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Acetylcholinesterase-Capped Mesoporous Silica Nanoparticles That Open in the Presence of Diisopropylfluorophosphate (a Sarin or Soman Simulant)

Pascual, Lluís; El Sayed Shehata Nasr, Sameh; Martínez-Máñez, Ramón; Costero Nieto, Ana María; Gil Grau, Salvador; Gaviña Costero, Pablo; Sancenón Galarza, Félix (American Chemical Society, 2016-11-04)

Mesoporous silica nanoparticles loaded with rhodamine B and capped with acetylcholinesterase are able to be selectively opened and deliver their cargo in the presence of nerve agent simulant diisopropyl fluorophosphate (DFP).
Gated mesoporous silica nanoparticles for the controlled delivery of drugs in cancer cells

Giménez Morales, Cristina; de la Torre, Cristina; Gorbe, Mónica; Aznar, Elena; Sancenón Galarza, Félix; Murguía, Jose R.; Martínez-Máñez, Ramón; Marcos Martínez, María Dolores; Amoros del Toro, Pedro Jose (American Chemical Society, 2015-03-31)

In recent years, mesoporous silica nanoparticles (MSNs) have been used as effective supports for the development of controlled-release nanodevices that are able to act as multifunctional delivery platforms for the encapsulation ...
Toward the Design of Smart Delivery Systems Controlled by Integrated Enzyme-Based Biocomputing Ensembles

Díez, Paula; Sanchez, Alfredo; Gamella, María; Paloma Martinez-Ruiz; Aznar, Elena; De La Torre, Cristina; Murguía, Jose R.; Martínez-Máñez, Ramón; Villalonga, Reynaldo; Pingarrón, J.M. (American Chemical Society, 2014)

We report herein the design of a smart delivery system in which cargo delivery from capped mesoporous silica (MS) nanoparticles is controlled by an integrated enzyme-based control unit . The system consists of Janus-type ...

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Browsing by Subject "GUEST MOLECULES"

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