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Browsing by Subject "Abietane"

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Browsing by Subject "Abietane"

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    Anti-Zika virus activity of several abietane-type ferruginol analogues 
    Sousa, Francielle T. G.; Nunes, Cristina; Malta Romano, Camila; Cerdeira Sabino, Ester; González-Cardenete, Miguel A (Universidade de São Paulo (USP), 2020)
    [EN] Abietane diterpenoids are naturally occurring plant metabolites with a broad spectrum of biological effects including antibacterial. antileishmanial, antitumor, antioxidant, as well as antiinfiammatory activities. ...
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    Antiviral Profiling of C-18-or C-19-Functionalized Semisynthetic Abietane Diterpenoids 
    González-Cardenete, Miguel A; Hamulic, Damir; Miquel-Leal, Francisco J.; González-Zapata, Natalia; Jimenez-Jarava, Orlando J.; Brand, Yaneth M.; Restrepo-Mendez, Laura C.; Martinez-Gutierrez, Marlen; Betancur-Galvis, Liliana A.; Marín García, Mª Luisa (American Chemical Society, 2022-08-26)
    [EN] Viral infections affect several million patients annually. Although hundreds of viruses are known to be pathogenic, only a few can be treated in the clinic with available antiviral drugs. Naturally based pharmacotherapy ...
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    Biological Profiling of Semisynthetic C19-Functionalized Ferruginol and Sugiol Analogues 
    González-Cardenete, Miguel A; Rivas, Fatima; Basset, Rachel; Stadler, Marco; Hering, Steffen; Padrón, José M.; Zaragozá, Ramón J.; Dea-Ayuela, Maria Auxiliadora (MDPI AG, 2021-02)
    [EN] The abietane-type diterpenoids are significant bioactive compounds exhibiting a varied range of pharmacological properties. In this study, the first synthesis and biological investigation of the new abietane-diterpenoid ...
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    Synthesis and antileishmanial activity of C7-and C12-functionalized dehydroabietylamine derivatives 
    Dea-Ayuela, M. Auxiliadora; Bilbao-Ramos, Pablo; Bolás-Fernández, Francisco; González-Cardenete, Miguel A (Elsevier, 2016-10-04)
    Abietane-type diterpenoids, either naturally occurring or synthetic, have shown a wide range of pharmacological actions, including antiprotozoal properties. In this study, we report on the antileishmanial evaluation of a ...