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Acetylcholinesterase-Capped Mesoporous Silica Nanoparticles That Open in the Presence of Diisopropylfluorophosphate (a Sarin or Soman Simulant)

Pascual, Lluís; El Sayed Shehata Nasr, Sameh; Martínez-Máñez, Ramón; Costero Nieto, Ana María; Gil Grau, Salvador; Gaviña Costero, Pablo; Sancenón Galarza, Félix (American Chemical Society, 2016-11-04)

Mesoporous silica nanoparticles loaded with rhodamine B and capped with acetylcholinesterase are able to be selectively opened and deliver their cargo in the presence of nerve agent simulant diisopropyl fluorophosphate (DFP).
Incorporation of Mesoporous Silica Particles in Gelatine Gels: Effect of Particle Type and Surface Modification on Physical Properties

Pérez-Esteve, Édgar; Oliver Hernández, Laura; García López, Laura; Nieuwland, Maaike; de Jongh, Harmen H. J.; Martínez-Máñez, Ramón; Barat Baviera, José Manuel (American Chemical Society, 2014-06-17)

The aim of this work was to investigate the impact of mesoporous silica particles (MSPs) on the physicochemical properties of filled protein gels. We have studied the effect of the addition of different mesoporous silica ...
Toward the Design of Smart Delivery Systems Controlled by Integrated Enzyme-Based Biocomputing Ensembles

Díez, Paula; Sanchez, Alfredo; Gamella, María; Paloma Martinez-Ruiz; Aznar, Elena; De La Torre, Cristina; Murguía, Jose R.; Martínez-Máñez, Ramón; Villalonga, Reynaldo; Pingarrón, J.M. (American Chemical Society, 2014)

We report herein the design of a smart delivery system in which cargo delivery from capped mesoporous silica (MS) nanoparticles is controlled by an integrated enzyme-based control unit . The system consists of Janus-type ...
Toxicological properties of two fluorescent carbon quantum dots with onion ring morphology and their usefulness as bioimaging agents

Blas García, Ana; Baldovi, Herme G.; Polo, Miriam; Victor, Victor M; García Gómez, Hermenegildo; Herance Camacho, Jose Raul (Royal Society of Chemistry, 2016)

In the present work, two carbon quantum dots with onion ring morphology, C-NOR and C-NOR(Eu) with an average size of 40 nm differing in the absence or presence of Eu3+ as Lewis acids during their preparation were synthesized ...

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Browsing by Subject "DRUG-DELIVERY"

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