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Development of AIDA v4.3b diabetes simulator: Technical upgrade to support incorporation of lispro, aspart, and glargine insulin analogues

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Development of AIDA v4.3b diabetes simulator: Technical upgrade to support incorporation of lispro, aspart, and glargine insulin analogues

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dc.contributor.author Lehmann, Eldon D. es_ES
dc.contributor.author Tarín, Cristina es_ES
dc.contributor.author Bondía Company, Jorge es_ES
dc.contributor.author Teufel, Edgar es_ES
dc.contributor.author Deutsch, Tibor es_ES
dc.date.accessioned 2015-03-10T13:41:22Z
dc.date.available 2015-03-10T13:41:22Z
dc.date.issued 2011
dc.identifier.issn 0840-8688
dc.identifier.uri http://hdl.handle.net/10251/47929
dc.description.abstract Introduction. AIDA is an interactive educational diabetes simulator available on the Internet without charge since 1996 (accessible at: http://www.2aida.org/). Since the program’s original release, users have developed new requirements, with new operating systems coming into use and more complex insulin management regimens being adopted. The current work has aimed to design a comprehensive diabetes simulation system from both a clinical and information technology perspective. Methods. A collaborative development is taking place with a new generic model of subcutaneous insulin absorption, permitting the simulation of rapidly-acting and very long-acting insulin analogues, as well as insulin injections larger than 40 units. This novel, physiological insulin absorption model has been incorporated into AIDA v4. Technical work has also been undertaken to install and operate the AIDA software within a DOSBox emulator, to ensure compatibility with Windows XP, Vista and 7 operating systems as well as Apple Macintosh computers running Parallels PC emulation software. Results. Plasma insulin simulations are demonstrated following subcutaneous injections of a rapidly-acting insulin analogue, a short-acting insulin preparation, intermediate-acting insulin, and a very long-acting insulin analogue for injected insulin doses up to 60 units of insulin. Discussion. The current work extends the useful life of the existing AIDA v4 program. es_ES
dc.language Inglés es_ES
dc.publisher Hindawi Publishing Corporation es_ES
dc.relation.ispartof Journal of Electrical and Computer Engineering es_ES
dc.rights Reconocimiento (by) es_ES
dc.subject Diabeter simulator es_ES
dc.subject Interative educational software es_ES
dc.subject Intermediate-acting insulin es_ES
dc.subject.classification INGENIERIA DE SISTEMAS Y AUTOMATICA es_ES
dc.title Development of AIDA v4.3b diabetes simulator: Technical upgrade to support incorporation of lispro, aspart, and glargine insulin analogues es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1155/2011/427196
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Instituto Universitario de Automática e Informática Industrial - Institut Universitari d'Automàtica i Informàtica Industrial es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Ingeniería de Sistemas y Automática - Departament d'Enginyeria de Sistemes i Automàtica es_ES
dc.description.bibliographicCitation Lehmann, ED.; Tarín, C.; Bondía Company, J.; Teufel, E.; Deutsch, T. (2011). Development of AIDA v4.3b diabetes simulator: Technical upgrade to support incorporation of lispro, aspart, and glargine insulin analogues. Journal of Electrical and Computer Engineering. 2011:1-17. doi:10.1155/2011/427196 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://dx.doi.org/10.1155/2011/427196 es_ES
dc.description.upvformatpinicio 1 es_ES
dc.description.upvformatpfin 17 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 2011 es_ES
dc.relation.senia 216116
dc.identifier.eissn 2090-0155
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