Gutiérrez, J.; Nieto, B.; Piqueras, P.; Ibañez Escriche, N.; Salgado, C. (2006). Genetic parameters for canalisation analysis of litter size and litter weight traits at birth in mice. Genetics Selection Evolution. 38(5):445-462. https://doi.org/10.1051/gse:2006014
Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/123194
Title:
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Genetic parameters for canalisation analysis of litter size and litter weight traits at birth in mice
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Author:
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Gutiérrez, J.P.
Nieto, B.
Piqueras, P.
Ibañez Escriche, Noelia
Salgado, C.
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UPV Unit:
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Universitat Politècnica de València. Departamento de Ciencia Animal - Departament de Ciència Animal
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Issued date:
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Abstract:
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[EN] The aim of this research was to explore the genetic parameters associated with environmental variability for litter size (LS), litter weight (LW) and mean individual birth weight (IW) in mice before canalisation. The ...[+]
[EN] The aim of this research was to explore the genetic parameters associated with environmental variability for litter size (LS), litter weight (LW) and mean individual birth weight (IW) in mice before canalisation. The analyses were conducted on an experimental mice population designed to reduce environmental variability for LS. The analysed database included 1976 records for LW and IW and 4129 records for LS. The total number of individuals included in the analysed pedigree was 3997. Heritabilities estimated for the traits under an initial exploratory approach varied from 0.099 to 0.101 for LS, from 0.112 to 0.148 for LW and from 0.028 to 0.033 for IW. The means of the posterior distribution of the heritability under a Bayesian approach were the following: 0.10 (LS), 0.13 (LW) and 0.03 (IW). In general, the heritabilities estimated under the initial exploratory approach for the environmental variability of the analysed traits were low. Genetic correlations estimated between the trait and its variability reached values of -0.929 (LS), -0.815 (LW) and 0.969 (IW). The results presented here for the first time in mice may suggest a genetic basis for variability of the evaluated traits, thus opening the possibility to be implemented in selection schemes.
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Subjects:
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Canalisation
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Variability
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Mice
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Litter size
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Litter weight
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Copyrigths:
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Reconocimiento (by)
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Source:
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Genetics Selection Evolution. (issn:
0999-193X
)
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DOI:
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10.1051/gse:2006014
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Publisher:
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Springer (Biomed Central Ltd.)
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Publisher version:
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http://doi.org/10.1051/gse:2006014
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Project ID:
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info:eu-repo/grantAgreement/UCM//PR1%2F03-11650/
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Thanks:
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This research was partially financed by a grant from the University Complutense of Madrid, n◦ UCM PR1/03-11650. We thank Dr. Félix Goyache for comments on the manuscript.
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Type:
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Artículo
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