Rodrigo Tarrega, Guillermo; Carrera Montesinos, Javier; Ruiz-Ferrer, Virginia; Del Toro, F.J.; Llave, C; Voinnet, O.; Elena Fito, Santiago Fco(Public Library of Science, 2012-07)
Understanding the mechanisms by which plants trigger host defenses in response to viruses has been a challenging problem owing to the multiplicity of factors and complexity of interactions involved. The advent of genomic ...
Alandes Esteve, Sandra(Universitat Politècnica de València, 2017-09-04)
The high throughput techniques such as microarrays and sequencing have boosted transcriptomic studies as approaches of interest in the biomedical areas. Its use has generated a large volume of biological information, ...
Debesa Tur, Gabriela Belén(Universitat Politècnica de València, 2016-11-03)
[EN] The causes of the development and evolution of cancerous processes are still unclear
among the scientific community; there is no deep understanding of this illness yet, due to
its high complexity and multifactorial ...
Botey Bataller, Francisco Javier(Universitat Politècnica de València, 2019-09-03)
[ES] La insuficiencia cardiaca (IC) es un síndrome multifactorial cuya incidencia y
prevalencia han aumentado en los últimos años. Sus principales etiologías, la miocardiopatía
isquémica y la miocardiopatía dilatada aún ...
Merelo, P.; Agusti, J.; Arbona, V.; Costa, M.L.; Hueso Estornell, Leandro; Gómez-Cadenas, Aurelio; Coimbra, S.; Gómez Jiménez, Maria Dolores; Perez Amador, Miguel Angel; Domingo, C.; Talón, M.; Tadeo, F.R.(Frontiers Media SA, 2017-02-08)
[EN] Abscission is a cell separation process by which plants can shed organs such as fruits, leaves, or flowers. The process takes place in specific locations termed abscission zones. In fruit crops like citrus, fruit ...
Baldé, A.; Neves, D.; García-Breijo, Francisco-José; Pais, M. S.; Cravador, A.(Springer (Biomed Central Ltd.), 2017)
[EN] Background: Phlomis plants are a source of biological active substances with potential applications in the control of phytopathogens. Phlomis purpurea (Lamiaceae) is autochthonous of southern Iberian Peninsula and ...
Tarazona Sánchez, Adrián(Universitat Politècnica de València, 2019-10-01)
[EN] In recent years the study of complex biological systems has changed in a radical way. This change has been promoted by two important breakthroughs. On the one hand, advances in high-throughput molecular biology that ...
Furió Tarí, Pedro(Universitat Politècnica de València, 2020-10-19)
[EN] Transcriptomics is one of the most important and relevant areas of bioinformatics. It allows detecting the genes that are expressed at a particular moment in time to explore the relation between genotype and phenotype. ...
Tarazona Campos, Sonia; García-Alcalde, Fernando; Dopazo, Joaquín; Ferrer Riquelme, Alberto José; Conesa, Ana(Cold Spring Harbor Laboratory Press, 2011-09-08)
Next-generation sequencing (NGS) technologies are revolutionizing genome research, and in particular, their application to transcriptomics (RNA-seq) is increasingly being used for gene expression profiling as a replacement ...
Bernabeu Gómez, Elena(Universitat Politècnica de València, 2016-07-28)
[EN] In recent years the omics disciplines have made their way across a wider spectrum of
research groups, thus leading to the generation of multi-omics data sets in a great number of
studies. While traditional omics ...
Tarazona Campos, Sonia(Universitat Politècnica de València, 2015-03-30)
La transcriptómica estudia el nivel de expresión de los genes en distintas condiciones experimentales para tratar de identificar los genes asociados a un fenotipo dado así como las relaciones de regulación entre distintos ...
Background: Cucurbita pepo belongs to the Cucurbitaceae family. The "Zucchini" types rank among the highest-valued vegetables worldwide, and other C. pepo and related Cucurbita spp., are food staples and rich sources of ...
Naturil Alfonso, Carmen; Saenz de Juano Ribes, María de los Desamparados; Peñaranda, D.S.; Vicente Antón, José Salvador; Marco Jiménez, Francisco(Public Library of Science, 2012-12)
Parthenogenetic embryos are one attractive alternative as a source of embryonic stem cells, although many aspects related to the biology of parthenogenetic embryos and parthenogenetically derived cell lines still need to ...
[EN] The intrinsic characteristics of the tumor microenvironment (TME), including acidic pH and overexpression of hydrolytic enzymes, offer an exciting opportunity for the rational design of TME-drug delivery systems (DDS). ...
Marín Falco, Matías(Universitat Politècnica de València, 2015-10-22)
[EN] This TFG will compare a transcription facto database with gene expression data availables on different cancer types in order to find common regulation processes. To this aim, RNA-Seq files at the International Cancer ...
Cervera-Benet, Héctor; Ambros Palaguerri, Silvia; Bernet, Guillermo P.; Rodrigo Tarrega, Guillermo; Elena Fito, Santiago Fco(Oxford University Press, 2018-07)
[EN] Determining the fitness of viral genotypes has become a standard practice in virology as it is essential to evaluate their evolutionary potential. Darwinian fitness, defined as the advantage of a given genotype with ...