- -

Browsing by Subject "Anticancer drug"

RiuNet: Institutional repository of the Polithecnic University of Valencia

Browsing by Subject "Anticancer drug"

Sort by: Order: Results:

  • thumb
    Cellular photo(geno)toxicity of gefitinib after biotransformation 
    El Ouardi, Meryem; Tamarit-Mayo, Lorena; Vayá Pérez, Ignacio; Miranda, Miguel A.; Andreu, Inmaculada (Frontiers Media SA, 2023-06-07)
    [EN] Gefitinib (GFT) is a selective epidermal growth factor receptor (EGFR) inhibitor clinically used for the treatment of patients with non-small cell lung cancer. Bioactivation by mainly Phase I hepatic metabolism leads ...
  • thumb
    In vitro assessment of the photo(geno)toxicity associated with Lapatinib, a Tyrosine Kinase inhibitor 
    García-Laínez, G.; Vayá Pérez, Ignacio; Marín, Mª Pilar; Miranda Alonso, Miguel Ángel; Andreu Ros, María Inmaculada (Springer-Verlag, 2021-01)
    [EN] The epidermal growth factor receptors EGFR and HER2 are the main targets for tyrosine kinase inhibitors (TKIs). The quinazoline derivative lapatinib (LAP) is used since 2007 as dual TKI in the treatment of metastatic ...