dedicated to AD, key questions about the lifespan ...
Hett, Kilian; Ta, Vinh-Thong; Oguz, Ipek; Manjón Herrera, José Vicente; Coupé, Pierrick; Alzheimers Disease Neuroimaging Initiative(Elsevier, 2021-01)
[EN] The prediction of subjects with mild cognitive impairment (MCI) who will progress to Alzheimer¿s disease (AD) is clinically relevant, and may above all have a significant impact on accelerating the development of new ...
[EN] Numerous studies have proposed biomarkers based on magnetic resonance imaging (MRI) to detect and predict the risk of evolution toward Alzheimer's disease (AD). Most of these methods have focused on the hippocampus, ...
[EN] Previous literature about the structural characterization of the human cerebellum is
related to the context of a specific pathology or focused in a restricted age range. In
fact, studies about the cerebellum maturation ...
[EN] There is no consensus in literature about lifespan brain maturation and senescence, mainly because previous lifespan studies have been performed on restricted age periods and/or with a limited number of scans, making ...