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Enhancing timing performance of heterostructures with double-sided readout

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Enhancing timing performance of heterostructures with double-sided readout

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dc.contributor.author Pagano, Fiammetta es_ES
dc.contributor.author Kratochwil, Nicolaus es_ES
dc.contributor.author Lowis, Carsten es_ES
dc.contributor.author Choong, Woon-Seng es_ES
dc.contributor.author Paganoni, Marco es_ES
dc.contributor.author Pizzichemi, Marco es_ES
dc.contributor.author Cates, Joshua W. es_ES
dc.contributor.author Auffray, Etiennette es_ES
dc.date.accessioned 2024-10-21T18:03:05Z
dc.date.available 2024-10-21T18:03:05Z
dc.date.issued 2024-10-21 es_ES
dc.identifier.issn 0031-9155 es_ES
dc.identifier.uri http://hdl.handle.net/10251/210641
dc.description.abstract [EN] Objective. Heterostructured scintillators offer a promising solution to balance the sensitivity and timing in TOF-PET detectors. These scintillators utilize alternating layers of materials with complementary properties to optimize performance. However, the layering compromises time resolution due to light transport issues. This study explores double-sided readout-enabling improved light collection and Depth-of-Interaction (DOI) information retrieval-to mitigate this effect and enhance the timing capabilities of heterostructures. Approach. The time resolution and DOI performances of 3 x 3 x 20 mm3 BGO&EJ232 heterostructures were assessed in a single and double-sided readout (SSR and DSR, respectively) configuration using high-frequency electronics. Main results. Selective analysis of photopeak events yielded a DOI resolution of 6.4 +/- 0.04 mm. Notably, the Coincidence Time Resolution (CTR) improved from 262 +/- 8 ps (SSR) to 174 +/- 6 ps (DSR) when measured in coincidence with a fast reference detector. Additionally, symmetrical configuration of two identical heterostructures in coincidence was tested, yielding in DSR a CTR of 254 +/- 8 ps for all photopeak events and 107 +/- 5 ps for the fastest events. Significance. By using high-frequency double-sided readout, we could measure DOI resolution and improve the time resolution of heterostructures of up to 40%. The DOI information resulted intrinsically captured in the average between the timestamps of the two SiPMs, without requiring any further correction. es_ES
dc.description.sponsorship This work was carried out in the frame of the Crystal Clear Collaboration. It received support from the CERN Budget for Knowledge Transfer to Medical Applications and from the Wolfgang Gentner Programme of the German Federal Ministry of Education and Research (Grant No. 13E18CHA). Some material was based upon work supported by the National Institutes of Health under research Grant R01EB028286. The authors would like to thank Isabel Frank for her help in the preparation of the mechanics for the experimental setup. es_ES
dc.language Inglés es_ES
dc.publisher IOP Publishing es_ES
dc.relation.ispartof Physics in Medicine and Biology es_ES
dc.rights Reconocimiento (by) es_ES
dc.subject Time-of-flight PET es_ES
dc.subject Coincidence time resolution es_ES
dc.subject Heterostructured scintillators es_ES
dc.subject Depth of interaction es_ES
dc.subject High-frequency es_ES
dc.subject Double-sided readout es_ES
dc.title Enhancing timing performance of heterostructures with double-sided readout es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1088/1361-6560/ad7fc8 es_ES
dc.relation.projectID info:eu-repo/grantAgreement/BMBF//13E18CHA/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/NIH//R01EB028286/ es_ES
dc.rights.accessRights Abierto es_ES
dc.description.bibliographicCitation Pagano, F.; Kratochwil, N.; Lowis, C.; Choong, W.; Paganoni, M.; Pizzichemi, M.; Cates, JW.... (2024). Enhancing timing performance of heterostructures with double-sided readout. Physics in Medicine and Biology. 69(20). https://doi.org/10.1088/1361-6560/ad7fc8 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.1088/1361-6560/ad7fc8 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 69 es_ES
dc.description.issue 20 es_ES
dc.identifier.pmid 39321964 es_ES
dc.relation.pasarela S\529031 es_ES
dc.contributor.funder National Institutes of Health, EEUU es_ES
dc.contributor.funder Bundesministerium für Bildung und Forschung, Alemania es_ES


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