Coupling two multistep catalytic cycles for the one-pot synthesis of propargylamines from alcohols and primary amines on nanoparticulated gold catalyst

Corma Canós, AvelinoNavas Escrig, JavierSabater Picot, Mª José2013-06-1020120947-6539https://riunet.upv.es/handle/10251/29577[EN] A one-pot reaction was performed with a nanoparticulated gold catalyst. A secondary amine is formed through N-monoalkylation of a primary amine with an alcohol by a borrowing hydrogen methodology in a three-step reaction. The secondary amine formed enters into a second A3-coupling cycle to give propargylamines. The multistep reaction requires a gold species formed and stabilized on a ceria surface.Reserva de todos los derechosAlkylationDomino reactionsGoldHydrogen transferPropargylamineQUIMICA ORGANICACoupling two multistep catalytic cycles for the one-pot synthesis of propargylamines from alcohols and primary amines on nanoparticulated gold catalystArtículo10.1002/chem.201201837Cerrado22996294