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Browsing by Subject "Inflammation"

Now showing items 1-20 of 33

A possible use of melatonin in the dental field: Protein adsorption and in vitro cell response on coated titanium

Cerqueira, Andreia; Romero-Gavilán, Francisco; Araujo-Gomes, Nuno; García-Arnáez, Iñaki; Martínez-Ramos, Cristina; Ozturan, Seda; Azkargorta, Mikel; Elortza, Félix; Gurruchaga, Mariló; Suay, Julio; Goñi, Isabel (Elsevier BV, 2020-11)

[EN] Melatonin (MLT) is widely known for regulating the circadian cycles and has been studied for its role in bone regeneration and inflammation. Its application as a coating for dental implants can condition the local ...
Almond milk fermented with different potentially probiotic bacteria improves iron uptake by intestinal epithelial (Caco-2) cells

Bernat Pérez, Neus; Cháfer Nácher, María Teresa; Chiralt, A.; Laparra Llopis, José Moisés; González Martínez, María Consuelo (ISEKI Food Association (IFA), 2015)

[EN] New fermented almond milks were developed by using different potentially probiotic bacteria in order to cover the current demand for health-versatile non-dairy products. An in vitro digestion/Caco-2 cell model was ...
Alternaciones a nivel intestinal de lubinas alimentadas con bajos niveles de harina de pescado

Soler Luque, Zaida (Universitat Politècnica de València, 2019-09-02)

[ES] La necesidad de una mayor producción de harina de pescado para satisfacer la actual demanda en el mercado, así como su elevado coste, ha puesto de manifiesto la necesidad de buscar fuentes proteicas alternativas más ...
An LPS based method to stimulate the inflammatory response in growing rabbits

Knudsen, C.; Combes, S.; Mousavikhorshidi, H.; Oswald, I.; Gidenne, T. Noël (Editorial Universitat Politècnica de València, 2016-03-22)

[EN] Reliable indicators are needed to study the relationship between the inflammatory response of the growing rabbit and breeding factors such as feeding practices. A lipopolysaccharide (LPS) stimulation of the inflammatory ...
Complementary roles of mechanotransduction and inflammation in vascular homeostasis

Latorre, Marcos; Spronck, Bart; Humphrey, Jay D. (The Royal Society, 2021-01-27)

[EN] Arteries are exposed to relentless pulsatile haemodynamic loads, but via mechanical homeostasis they tend to maintain near optimal structure, properties and function over long periods in maturity in health. Numerous ...
Computational modeling predicts immuno-mechanical mechanisms of maladaptive aortic remodeling in hypertension

Latorre, Marcos; Bersi, Matthew R.; Humphrey, Jay D. (Elsevier, 2019-08)

[EN] Uncontrolled hypertension is a major risk factor for myriad cardiovascular diseases. Among its many effects, hypertension increases central artery stiffness which in turn is both an initiator and indicator of disease. ...
Consumo de alcohol y alteraciones en la composición de la microbiota intestinal: papel de los receptores del sistema inmunitario TLRs (Toll-Like receptors)

Rodríguez Navarro, Irene (Universitat Politècnica de València, 2020-10-07)

[ES] El alcohol es un compuesto neurotóxico causante del 5,3% de las muertes anuales. Un consumo excesivo de este afecta a un gran número de órganos y tejidos, especialmente el hígado, el sistema nervioso central (SNC) y ...
Diseño y optimización de biomodelos para el estudio de la sepsis

Dolz Andrés, Enric (Universitat Politècnica de València, 2023-10-03)

[ES] La sepsis es una condición sistémica grave que se caracteriza por una respuesta extrema del sistema inmunitario contra un agente patógeno, normalmente ocurre por una infección bacteriana que acaba llegando a la sangre, ...
Disfuncionalidad del IFN-I e implicación en el desarrollo del Síndrome de Liberación de Citoquinas (CRS) en casos severos de COVID-19

Alvarado Añón, Luna (Universitat Politècnica de València, 2021-07-22)

[ES] La aparición del brote de la enfermedad COVID-19 a finales del año 2019, unida a su rápida capacidad de transmisión provocó que, en cuestión de pocos meses, el mundo se viese sumido en una pandemia cuyo principal ...
Efecto de la dieta sobre la respuesta intestinal a un reto bacteriano en dorada (Sparus aurata, L.): Ensayo in vitro

Trujillo Martínez, Irene (Universitat Politècnica de València, 2018-09-18)

[ES] El creciente coste y limitada disponibilidad de la harina de pescado empleada en las formulaciones de los piensos acuícolas, ha promovido la necesidad de buscar nuevas estrategias, en relación a la dieta de los ...
Efectos de la radiación ultravioleta en líneas celulares humanas de la piel

Cartujo Cañal, Andrea (Universitat Politècnica de València, 2020-06-26)

[ES] La piel humana está continuamente expuesta a la radiación ultravioleta (UVR) solar. Esta exposición de la piel a la UVR genera gran variedad de respuestas biológicas que se van acumulando con el tiempo, incluyendo ...
El estrés oxidativo generado por etanol activa una respuesta inflamatoria en el epitelio pigmentario de la retina

Vidal Gil, Lorena (Universitat Politècnica de València, 2020-06-23)

[ES] El epitelio pigmentario de la retina (EPR) es el tejido implicado en la supervivencia y función de los fotorreceptores y de la coroides. Estudios previos ¿in vivo¿ e ¿in vitro¿ han demostrado que el estrés oxidativo ...
Estudio de los mecanismos implicados en la actividad anti-inflamatoria a nivel arterial del exenatida

Martínez de Marañón Peris, Aranzazu (Universitat Politècnica de València, 2016-06-30)

[EN] Introduction and Objectives: Exenatida is a glucagon-like peptide 1 (GLP-1) analog that is used in the treatment of type 2 diabetes (T2D). However, recent observations suggest that in addition to its antidiabetic ...
Evaluation of the inflammatory responses to sol-gel coatings with distinct biocompatibility levels

Cerqueira, Andreia; Araújo-Gomes, Nuno; Zhang, Yang; van den Beucken, Jeroen J. J. P.; Martínez-Ramos, Cristina; Ozturan, Seda; Izquierdo, Raúl; Muriach, Maria; Romero-Cano, Ricard; Baliño, Pablo; Romero-Gavilán, Francisco J. (John Wiley & Sons, 2021-09)

[EN] The immune system plays a crucial role in determining the implantation outcome, and macrophages are in the frontline of the inflammatory processes. Further, cellular oxidative stress resulting from the material ...
Excessive adventitial stress drives inflammation-mediated fibrosis in hypertensive aortic remodelling in mice

Spronck, Bart; Latorre, Marcos; Wang, Mo; Mehta, Sameet; Caulk, Alexander W.; Ren, Pengwei; Ramachandra, Abhay B.; Murtada, Sae-Il; Rojas, Alexia; He, Chang-Shun; Jiang, Bo; Bersi, Matthew R.; Tellides, George; Humphrey, Jay D. (The Royal Society, 2021-07-28)

[EN] Hypertension induces significant aortic remodelling, often adaptive but sometimes not. To identify immuno-mechanical mechanisms responsible for differential remodelling, we studied thoracic aortas from 129S6/SvEvTac ...
Extracellular vesicles: A new therapeutic strategy for joint conditions

Tofiño-Vian, Miguel; Guillen Salazar, Mª Isabel; Alcaraz Tormo, Mª Jose (Elsevier, 2018)

[EN] Extracellular vesicles (EVs) are attracting increasing interest since they might represent a more convenient therapeutic tool with respect to their cells of origin. In the last years much time and effort have been ...
Flexible Hybrid Electrodes for Continuous Measurement of the Local Temperature in Long-Term Wounds

Rodes-Carbonell, Ana María; Torregrosa-Valls, Juan; Guill Ibáñez, Antonio; Tormos Ferrando, Álvaro; Juan Blanco, María Aránzazu; Cebrián Ferriols, Antonio José (MDPI AG, 2021-04)

[EN] Long-term wounds need a continuous assessment of different biophysical parameters for their treatment, and there is a lack of affordable biocompatible devices capable of obtaining that uninterrupted flow of data. A ...
Gated nanomaterials as delivery platform for the treatment of inflammatory disorders

García Fernández, Alba (Universitat Politècnica de València, 2020-11-08)

[ES] La presente tesis doctoral titulada "Nanomateriales con puertas moleculares como plataforma de liberación controlada de fármacos para el tratamiento de desórdenes inflamatorios" se centra la preparación y evaluación ...
Genetic polymorphisms located in genes related to immune and inflammatory processes are associated with end-stage renal disease: a preliminary study

Jimenez-Sousa, Mª Angeles; López, Elisabeth; Fernandez-Rodriguez, Amanda; Tamayo, Eduardo; Fernández-Navarro, Pablo; Segura Roda, Laura; Heredia, Maria; Gómez-Herreras, José I.; Bustamante, Jesus; García Gómez, Juan Miguel; Bermejo-Martin, Jesus F.; Resino, Salvador (BioMed Central, 2012)

Background Chronic kidney disease progression has been linked to pro-inflammatory cytokines and markers of inflammation. These markers are also elevated in end-stage renal disease (ESRD), which constitutes a serious ...
Intestinal Explant Cultures from Gilthead Seabream (Sparus aurata, L.) Allowed the Determination of Mucosal Sensitivity to Bacterial Pathogens and the Impact of a Plant Protein Diet

Peñaranda, D.S.; Bäuerl, Christine; Tomas-Vidal, A.; Jover Cerda, Miguel; Estruch, Guillem; Pérez Martínez, Gaspar; Martínez-Llorens, Silvia (MDPI AG, 2020-10)

[EN] The interaction between diet and intestinal health has been widely discussed, although in vivo approaches have reported limitations. The intestine explant culture system developed provides an advantage since it reduces ...