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Interaction between acrylic substrates and RAD16-I peptide in its self-assembling

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Interaction between acrylic substrates and RAD16-I peptide in its self-assembling

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dc.contributor.author Arnal Pastor, María Pilar es_ES
dc.contributor.author González-Mora, Debora es_ES
dc.contributor.author García-Torres, Fernando es_ES
dc.contributor.author Monleón Pradas, Manuel es_ES
dc.contributor.author Vallés Lluch, Ana es_ES
dc.date.accessioned 2017-05-12T07:23:04Z
dc.date.available 2017-05-12T07:23:04Z
dc.date.issued 2016-08-02
dc.identifier.issn 1022-9760
dc.identifier.uri http://hdl.handle.net/10251/81033
dc.description.abstract [EN] Self-assembling peptides (SAP) are widely used as scaffolds themselves, and recently as fillers of microporous scaffolds, where the former provides a cell-friendly nanoenvironment and the latter improves its mechanical properties. The characterization of the interaction between these short peptides and the scaffold material is crucial to assess the potential of such a combined system. In this work, the interaction between poly(ethyl acrylate) (PEA) and 90/10 ethyl acrylate-acrylic acid copolymer P(EAcoAAc) with the SAP RAD16-I has been followed using a bidimensional simplified model. By means of the techniques of choice (congo red staining, atomic force microscopy (AFM), and contact angle measurements) the interaction and self-assembly of the peptide has proven to be very sensitive to the wettability and electro-negativity of the polymeric substrate. es_ES
dc.description.sponsorship The authors acknowledge funding through the European Commission FP7 project RECATABI (NMP3-SL-2009-229239), and from the Spanish Ministerio de Ciencia e Innovacion through projects MAT2011-28791-C03-02 and -03. This work was also supported by the Spanish Ministerio de Educacion through M. Arnal-Pastor FPU 2009-1870 grant. The authors acknowledge the assistance and advice of Electron Microscopy Service of the UPV. en_EN
dc.language Inglés es_ES
dc.publisher Springer Verlag es_ES
dc.relation.ispartof Journal of Polymer Research es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Self-assembling peptide es_ES
dc.subject Ethyl acrylate es_ES
dc.subject Acrylic acid es_ES
dc.subject Substrate interaction es_ES
dc.subject Wettability es_ES
dc.subject Electron Microscopy Service of the UPV
dc.subject.classification MAQUINAS Y MOTORES TERMICOS es_ES
dc.subject.classification TERMODINAMICA APLICADA (UPV) es_ES
dc.title Interaction between acrylic substrates and RAD16-I peptide in its self-assembling es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1007/s10965-016-1069-3
dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/229239/EU/RECATABI/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MICINN//MAT2011-28791-C03-02/ES/MATERIALES DE SOPORTE Y LIBERACION CONTROLADA PARA LA REGENERACION DE ESTRUCTURAS NEURALES AFECTADAS POR ICTUS/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/ME//FPU2009-1870/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MICINN//MAT2011-28791-C03-03/ES/CONSTRUCTOS PARA LA REGENERACION GUIADA DE ESTRUCTURAS DEL SISTEMA NERVIOSO CENTRAL/ es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Escuela Técnica Superior de Ingenieros Industriales - Escola Tècnica Superior d'Enginyers Industrials es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Termodinámica Aplicada - Departament de Termodinàmica Aplicada es_ES
dc.description.bibliographicCitation Arnal Pastor, MP.; González-Mora, D.; García-Torres, F.; Monleón Pradas, M.; Vallés Lluch, A. (2016). Interaction between acrylic substrates and RAD16-I peptide in its self-assembling. Journal of Polymer Research. 23(9):173-184. https://doi.org/10.1007/s10965-016-1069-3 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://dx.doi. org/10.1007/s10965-016-1069-3 es_ES
dc.description.upvformatpinicio 173 es_ES
dc.description.upvformatpfin 184 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 23 es_ES
dc.description.issue 9 es_ES
dc.relation.senia 325382 es_ES
dc.identifier.eissn 1572-8935
dc.contributor.funder Ministerio de Ciencia e Innovación
dc.contributor.funder Ministerio de Educación
dc.contributor.funder European Commission
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