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Browsing by Subject "Blood-brain barrier opening"

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First in-vivo Demonstration of Bilateral Blood-Brain Barrier Opening Using Acoustic Holograms in Mice

Jiménez-Gambín, Sergio; Jimenez, Noe; Benlloch Baviera, Jose María; Camarena Femenia, Francisco; Pouliopoulos, Antonios N.; Konofagou, Elisa E. (IEEE, 2020-09-11)

[EN] Focused ultrasound (FUS) with microbubbles allows for non-invasive targeted drug delivery into the central nervous system (CNS) by temporally and locally disrupting the bloodbrain barrier (BBB). However, current FUS ...
Multifocal acoustic holograms for deep-brain neuromodulation and BBB opening

Andrés, Diana; Jiménez-Gambín, Sergio; Jimenez, Noe; Camarena Femenia, Francisco (IEEE, 2020-09-11)

[EN] Single-element focused ultrasound devices have demonstrated its ability to non-invasively open the Blood Brain Barrier. However, skull irregularities and absorption produce strong aberrations in the ultrasound focus. ...
Numerical Study of Acoustic Holograms for Deep-Brain Targeting through the Temporal Bone Window

Andrés, Diana; Jimenez, Noe; Benlloch Baviera, Jose María; Camarena Femenia, Francisco (Elsevier, 2022-05)

[EN] Acoustic holograms can encode complex wavefronts to compensate the aberrations of a therapeutical ultrasound beam propagating through heterogeneous tissues such as the skull, and simultaneously, they can generate ...
Transcranial Ultrasound Holograms for the Blood-Brain Barrier Opening

Jiménez Gambín, Sergio (Universitat Politècnica de València, 2021-09-02)

[ES] El tratamiento de enfermedades neurológicas está muy limitado por la ineficiente penetración de los fármacos en el tejido cerebral dañado debido a la barrera hematoencefálica (BHE), lo que imposibilita mejorar la salud ...

Now showing items 1-4 of 4

Browsing by Subject "Blood-brain barrier opening"

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Browsing by Subject "Blood-brain barrier opening"