Fernández Díaz, R.; Calero-Alcarria, MDS.; García Narbón, JV.; Reiviakine, I.; Arnau Vives, A.; Jiménez Jiménez, Y. (2021). A fast method for monitoring the shifts in resonance frequency and dissipation of the QCM sensors of a Monolithic array in biosensing applications. IEEE Sensors Journal. 21(5):6643-6651. https://doi.org/10.1109/JSEN.2020.3042653
Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/161161
Title:
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A fast method for monitoring the shifts in resonance frequency and dissipation of the QCM sensors of a Monolithic array in biosensing applications
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Author:
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FERNÁNDEZ DÍAZ, ROMÁN
Calero-Alcarria, María Del Señor
García Narbón, José Vicente
Reiviakine, Ilya
Arnau Vives, Antonio
Jiménez Jiménez, Yolanda
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UPV Unit:
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Universitat Politècnica de València. Departamento de Ingeniería Electrónica - Departament d'Enginyeria Electrònica
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Issued date:
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Abstract:
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[EN] Improvement of data acquisition rate remains as an important challenge in applications with Quartz Crystal Microbalance (QCM) technology where high throughput is required. To address this challenge, we developed a ...[+]
[EN] Improvement of data acquisition rate remains as an important challenge in applications with Quartz Crystal Microbalance (QCM) technology where high throughput is required. To address this challenge, we developed a fast method capable of measuring the response of a large number of sensors and/or overtones, with a high time resolution. Our method, which can be implemented in a low-cost readout electronic circuit, is based on the estimation of fr (frequency shift) and D (dissipation shift) from measurements of the sensor response obtained at a single driving frequency. By replacing slow fitting procedures with a direct calculation, the time resolution is only limited by the physical characteristics of the sensor (resonance frequency and quality factor), but not by the method itself. Capabilities of the method are demonstrated by monitoring multiple overtones with a single 5 MHz sensor and a Monolithic QCM array comprising 24 50MHz-sensors. Accuracy of the method is validated and compared with the state-of-the-art, as well as with a reference method based on impedance analysis.
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Subjects:
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Biosensor
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Fast acquisition
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Monolithic Quartz Crystal Microbalance (MQCM)
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Multiple overtones
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Sensor array devices
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Copyrigths:
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Reserva de todos los derechos
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Source:
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IEEE Sensors Journal. (issn:
1530-437X
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DOI:
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10.1109/JSEN.2020.3042653
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Publisher:
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Institute of Electrical and Electronics Engineers
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Publisher version:
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https://doi.org/10.1109/JSEN.2020.3042653
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Project ID:
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info:eu-repo/grantAgreement/EC/H2020/737212/EU/Capturing non-Amplified Tumor Circulating DNA with Ultrasound Hydrodynamics/
info:eu-repo/grantAgreement/MINECO//AGL2016-77702-R/ES/DISEÑO DE UN BIOSENSOR DE ADN BASADO EN TECNOLOGIA HFF-QCM PARA LA DETECCION DE SUSTANCIAS ADULTERANTES EN MIEL/
info:eu-repo/grantAgreement/AEI//BES-2017-080246/
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Description:
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© 2021 IEEE. Personal use of this material is permitted. Permissíon from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertisíng or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
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Thanks:
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This work was supported in part by the Ministerio de Economía, Industria y Competitividad de España-Agencia Estatal de Investigación with Fondo Europeo de Desarrollo Regional (FEDER) Funds under Grant AGL2016-77702-R and ...[+]
This work was supported in part by the Ministerio de Economía, Industria y Competitividad de España-Agencia Estatal de Investigación with Fondo Europeo de Desarrollo Regional (FEDER) Funds under Grant AGL2016-77702-R and in part by the European Commission Horizon 2020 Programme (Capturing non-amplified tumor circulating DNA with ultrasound hydrodynamics) under Agreement H2020-FETOPEN-2016-2017/737212-CATCH-UDNA. The work of María Calero was supported by the Spanish Ministry of Economy, Industry and Competitiveness, Madrid, Spain, under Grant BES-2017-080246.
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Type:
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Artículo
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