[EN] Several studies have investigated the differential vulnerability of hippocampal subfields during aging and Alzheimer's disease (AD). Results were often contradictory, mainly because these works were based on concatenations ...
[EN] Background and Purpose:
Many neurological or psychiatric diseases affect the hippocampus during aging. The study of hippocampal regional vulnerability may provide important insights into the pathophysiological ...
[EN] In this article, we present an innovative MRI-based method for Alzheimer disease (AD) detection and mild cognitive impairment (MCI) prognostic, using lifespan trajectories of brain structures. After a full screening ...
Planche, Vincent; Manjón Herrera, José Vicente; Mansecal, Boris; Lanuza, Enrique; Tourdias, Thomas; Catheline, Gwenaelle; Coupé, Pierrick(Oxford University Press, 2022-05-02)
[EN] The chronological progression of brain atrophy over decades, from pre-symptomatic to dementia stages, has never been formally depicted in Alzheimer's disease. This is mainly due to the lack of cohorts with long enough ...