Vendrell Criado, VictoriaRodríguez Muñiz, Gemma MaríaCuquerella Alabort, Maria ConsueloLhiaubet, Virginie LyriaMiranda Alonso, Miguel Ángel2015-02-172013-06-171433-78511521-3773https://riunet.upv.es/handle/10251/47184A (photo)sensitive subject: Combined agarose gel electrophoresis and photochemical studies show that 5-methyl-2-pyrimidone (see picture), the main chromophore of (6-4) photoproducts, behaves as a DNA photosensitizer. These results raise the question of whether the (6-4) lesions can act as Trojan horses, enhancing cyclobutane pyrimidine dimer (CPD) formation and oxidative damage.Reserva de todos los derechosCyclobutane pyrimidine dimersDNA damagePhotochemistryPyrimidonesTriplet excited statesQUIMICA ORGANICAQUIMICA ANALITICAArtículo10.1002/anie.201302176Cerrado