Hernandez-Contreras, JordiRoig-Rubio, JordiPARRA ALVAREZ, MARGARITAGIL GRAU, SALVADORArroyo, PauSáez, José A.Lodeiro, CarlosGaviña, Pablo2025-06-122025-06-122024-12https://riunet.upv.es/handle/10251/221734[EN] Chemical submission, a nefarious tactic increasingly employed in criminal activities, has spurred urgent calls for innovative countermeasures. GHB, often dubbed "liquid ecstasy," stands out as a favoured agent for its surreptitious nature and seamless solubility in water and alcoholic beverages. Addressing this menace head-on, a groundbreaking study delves into the development of advanced chemosensors, leveraging 2-aminonaphtoxazoleand benzoxazole-based compounds adorned with fluorescein, to construct a cellulose paper-based detection system. This ingenious setup not only detects GHB in water but extends its vigilance to real alcoholic and nonalcoholic beverages, illuminating a pathway to thwart potential assailants. With a fluorescence enhancement mechanism at play, the system boasts a dynamic range from 0 to 125 mM GHB in water, exhibiting a commendable limit of detection (LOD) at 7.3 mM. Crucially, its eco-friendly nature, devoid of solvent residuals, underscores its suitability as a proactive shield against chemical submission, embodying a beacon of hope in the fight against such insidious threats to public safety.Reconocimiento - No comercial - Sin obra derivada (by-nc-nd)Chemical submissionFluorescent dyesProbesY-Hydroxybutyric acid (GHB)Cellulose paper-based materialSpiked drinksArtículo10.1016/j.sbsr.2024.100691Abierto2214-1804