RiuNet UPV Home
:
Browsing by Subject

Search RiuNet

Browse

All of RiuNet

My Account

RiuNet Help

Admin. UPV

Browsing by Subject "Tissue engineering"

Now showing items 1-20 of 58

A standardised approach to the biomechanical evaluation of tracheal grafts

Martínez-Hernández, Néstor J.; Más Estellés, Jorge; Milián-Medina, Lara; Martínez-Ramos, Cristina; Cerón-Navarro, José; Galbis-Caravajal, José; Roig-Bataller, Amparo; Mata-Roig, Manuel (MDPI AG, 2021-10)

[EN] The ideal tracheal substitute must have biomechanical properties comparable to the native trachea, but currently there is no standardised approach to evaluating these properties. Here we propose a novel method for ...
A tough act to follow: collagen hydrogel modifications to improve mechanical and growth factor loading capabilities

Sarrigiannidis, S.O.; Rey, J. M.; Dobre, O .; González-García, C.; Dalby, M.J.; Salmerón Sánchez, Manuel (Elsevier, 2021-03)

[EN] Collagen hydrogels are among the most well-studied platforms for drug delivery and in situ tissue engineering, thanks to their low cost, low immunogenicity, versatility, biocompatibility, and similarity to the natural ...
Alginate-Agarose Hydrogels Improve the In Vitro Differentiation of Human Dental Pulp Stem Cells in Chondrocytes. A Histological Study

Oliver-Ferrándiz, María; Milián, Lara; Sancho-Tello, María; Martín de Llano, José Javier; Gisbert-Roca, Fernando; Martínez-Ramos, Cristina; Carda, Carmen; Mata, Manuel (MDPI AG, 2021-07)

[EN] Matrix-assisted autologous chondrocyte implantation (MACI) has shown promising results for cartilage repair, combining cultured chondrocytes and hydrogels, including alginate. The ability of chondrocytes for MACI is ...
An experimental fatigue study of a porous scaffold for the regeneration of articular cartilage

Vikingsson, Line Karina Alva; Gómez-Tejedor, José Antonio; Gallego Ferrer, Gloria; Gómez Ribelles, José Luís (Elsevier, 2015-05-01)

The aim of this experimental study is to predict the long-term mechanical behavior of a porous scaffold implanted in a cartilage defect for tissue engineering purpose. Fatigue studies were performed by up to 100,000 ...
Aplicación de la terapia basada en exosomas con biomateriales en la regeneración del Sistema Nervioso Central

Roldán Herrero, Daniel (Universitat Politècnica de València, 2021-02-04)

[ES] En este trabajo de final de máster, se propone la realización de una revisión bibliográfica sobre los exosomas empleados en ingeniería tisular para la aplicación en lesiones del sistema nervioso central (SNC). En dicha ...
BDNF-Gene Transfected Schwann Cell-Assisted Axonal Extension and Sprouting on New PLA-PPy Microfiber Substrates

Gisbert-Roca, Fernando; André, Franck M.; Más Estellés, Jorge; Monleón Pradas, Manuel; Mir, Lluis M.; Martínez-Ramos, Cristina (John Wiley & Sons, 2021-05)

[EN] The work here reported analyzes the effect of increased efficiency of brainderived neurotrophic factor (BDNF) production by electroporated Schwann cells (SCs) on the axonal extension in a coculture system on a biomaterial ...
Bio-Nanocomposite Hydrogel Based on Zinc Alginate/Graphene Oxide: Morphology, Structural Conformation, Thermal Behavior/Degradation, and Dielectric Properties

Sabater i Serra, Roser; Molina Mateo, José; Torregrosa Cabanilles, Constantino; Andrio-Balado, Andreu; Meseguer Dueñas, José María; Serrano-Aroca, Ángel (MDPI AG, 2020-03)

[EN] Bio-nanocomposite hydrogels based on sodium alginate (SA) as polymer matrix and graphene oxide (GO) nanosheets with zinc as crosslinking agent were synthesized with the aim of incorporating the intrinsic properties ...
Biohybrids for Neural Tracts Regeneration

Rodríguez Doblado, Laura (Universitat Politècnica de València, 2022-03-11)

[ES] Las lesiones del sistema nervioso que implican la interrupción de haces axonales son devastadoras para el individuo. La regeneración autónoma de los tractos axonales dañados o degenerados es poco frecuente, ya que ...
Biostable scaffolds of polyacrylate polymers implanted in the articular cartilage induce hyaline-like cartilage regeneration in rabbits

Sancho-Tello, María; Forriol, Francisco; Martín de Llano, José J.; Antolinos Turpín, Carmen María; Gómez-Tejedor, José-Antonio; Gómez Ribelles, José Luís; Carda, Carmen (Wichtig Publishing, 2017)

[EN] Purpose: To study the influence of scaffold properties on the organization of ¿in vivo¿ cartilage regeneration. Our hypothesis is that stress transmission to the cells seeded inside the scaffold pores or surrounding ...
Cell-free cartilage engineering approach using hyaluronic acid-polycaprolactone scaffolds: A study invivo

Lebourg, Myriam Madeleine; Martínez Díaz, S.; Garcia Giralt, Natalia; Torres Claramunt, R.; Gómez-Tejedor, José Antonio; Gómez Ribelles, José Luís; Vila Canet, G; Monllau, J.C. (SAGE Publications (UK and US), 2014-05)

Polycaprolactone scaffolds modified with cross-linked hyaluronic acid were prepared in order to establish whether a more hydrophilic and biomimetic microenvironment benefits the progenitor cells arriving from bone marrow ...
Compositional changes to synthetic biodegradable scaffolds modulate the influence of hydrostatic pressure on chondrogenesis of mesenchymal stem cells

Ródenas Rochina, Joaquín; Kelly, Daniel John; Gómez Ribelles, José Luís; Lebourg, Myriam Madeleine (IOP Publishing, 2016)

[EN] Mechanical cues such as hydrostatic pressure (HP) are known to regulate mesenchymal stem cell (MSC) differentiation. The fate of such cells is also strongly influenced by their substrate. The objective of this study ...
Computational methodology to determine fluid related parameters on non regular three-dimensional scaffolds

Acosta Santamaría, Víctor Andrés; Malvé, M.; Duizabo, A.; Mena Tobar, A.; Gallego Ferrer, Gloria; García Aznar, J.M.; Doblare Castellano, Manuel; Ochoa, I. (Springer Verlag (Germany), 2013-11)

The application of three-dimensional (3D) biomaterials to facilitate the adhesion, proliferation, and differentiation of cells has been widely studied for tissue engineering purposes. The fabrication methods used to ...
Conduits based on the combination of hyaluronic acid and silk fibroin: Characterization, in vitro studies and in vivo biocompatibility

Gisbert-Roca, Fernando; Lozano Picazo, Paloma; Pérez-Rigueiro, José; Guinea Tortuero, Gustavo Victor; Monleón Pradas, Manuel; Martínez-Ramos, Cristina (Elsevier, 2020-04-01)

[EN] We address the production of structures intended as conduits made from natural biopolymers, capable of promoting the regeneration of axonal tracts. We combine hyaluronic acid (HA) and silk fibroin (SF) with the aim ...
Creating the bioartificial myocardium for cardiac repair: challenges and clinical targets

Chachques, Juan C.; Monleón Pradas, Manuel; Bayes-Genis, Antoni; Semino, Carlos (Taylor & Francis, 2013)

[EN] The association of stem cells with tissue-engineered scaffolds constitutes an attractive approach for the repair of myocardial tissue with positive effects to avoid ventricular chamber dilatation, which changes from ...
Crosslinked fibrin gels for tissue engineering: Two approaches to improve their properties

Gamboa-Martinez, Tatiana Carolina; Luque-Guillen, Victoria; González-García, Cristina; Gómez Ribelles, José Luís; Gallego Ferrer, Gloria (John Wiley & Sons, 2015)

[EN] Fibrin is a protein that can be used as an ideal scaffolding material to promote tissue regeneration. In order to enhance its physical properties in this study a natural crosslinker, genipin (GP), was employed with ...
Culture of human bone marrow-derived mesenchymal stem cells on of poly(L-lactic acid) scaffolds: potential application for the tissue engineering of cartilage

Izal, Iñigo; Aranda, Pablo; Sanz Ramos, Patricia; Ripalda, Purificacion; Mora, Gonzalo; Granero Molto, Froilan; Deplaine, Harmony; Gómez Ribelles, José Luís; Gallego Ferrer, Gloria; Acosta, Victor; Ochoa, Ignacio; García Aznar, Manuel; Andreu, Enrique J.; Monleón Pradas, Manuel; Doblare Castellano, Manuel; Prosper, Felipe (Springer Verlag, 2013-08)

Due to the attractive properties of poly(l-lactic acid) (PLLA) for tissue engineering, the aim was to determine the growth and differentiation capacity of mesenchymal stromal cells (MSCs) in PLLA scaffolds and their potential ...
Desarrollo de membranas basadas en policaprolactona, ácido poliláctico y sus mezclas, cargadas con curcumina, mediante electrohilado uni- y co-axial para aplicaciones en Ingeniería Tisular

Olivas Alonso, Carmen (Universitat Politècnica de València, 2020-07-13)

[ES] La Ingeniería Tisular actualmente trata de combinar biomateriales y moléculas biológicamente activas a liberar con el fin de influir y alterar el comportamiento celular, ofreciendo la posibilidad de tratar enfermedades ...
Desarrollo de microgeles basados en microcápsulas huecas para generar modelos de enfermedad de mieloma múltiple

García Briega, María Inmaculada (Universitat Politècnica de València, 2021-09-29)

[ES] El proyecto tiene como objetivo producir, caracterizar y validar una plataforma de cultivo in vitro para reproducir el comportamiento in vivo de las células tumorales de Mieloma Múltiple e investigar la influencia de ...
Desarrollo de scaffolds semidegradables de matriz de poli(ε-caprolactona)/poli(etil acrilato) como sistemas de contención tisular

Ewertowska, Elzbieta (Universitat Politècnica de València, 2016-05-19)

[EN] Nowadays, numerous technologies from the field of tissue engineering are in continuous development of new different biomaterials with one goal to adapt each product to the specific need of one individual. Taking into ...
Desarrollo de un dispositivo para estimulación eléctrica de células neurales in vitro

García Jiménez, Irene (Universitat Politècnica de València, 2020-09-08)

[ES] La problemática asociada a las patologías del sistema nervioso viene del limitado potencial de regeneración de los tejidos nerviosos, y especialmente del SNC. Las lesiones en estos tejidos suponen un importante problema ...