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Browsing by Subject "Pharmacogenetics"

Now showing items 1-8 of 8

Análisis en tiempo real de datos farmacogenéticos de pacientes trasplantados

Barbosa Roa, German Darío (Universitat Politècnica de València, 2013-02-18)

[ES] En los últimos años diversos grupos médicos han realizado avances importantes en el campo de los trasplantes, logrando evitar en gran medida el rechazo agudo, pero tras el primer año, el éxito de los trasplantes no ...
Genotipado de polimorfimos de un único nucleótido relacionados con el tratamiento con curmarinas de enfermedades cardiovasculares

Sanchón Sánchez, Paula (Universitat Politècnica de València, 2017-09-08)

[ES] El acenocumarol ((RS)-4-hidroxi-3-[1-(4-nitrofenil)-3-oxobutil]cromen-2-ona) es un anticoagulante de la familia de las cumarinas comercializado como Sintrom. Su mecanismo de acción se basa en actuar como antagonista ...
Genotyping of single nucleotide polymorphisms related to attention-deficit hyperactivity disorder

Tortajada-Genaro, Luis Antonio; Mena-Mollá, Salvador; Niñoles Rodenes, Regina; Puigmule, Marta; Viladevall, Laia; Maquieira Catala, Ángel (Springer Verlag (Germany), 2016-03)

Pharmacological treatment of several diseases, such as attention-deficit hyperactivity disorder (ADHD), presents marked variability in efficiency and its adverse effects. The genotyping of specific single nucleotide ...
Isothermal-based DNA biosensors for application in pharmacogenetics

Yamanaka, Eric Seiti (Universitat Politècnica de València, 2020-07-21)

[EN] The determination of genetic biomarkers is progressively becoming more extended and popular, being commercialized even in kits for personalized medicine. Establishing specific genotype variations for each patient, ...
Learning of Pharmacogenetics in human medicine students through PBL and ICTs

Placencia Medina, Maritza Dorila; Silva Valencia, Javier; Garcia Bustamante, Carlos; Villarreal Valerio, Julian Anibal; Pando Álvarez, Rosa; Malca Casavilca, Michan; Contreras Pizarro, Carlos Heber (Editorial Universitat Politècnica de València, 2022-05-31)

[EN] Objective: To describe the learning achievement after training in pharmacogenetics based on PBL and ICT and its persistence four years later in human medicine students of a public university in Peru.Materials and ...
Metformin to treat Huntington disease: A pleiotropic drug against a multi-system disorder

Trujillo-Del Río, Cristina; Tortajada-Pérez, J.; Gómez-Escribano, A.P.; Casterá, F.; Peiró, C.; Millán, J.M.; Herrero, M.J.; Vázquez-Manrique, R.P. (Elsevier, 2022-06)

[EN] Huntington disease (HD) is a neurodegenerative disorder produced by an expansion of CAG repeats in the HTT gene. Patients of HD show involuntary movements, cognitive decline and psychiatric impairment. People carrying ...
Método para el genotipado de polimorfismo de único nucleótido relacionados con la administración del fármaco anticoagulante warfarina

León Sala, Teresa (Universitat Politècnica de València, 2015-10-22)

[EN] Oral anticoagulants are chronically taken by 1% and 2% of the population of the developed world. The most important is the warfarin (4-hydroxy-3-(3-oxo-1-phenylbutyl)-coumarin) because their effectiveness for ...
Personalized Medicine in Infant Population with Cancer: Pharmacogenetic Pilot Study of Polymorphisms Related to Toxicity and Response to Chemotherapy

Urtasun, Andrea; Olivera, Gladys G.; Sendra, Luis; Aliño, Salvador F.; Berlanga, Pablo; Gargallo, Pablo; Hervás-Marín, David; Balaguer, Julia; Juan-Ribelles, Antonio; Andrés, María del Mar; Cañete, Adela; Herrero, María José (MDPI AG, 2023-03)

[EN] Simple Summary Cancer is still the leading cause of disease-related death in pediatric populations and an important source of morbidity. These can be due to the neoplasm itself but also to the treatment administered; ...