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Generation of realistic atrial to atrial interval series during atrial fibrillation

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Generation of realistic atrial to atrial interval series during atrial fibrillation

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dc.contributor.author Climent, Andreu M. es_ES
dc.contributor.author Atienza, Felipe es_ES
dc.contributor.author Millet Roig, José es_ES
dc.contributor.author Guillem Sánchez, María Salud es_ES
dc.date.accessioned 2016-01-08T13:52:22Z
dc.date.available 2016-01-08T13:52:22Z
dc.date.issued 2011-11
dc.identifier.issn 0140-0118
dc.identifier.uri http://hdl.handle.net/10251/59568
dc.description.abstract The aim of the this study is to describe a methodological architecture for the generation of realistic atrial to atrial activation intervals (AA) during atrial fibrillation (AF), which can be used to investigate the role of the fibrillatory process in the ventricular response during AF. In this study, a methodology for the generation of AA interval series with a desired probability density function and autocorrelation function is presented. The methodology was evaluated on 2000 AA interval series from 20 endocardial recordings. The results showed that synthetic AA series presented the same statistical characteristics as the real AA series, with a correlation higher than 0.94 (P < 0.01) for all measured statistical parameters. In addition, the role of each statistical characteristic of the AA interval series in the ventricular response during AF is examined using a mathematical model of the atrioventricular node. The statistical characteristics of the AA series influenced the position of more probable RR intervals and the shape of the RR histogram, demonstrating the importance of an accurate characterization and generation of AA interval series during AF. The use of the present methodology may help in understanding the role of the atrial fibrillatory process in the ventricular response during AF. es_ES
dc.description.sponsorship This research was supported by Spanish Ministry of Education and Science under TEC2009-13939; the Universitat Politecnica de Valencia through its research initiative program; and the Spanish Society of Cardiology. en_EN
dc.language Inglés es_ES
dc.publisher Springer Verlag (Germany) es_ES
dc.relation.ispartof Medical and Biological Engineering and Computing es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Atrioventricular conduction es_ES
dc.subject Pearson type IV es_ES
dc.subject Rate control es_ES
dc.subject Statistical modeling es_ES
dc.subject.classification TECNOLOGIA ELECTRONICA es_ES
dc.title Generation of realistic atrial to atrial interval series during atrial fibrillation es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1007/s11517-011-0823-2
dc.relation.projectID info:eu-repo/grantAgreement/MICINN//TEC2009-13939/ES/Desarrollo De Tecnicas Avanzadas De Analisis Y Caracterizacion De Mapas De Propagacion Para La Ayuda Al Diagnostico Electrocardiografico/ es_ES
dc.rights.accessRights Cerrado es_ES
dc.contributor.affiliation Universitat Politècnica de València. Instituto Universitario de Aplicaciones de las Tecnologías de la Información - Institut Universitari d'Aplicacions de les Tecnologies de la Informació es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Ingeniería Electrónica - Departament d'Enginyeria Electrònica es_ES
dc.description.bibliographicCitation Climent, AM.; Atienza, F.; Millet Roig, J.; Guillem Sánchez, MS. (2011). Generation of realistic atrial to atrial interval series during atrial fibrillation. Medical and Biological Engineering and Computing. 49(11):1261-1268. doi:10.1007/s11517-011-0823-2 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://dx.doi.org/10.1007/s11517-011-0823-2 es_ES
dc.description.upvformatpinicio 1261 es_ES
dc.description.upvformatpfin 1268 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 49 es_ES
dc.description.issue 11 es_ES
dc.relation.senia 208801 es_ES
dc.contributor.funder Universitat Politècnica de València es_ES
dc.contributor.funder Sociedad Española de Cardiología es_ES
dc.contributor.funder Ministerio de Ciencia e Innovación
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